Marked increases in bone mineral density and biochemical markers of bone turnover in patients with anorexia nervosa gaining weight

Bone

Volumn 40, Issue 4, 2007, Pages 1073-1077

  Viapiana, Ombretta ^a   Gatti, Davide ^a   Dalle Grave, Riccardo ^b   Todesco, Tiziana ^b   Rossini, Maurizio ^a   Braga, Vania ^a   Idolazzi, Luca ^a   Fracassi, Elena ^a   Adami, Silvano ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b Villa Garda Hospital   (Italy)

Author keywords

Anorexia nervosa; BMD; Bone loss; Bone markers; Weight gain

Indexed keywords

ALKALINE PHOSPHATASE; ALKALINE PHOSPHATASE BONE ISOENZYME; CARBOXY TERMINAL TELOPEPTIDE; OSTEOCALCIN;

ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; AMENORRHEA; ANOREXIA NERVOSA; ARTICLE; BONE DENSITY; BONE TURNOVER; CONTROLLED STUDY; DIET THERAPY; EATING DISORDER; FEMALE; FEMUR NECK; FRAGILITY FRACTURE; HIP; HUMAN; MAJOR CLINICAL STUDY; OSSIFICATION; OSTEOLYSIS; OSTEOPOROSIS; SPINE; WEIGHT GAIN;

ADULT; ALKALINE PHOSPHATASE; ANOREXIA NERVOSA; BIOLOGICAL MARKERS; BONE DENSITY; BONE REMODELING; CASE-CONTROL STUDIES; COLLAGEN TYPE I; FEMALE; HUMANS; OSTEOCALCIN; PEPTIDES; WEIGHT GAIN;

EID: 33847762832     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.11.015     Document Type: Article

References (25)

1. Fairburn C.G., and Harrison P.J. Eating disorders. Lancet 361 (2003) 407-416
2. Sullivan P.F. Mortality in anorexia nervosa. Am. J. Psychiatry 152 (1995) 1073-1074
3. Becker A., Grinspoon S.K., Klibanski A., and Hergoz D.B. Eating disorders. N. Engl. J. Med. 340 (1999) 1092-1098
4. Legroux-Gerot I., Vignau J., Collier F., and Cortet B. Bone loss associated with anorexia nervosa. Joint Bone Spine 72 (2005) 489-495
5. Lucas A.R., Melton III L.J., Crowson C.S., and O'Fallon W.M. Long-term fracture risk among women with anorexia nervosa: a population-based cohort study. Mayo Clin. Proc. 74 (1999) 972-977
6. Rigotti N.A., Neer R.M., Skates S.J., Herzog D.B., and Nussbaum S.R. The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass. JAMA 265 (1991) 1133-1138
7. Grinspoon S., Miller K., Coyle C., Krempin J., Armstrong C., Pitts S., et al. Severity of osteopenia in oestrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea. J. Clin. Endocrinol. Metab. 84 (1999) 2049-2055
8. Bachrach L.K., Katzman D.K., Litt I.F., Guido D., and Marcus R.N. Recovery from osteopenia in adolescent girls with anorexia nervosa. J. Clin. Endocrinol. Metab. (1999) 602-606
9. Stefanis N., Mackintosh C., Abraha H.D., Treasure J., and Moniz C. Dissociation of bone turnover in anorexia nervosa. Ann. Clin. Biochem. 35 (1998) 709-716
10. Valla A., Groenning I.L., Syversen U., and Hoeiseth A. Anorexia nervosa: slow regain of bone mass. Osteoporosis Int. 11 (2000) 141-145
11. Soyka L.A., Misra M., Frenchman A., Miller K.K., Grinspoon S., Schoenfeld D.A., and Klibanski A. Abnormal bone mineral accrual in adolescent girls with anorexia nervosa. J. Clin. Endocrinol. Metab. 87 (2002) 4177-4185
12. Compston J.E., McConachie C., Stott C., Hannon R.A., Kaptoge S., Debiram I., et al. Changes in bone mineral density, body composition and biochemical markers of bone turnover during weight gain in adolescents with severe anorexia nervosa: a 1-year prospective study. Osteoporosis Int. 17 (2006) 77-84
13. Bass S.L., Saxon L., Corral A.M., Rodda C.P., Strauss B.J., Reidpath D., et al. Near normalisation of lumbar spine bone density in young women with osteopenia recovered from adolescent onset anorexia nervosa: a longitudinal study. J. Pediatr. Endocrinol. Metab. 18 (2005) 897-907
14. Bolton J.G.F., Patel S., Lacey J.H., and White S. A prospective study of changes in bone turnover and bone density associated with regaining weight in women with anorexia nervosa. Osteoporosis Int. 16 (2005) 1955-1962
15. Miller K.K., Lee E.E., Lawson E.A., Misra M., Minihan J., Grinspoon S.K., et al. Determinants of skeletal loss and recovery in anorexia nervosa. J. Clin. Endocrinol. Metab. 91 (2006) 2931-2937
16. DSM-IV. Diagnostic and Statistical Manual of Mental Disorders (1994), American Psychiatric Association, Washington, DC
17. Fairburn C.G., Cooper Z., and Shafran R. Cognitive behaviour therapy for eating disorders: a "transdiagnostic" theory and treatment. Behav. Res. Ther. 41 (2003) 509-528
18. Dalle Grave R. A multi-step cognitive behaviour therapy for eating disorders. Eur. Eat. Disord. Rev. 13 (2005) 373-382
19. Grinspoon S., Thomas E., Pitts S., Gross E., Mickley D., Miller K., et al. Prevalence and predictive factors for regional osteoporosis in women with anorexia nervosa. Ann. Intern. Med. 133 (2000) 790-794
20. Soyka L.A., Grinspoon S., Levitsky L.L., Herzog D.B., and Klibanski A. The effects of anorexia nervosa on bone metabolism in female adolescents. J. Clin. Endocrinol. Metab. 84 (1999) 4489-4496
21. Galusca B., Bossu C., Germain N., Kadem M., Frere D., Lafage-Proust M.H., et al. Age-related differences in hormonal and nutritional impact on lean anorexia nervosa bone turnover uncoupling. Osteoporosis Int. 17 (2006) 888-896
22. Grinspoon S., Thomas L., Miller K., Herzog D., and Klibanski A. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J. Clin. Endocrinol. Metab. 87 (2002) 2883-2891
23. Heer M., Mika C., Grzella I., Heussen N., and Herpertz-Dahlmann B. Bone turnover during inpatient nutritional therapy and outpatient follow-up in patients with anorexia nervosa compared with that in healthy control subjects. Am. J. Clin. Nutr. 80 (2004) 774-781
24. Body J.J., Gaich G.A., Scheele W.H., Kulkarni P.M., Miller P.D., Peretz A., et al. A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis. J. Clin. Endocrinol. Metab. 87 (2002) 4528-4535
25. Gordon C.M., Grace E., Emans S.J., Feldman H.A., Goodman E., Becker K.A., et al. Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: a randomised trial. J. Clin. Endocrinol. Metab. 87 (2002) 4935-4941