Effects of parathyroid hormone (1-34) on tibia in an adult rat model for chronic alcohol abuse

Bone

Volumn 40, Issue 4, 2007, Pages 1013-1020

  Sibonga, Jean D ^a   Iwaniec, Urszula T ^b   Shogren, Kristen L ^c   Rosen, Clifford J ^d,e   Turner, Russell T ^b  

^a UNIVERSITIES SPACE RESEARCH ASSOCIATION   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c MAYO CLINIC   (United States)

^d ST JOSEPH HOSPITAL   (United States)

^e JACKSON LABORATORY   (United States)

Author keywords

Bone histomorphometry; Bone remodeling; Bone resorption; Densitometry; Osteoporosis; Serum IGF I

Indexed keywords

ALCOHOL; DEXTRAN; MALTOSE; PARATHYROID HORMONE[1-34];

ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITOMETRY; BONE MASS; BONE TURNOVER; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; DRUG MEGADOSE; MALE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPENIA; OSTEOPOROSIS; RAT; RISK FACTOR; THICKNESS; TIBIA; TREATMENT OUTCOME;

ALCOHOLISM; ANIMALS; BONE DENSITY; BONE DISEASES, METABOLIC; BONE REMODELING; DISEASE MODELS, ANIMAL; HUMANS; MALE; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; TIBIA;

EID: 33847753079     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.11.002     Document Type: Article

References (50)

