Baseline level of platelet-leukocyte aggregates, platelet CD63 expression, and soluble P-selectin concentration in patientswith posttraumatic stress disorder: A pilot study

Psychiatry Research

Volumn 150, Issue 2, 2007, Pages 211-216

  Vidović, Andelko ^a   Vilibić, Maja ^b   Markotić, Alemka ^a   Sabioncello, Ante ^a   Gotovac, Katja ^a   Folnegović Šmalc, Vera ^b   Dekaris, Dragan ^a  

^a INSTITUTE OF IMMUNOLOGY   (Croatia)

^b University of Zagreb   (Croatia)

Author keywords

Cardiovascular disease; Flow cytometry; War veterans

Indexed keywords

CD63 ANTIGEN; PADGEM PROTEIN;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CROATIA; FLOW CYTOMETRY; HUMAN; LEUKOCYTE AGGREGATION; MALE; PILOT STUDY; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; SOLDIER; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

ADULT; ANTIGENS, CD; BLOOD PLATELETS; BODY MASS INDEX; CARDIOVASCULAR DISEASES; COMBAT DISORDERS; CROATIA; FLOW CYTOMETRY; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; P-SELECTIN; PILOT PROJECTS; PLATELET AGGREGATION; PLATELET MEMBRANE GLYCOPROTEINS; RISK FACTORS; VETERANS;

EID: 33847763214     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psychres.2006.05.004     Document Type: Article

