Lymphatic microvessel density is an independent prognostic factor in colorectal cancer

Diseases of the Colon and Rectum

Volumn 50, Issue 3, 2007, Pages 308-314

  Matsumoto, Kentaro ^a   Nakayama, Yoshifumi ^a   Inoue, Yuzuru ^a   Minagawa, Noritaka ^a   Katsuki, Takefumi ^a   Shibao, Kazunori ^a   Tsurudome, Yosuke ^a   Hirata, Keiji ^a   Nagata, Naoki ^a   Itoh, Hideaki ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Colorectal cancer; Lymphangiogenesis; Lymphatic microvessel density; Lymphatic vessel invasion; Podoplanin

Indexed keywords

BIOLOGICAL MARKER; CELL MARKER; PODOPLANIN;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; CANCER INVASION; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DENSITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; LYMPH VESSEL; LYMPH VESSEL ENDOTHELIUM; LYMPHANGIOGENESIS; MALE; MICROVASCULATURE; MULTIVARIATE ANALYSIS; OVERALL SURVIVAL; PATHOLOGY; PROGNOSIS; STATISTICAL ANALYSIS; SURVIVAL RATE; UNIVARIATE ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; LYMPHATIC VESSELS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 33847772421     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/s10350-006-0792-y     Document Type: Article

References (31)

1. CE Dukes HJ Bussey 1958 The spread of rectal cancer and its effect on prognosis Br J Cancer 12 309 320
2. RC Newland PH Chapuis MT Pheils JG [tmp] MacPherson 1981 The relationship of survival to staging and grading of colorectal carcinoma: a prospective study of 503 cases Cancer 47 1424 1429
3. PH Chapuis OF Dent R Fisher 1985 A multivariate analysis of clinical and pathological variables in prognosis after resection of large bowel cancer Br J Surg 72 698 702
4. LP Fielding RK Phillips JS Fry R Hittinger 1986 Prediction of outcome after curative resection for large bowel cancer Lancet 2 904 907
5. P Hermanek 1995 pTNM and residual tumor classifications: problems of assessment and prognostic significance World J Surg 19 184 190
6. S Breitender-Geleff A Soleiman H Kowalski 1999 Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium Am J Pathol 154 385 394
7. JT Wigle G Oliver 1999 Prox1 function is required for the development of the murine lymphatic system Cell 98 769 778
8. S Banerji J Ni SX Wang 1999 LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan J Cell Biol 144 789 801
9. NJ Beasley R Prevo S Banerji 2002 Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer Cancer Res 62 1315 1320
10. SM Maula M Luukkaa R Grenman D Jackson S Jalkanen R Ristamäki 2003 Intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinomas of the head and neck region Cancer Res 63 1920 1926
11. PA Kayzas S Gellef A Batistatou NJ Agnantis D Stefanou 2005 Evidence for lymphangiogenesis and its prognostic implications in head and neck squamous cell carcinoma J Pathol 206 170 177
12. SF Schoppmann G Bayer K Aumayr 2004 Austrian Breast and Colorectal Cancer Study Group. Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer Ann Surg 240 306 312
13. P Bono VM Wasenius P Heikkila J Lundin DG Jackson H Joensuu 2004 High LYVE-1-positive lymphatic vessel numbers are associated with poor outcome in breast cancer Clin Cancer Res 10 7144 7149
14. Y Nakamura H Yasuoka M Tsujimoto 2005 Lymph vessel density correlates with nodal status, VEGF-C expression, and prognosis in breast cancer Breast Cancer Res Treat 91 125 132
15. O Straume DG Jackson LA Akslen 2003 Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma Clin Cancer Res 9 250 256
16. SS Dadras T Paul J Bertoncini 2003 Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival Am J Pathol 162 1951 1960
17. FT Hall JL Freeman SL Asa DG Jackson NJ Beasley 2003 Intratumoral lymphatics and lymph node metastases in papillary thyroid carcinoma Arch Otolaryngol Head Neck Surg 129 716 719
18. H Yasuoka Y Nakamura H Zuo 2005 VEGF-D expression and lymph vessels play an important role for lymph node metastasis in papillary thyroid carcinoma Mod Pathol 18 1127 1133
19. N Weidner J Folkman F Pozza 1992 Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma J Natl Cancer Inst 84 1875 1887
20. N Weidner JP Semple WR Welch J Folkman 1991 Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma N Engl J Med 324 1 8
21. LH Sobin CH Wittekind 2002 International Union Against Cancer. TNM classification of malignant tumors 6 Wiley-Liss New York
22. Japanese Society for Cancer of the Colon and Rectum. 1998 General rules for clinical and pathological studies on cancer of the colon, rectum and anus 6 Kanehara & Co Ltd Tokyo
23. TA Partanen K Alitalo M Miettinen 1999 Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors Cancer 86 2406 2412
24. K Akagi Y Ikeda M Miyazaki 2000 Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues Br J Cancer 83 887 891
25. JD White PW Hewett D Kosuge 2002 Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma Cancer Res 62 1669 1675
26. M Ohno T Nakamura K Kunimoto K Nishimura C Chung-Kang Y Kuroda 2003 Lymphagenesis correlates with expression of vascular endothelial growth factor-C in colorectal cancer Oncol Rep 10 939 943
27. S Onogawa Y Kitadai S Tanaka T Kuwai S Kimura K Chayama 2004 Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma Cancer Sci 95 32 39
28. JS Reis-Filho FC Schmitt 2003 Lymphangiogenesis in tumors: what do we know? Microsc Res Tech 60 171 180
29. RK Jain BT Fenton 2002 Intratumoral lymphatic vessels: a case of mistaken identity or malfunction? J Natl Cancer Inst 94 417 421
30. S Breiteneder-Geleff K Matsui A Soleiman 1997 Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis Am J Pathol 151 1141 1152
31. Y Kitadai M Kodama S Cho 2005 Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes Int J Cancer 115 388 392