References (43)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. (1994), American Psychiatric Press, Washington, DC
2. Blake D.D., Weathers F.W., Nagy L.M., Kaloupek D.G., and Keane T.M. Clinician-Administered PTSD Scale for DSM-IV. Current and Lifetime Diagnostic Version (CAPS-DX) (1996), National Center for Posttraumatic Stress Disorder, Boston and West Haven
3. Blanchard E.B., Kolb L.C., Prins A., Gates S., and McCoy G.C. Changes in plasma norepinephrine to combat-related stimuli among Vietnam veterans with posttraumatic stress disorder. Journal of Nervous and Mental Disease 179 (1991) 371-373
4. Blann A.D., Nadar S.K., and Lip G.Y. The adhesion molecule P-selectin and cardiovascular disease. European Heart Journal 24 (2003) 2166-2179
5. Boscarino J.A., and Chang J. Electrocardiogram abnormalities among men with stress-related psychiatric disorders: implications for coronary heart disease and clinical research. Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine 21 (1999) 227-234
6. Bruce E.C., and Musselman D.L. Depression, alterations in platelet function, and ischemic heart disease. Psychosomatic Medicine 67 Suppl 1 (2005) S34-S36
7. Brydon L., Magid K., and Steptoe A. Platelets, coronary heart disease, and stress. Brain, Behavior, and Immunity 20 (2006) 113-119
8. Buckley T.C., and Kaloupek D.G. A meta-analytic examination of basal cardiovascular activity in posttraumatic stress disorder. Psychosomatic Medicine 63 (2001) 585-594
9. Caine G.J., and Blann A.D. Soluble p-selectin should be measured in citrated plasma, not in serum. British Journal of Haematology 121 (2003) 530-532
10. Camacho A., and Dimsdale J.E. Platelets and psychiatry: lessons learned from old and new studies. Psychosomatic Medicine 62 (2000) 326-336
11. Cicin-Sain L., Mimica N., Hranilovic D., Balija M., Ljubin T., Makaric G., Folnegovic-Smalc V., and Jernej B. Posttraumatic stress disorder and platelet serotonin measures. Journal of Psychiatric Research 34 (2000) 155-161
12. Falger P.R., Op den V.e.W., Hovens J.E., Schouten E.G., De Groen J.H., and Van Duijn H. Current posttraumatic stress disorder and cardiovascular disease risk factors in Dutch Resistance veterans from World War II. Psychotherapy and Psychosomatics 57 (1992) 164-171
13. Furman M.I., Benoit S.E., Barnard M.R., Valeri C.R., Borbone M.L., Becker R.C., Hechtman H.B., and Michelson A.D. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. Journal of the American College of Cardiology 31 (1998) 352-358
14. Gavish M., Laor N., Bidder M., Fisher D., Fonia O., Muller U., Reiss A., Wolmer L., Karp L., and Weizman R. Altered platelet peripheral-type benzodiazepine receptor in posttraumatic stress disorder. Neuropsychopharmacology 14 (1996) 181-186
15. Guy W. Clinical Global Impressions. In: Guy W. (Ed). ECDEU Assessment Manual for Psychopharmacology (1976), National Institute of Mental Health, Rockville, MD 218-222
16. Israels S.J., and McMillan-Ward E.M. CD63 modulates spreading and tyrosine phosphorylation of platelets on immobilized fibrinogen. Thrombosis and Haemostasis 93 (2005) 311-318
17. Israels S.J., McMillan-Ward E.M., Easton J., Robertson C., and McNicol A. CD63 associates with the alphaIIb beta3 integrin-CD9 complex on the surface of activated platelets. Thrombosis and Haemostasis 85 (2001) 134-141
18. Kozaric-Kovacic D., Ljubin T., Rutic-Puz L., Mihaljevic J., Jernej B., and Cicin-Sain L. Platelet monoamine oxidase activity, ego strength, and neuroticism in soldiers with combat-related current posttraumatic stress disorder. Croatian Medical Journal 41 (2000) 76-80
19. Lederbogen F., Baranyai R., Gilles M., Menart-Houtermans B., Tschoepe D., and Deuschle M. Effect of mental and physical stress on platelet activation markers in depressed patients and healthy subjects: a pilot study. Psychiatry Research 127 (2004) 55-64
20. Lerer B., Ebstein R.P., Shestatsky M., Shemesh Z., and Greenberg D. Cyclic AMP signal transduction in posttraumatic stress disorder. American Journal of Psychiatry 144 (1987) 1324-1327
21. Li N., Goodall A.H., and Hjemdahl P. Efficient flow cytometric assay for platelet-leukocyte aggregates in whole blood using fluorescence signal triggering. Cytometry 35 (1999) 154-161
22. Michelson A.D., Barnard M.R., Hechtman H.B., MacGregor H., Connolly R.J., Loscalzo J., and Valeri C.R. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proceedings of the National Academy of Sciences of the United States of America 93 (1996) 11877-11882
23. Michelson A.D., Barnard M.R., Krueger L.A., Frelinger III A.L., and Furman M.I. Evaluation of platelet function by flow cytometry. Methods 21 (2000) 259-270
24. Michelson A.D., Barnard M.R., Krueger L.A., Valeri C.R., and Furman M.I. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation 104 (2001) 1533-1537
25. Nijm J., Wikby A., Tompa A., Olsson A.G., and Jonasson L. Circulating levels of proinflammatory cytokines and neutrophil-platelet aggregates in patients with coronary artery disease. American Journal of Cardiology 95 (2005) 452-456
26. Pasic J., Sullivan M.D., Russo J., Chandler W.L., and Levy W.C. Lack of depression effect on platelet activation in patients with heart failure. Psychiatry Research 129 (2004) 289-292
27. Perry B.D., Giller E.L., and Southwick S.M. Altered platelet alpha 2-adrenergic binding sites in posttraumatic stress disorder. American Journal of Psychiatry 144 (1987) 1511-1512
28. Pivac N., Muck-Seler D., Sagud M., and Jakovljevic M. Platelet serotonergic markers in posttraumatic stress disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 26 (2002) 1193-1198
29. Rinder H.M., Bonan J.L., Rinder C.S., Ault K.A., and Smith B.R. Activated and unactivated platelet adhesion to monocytes and neutrophils. Blood 78 (1991) 1760-1769
30. Rozanski A., Blumenthal J.A., Davidson K.W., Saab P.G., and Kubzansky L. The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology. Journal of the American College of Cardiology 45 (2005) 637-651
31. Semenov A.V., Romanov Y.A., Loktionova S.A., Tikhomirov O.Y., Khachikian M.V., Vasil'ev S.A., and Mazurov A.V. Production of soluble P-selectin by platelets and endothelial cells. Biochemistry (Moscow) 64 (1999) 1326-1335
32. Serebruany V.L., Glassman A.H., Malinin A.I., Sane D.C., Finkel M.S., Krishnan R.R., Atar D., Lekht V., and O'Connor C.M. Enhanced platelet/endothelial activation in depressed patients with acute coronary syndromes: evidence from recent clinical trials. Blood Coagulation and Fibrinolysis: An International Journal in Haemostasis and Thrombosis 14 (2003) 563-567
33. Sibai A.M., Armenian H.K., and Alam S. Wartime determinants of arteriographically confirmed coronary artery disease in Beirut. American Journal of Epidemiology 130 (1989) 623-631
34. Southwick S.M., Paige S., Morgan C.A., Bremner J.D., Krystal J.H., and Charney D.S. Neurotransmitter alterations in PTSD: catecholamines and serotonin. Seminars in Clinical Neuropsychiatry 4 (1999) 242-248
35. Steptoe A., Magid K., Edwards S., Brydon L., Hong Y., and Erusalimsky J. The influence of psychological stress and socioeconomic status on platelet activation in men. Atherosclerosis 168 (2003) 57-63
36. Thom J., Gilmore G., Yi Q., Hankey G.J., and Eikelboom J.W. Measurement of soluble P-selectin and soluble CD40 ligand in serum and plasma. Journal of Thrombosis and Haemostasis: JTH 2 (2004) 2067-2069
37. von Kanel R. Platelet hyperactivity in clinical depression and the beneficial effect of antidepressant drug treatment: how strong is the evidence?. Acta Psychiatrica Scandinavica 110 (2004) 163-177
38. von Kanel R., and Dimsdale J.E. Effects of sympathetic activation by adrenergic infusions on hemostasis in vivo. European Journal of Haematology 65 (2000) 357-369
39. Walsh M.T., Dinan T.G., Condren R.M., Ryan M., and Kenny D. Depression is associated with an increase in the expression of the platelet adhesion receptor glycoprotein Ib. Life Sciences 70 (2002) 3155-3165
40. Walsh M.T., Ryan M., Hillmann A., Condren R., Kenny D., Dinan T., and Thakore J.H. Elevated expression of integrin alpha(IIb) beta(IIIa) in drug-naive, first-episode schizophrenic patients. Biological Psychiatry 52 (2002) 874-879
41. World Health Organization. The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines, Geneva (1992)
42. Yehuda R., Southwick S., Giller E.L., Ma X., and Mason J.W. Urinary catecholamine excretion and severity of PTSD symptoms in Vietnam combat veterans. Journal of Nervous and Mental Disease 180 (1992) 321-325
43. Yehuda R., Siever L.J., Teicher M.H., Levengood R.A., Gerber D.K., Schmeidler J., and Yang R.K. Plasma norepinephrine and 3-methoxy-4-hydroxyphenylglycol concentrations and severity of depression in combat posttraumatic stress disorder and major depressive disorder. Biological Psychiatry 44 (1998) 56-63