1. Bikle D.D., Genant H.K., Cann C., Recker R.R., Halloran B.P., and Strewler G.J. Bone disease in alcohol abuse. Ann. Intern. Med. 103 1 (1985) 42-48
2. Diez A., Puig J., Serrano S., Marinoso M.L., Bosch J., Marrugat J., et al. Alcohol-induced bone disease in the absence of severe chronic liver damage. J. Bone Miner. Res. 9 6 (1994) 825-831
3. Pumarino H., Gonzalez P., Oviedo S., Lillo R., and Bustamante E. Assessment of bone status in intermittent and continuous alcoholics, without evidence of liver damage. Rev. Med. Chil. 124 4 (1996) 423-430
4. Turner R.T. Skeletal response to alcohol. Alcohol.: Clin. Exp. Res. 24 11 (2000) 1693-1701
5. Sampson H.W., Chaffin C., Lange J., and DeFee II B. Alcohol consumption by young actively growing rats: a histomorphometric study of cancellous bone. Alcohol.: Clin. Exp. Res. 21 2 (1997) 352-359
6. Sampson H.W., Perks N., Champney T.H., and DeFee II B. Alcohol consumption inhibits bone growth and development in young actively growing rats. Alcohol.: Clin. Exp. Res. 20 8 (1996) 1375-1384
7. Turner R.T., Aloia R.C., Segel L.D., Hannon K.S., and Bell N.H. Chronic alcohol treatment results in disturbed vitamin D metabolism and skeletal abnormalities in rats. Alcohol.: Clin. Exp. Res. 12 1 (1988) 159-162
8. Turner R.T., Greene V.S., and Bell N.H. Demonstration that ethanol inhibits bone matrix synthesis and mineralization in the rat. J. Bone Miner. Res. 2 1 (1987) 61-66
9. Sampson H.W. Effect of alcohol consumption on adult and aged bone: a histomorphometric study of the rat animal model. Alcohol.: Clin. Exp. Res. 22 9 (1998) 2029-2034
10. Turner R.T., Kidder L.S., Kennedy A., Evans G.L., and Sibonga J.D. Moderate alcohol consumption suppresses bone turnover in adult female rats. J. Bone Miner. Res. 16 3 (2001) 589-594
11. Callaci J.J., Juknelis D., Patwardhan A., Sartori M., Frost N., and Wezeman F.H. The effects of binge alcohol exposure on bone resorption and biomechanical and structural properties are offset by concurrent bisphosphonate treatment. Alcohol.: Clin. Exp. Res. 28 1 (2004) 182-191
12. Sampson H.W., and Spears H. Osteopenia due to chronic alcohol consumption by young actively growing rats is not completely reversible. Alcohol.: Clin. Exp. Res. 23 2 (1999) 324-327
13. Body J.J., Gaich G.A., Scheele W.H., Kulkarni P.M., Miller P.D., Peretz A., et al. A randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis. J. Clin. Endocrinol. Metab. 87 10 (2002) 4528-4535
14. Dobnig H., and Turner R.T. The effects of programmed administration of human parathyroid hormone fragment (1-34) on bone histomorphometry and serum chemistry in rats. Endocrinology 138 11 (1997) 4607-4612
15. Lane N.E., Sanchez S., Modin G.W., Genant H.K., Pierini E., and Arnaud C.D. Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial. J. Clin. Invest. 102 8 (1998) 1627-1633
16. Tam C.S., Heersche J.N., Murray T.M., and Parsons J.A. Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration. Endocrinology 110 2 (1982) 506-512
17. Turner R.T., Evans G.L., Zhang M., and Sibonga J.D. Effects of parathyroid hormone on bone formation in a rat model for chronic alcohol abuse. Alcohol.: Clin. Exp. Res. 25 5 (2001) 667-671
18. Lieber C.S., and DeCarli L.M. The feeding of alcohol in liquid diets: two decades of applications and 1982 update. Alcohol.: Clin. Exp. Res. 6 4 (1982) 523-531
19. Martin E.A., Ritman E.L., and Turner R.T. Time course of epiphyseal growth plate fusion in rat tibiae. Bone 32 3 (2003) 261-267
20. Kidder L.S., and Turner R.T. Dietary ethanol does not accelerate bone loss in ovariectomized rats. Alcohol.: Clin. Exp. Res. 22 9 (1998) 2159-2164
21. Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2 6 (1987) 595-610
22. Reed A.H., McCarty H.L., Evans G.L., Turner R.T., and Westerlind K.C. The effects of chronic alcohol consumption and exercise on the skeleton of adult male rats. Alcohol.: Clin. Exp. Res. 26 8 (2002) 1269-1274
23. Peng T.C., Kusy R.P., Hirsch P.F., and Hagaman J.R. Ethanol-induced changes in morphology and strength of femurs of rats. Alcohol.: Clin. Exp. Res. 12 5 (1988) 655-659
24. Wezeman F.H., Emanuele M.A., Emanuele N.V., Moskal II S.F., Woods M., Suri M., et al. Chronic alcohol consumption during male rat adolescence impairs skeletal development through effects on osteoblast gene expression, bone mineral density, and bone strength. Alcohol.: Clin. Exp. Res. 23 9 (1999) 1534-1542
25. Hogan H.A., Sampson H.W., Cashier E., and Ledoux N. Alcohol consumption by young actively growing rats: a study of cortical bone histomorphometry and mechanical properties. Alcohol.: Clin. Exp. Res. 21 5 (1997) 809-816
26. Turner R.T., Spector M., and Bell N.H. Ethanol induced abnormalities in bone formation, turnover, mechanical properties, and mineralization in young adult rats. Cell Mater. Suppl. 1 1 (1991) 167-173
27. Hogan H.A., Argueta F., Moe L., Nguyen L.P., and Sampson H.W. Adult-onset alcohol consumption induces osteopenia in female rats. Alcohol.: Clin. Exp. Res. 25 5 (2001) 746-754
28. Wakley G.K., Schutte Jr. H.D., Hannon K.S., and Turner R.T. Androgen treatment prevents loss of cancellous bone in the orchidectomized rat. J. Bone Miner. Res. 6 4 (1991) 325-330
29. Turner R.T., Hannon K.S., Demers L.M., Buchanan J., and Bell N.H. Differential effects of gonadal function on bone histomorphometry in male and female rats. J. Bone Miner. Res. 4 4 (1989) 557-563
30. Bikle D.D., Stesin A., Halloran B., Steinbach L., and Recker R. Alcohol-induced bone disease: relationship to age and parathyroid hormone levels. Alcohol.: Clin. Exp. Res. 17 3 (1993) 690-695
31. Gonzalez-Calvin J.L., Garcia-Sanchez A., Bellot V., Munoz-Torres M., Raya-Alvarez E., and Salvatierra-Rios D. Mineral metabolism, osteoblastic function and bone mass in chronic alcoholism. Alcohol Alcohol. 28 5 (1993) 571-579
32. Laitinen K., Tahtela R., Luomanmaki K., and Valimaki M.J. Mechanisms of hypocalcemia and markers of bone turnover in alcohol-intoxicated drinkers. Bone Miner. 24 3 (1994) 171-179
33. Crilly R.G., Anderson C., Hogan D., and Delaquerriere-Richardson L. Bone histomorphometry, bone mass, and related parameters in alcoholic males. Calcif. Tissue Int. 43 5 (1988) 269-276
34. Lalor B.C., France M.W., Powell D., Adams P.H., and Counihan T.B. Bone and mineral metabolism and chronic alcohol abuse. Q. J. Med. 59 229 (1986) 497-511
35. Schnitzler C.M., and Solomon L. Bone changes after alcohol abuse. S. Afr. Med. J. 66 19 (1984) 730-734
36. Harding A., Dunlap J., Cook S., Mattalino A., Azar F., O'Brien M., et al. Osteoporotic correlates of alcoholism in young males. Orthopedics 11 2 (1988) 279-282
37. Odvina C.V., Safi I., Wojtowicz C.H., Barengolts E.I., Lathon P., Skapars A., et al. Effect of heavy alcohol intake in the absence of liver disease on bone mass in black and white men. J. Clin. Endocrinol. Metab. 80 8 (1995) 2499-2503
38. Klein R.F., and Carlos A.S. Inhibition of osteoblastic cell proliferation and ornithine decarboxylase activity by ethanol. Endocrinology 136 8 (1995) 3406-3411
39. Klein R.F., Fausti K.A., and Carlos A.S. Ethanol inhibits human osteoblastic cell proliferation. Alcohol.: Clin. Exp. Res. 20 3 (1996) 572-578
40. Maran A., Zhang M., Spelsberg T.C., and Turner R.T. The dose-response effects of ethanol on the human fetal osteoblastic cell line. J. Bone Miner. Res. 16 2 (2001) 270-276
41. Hodsman A.B., Bauer D.C., Dempster D.W., Dian L., Hanley D.A., Harris S.T., et al. Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use. Endocr. Rev. 26 5 (2005) 688-703
42. Dobnig H., and Turner R.T. Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 136 8 (1995) 3632-3638
43. Ejersted C., Andreassen T.T., Nilssen M.H.L., and Oxlund H. Human parathyroid hormone (1-34) increases bone formation and strength of cortical bone in aged rats. Eur. J. Endocrinol. 130 (1994) 201-207
44. Turner R.T., Lotinun S., Hefferan T.E., and Morey-Holton E. Disuse in adult male rats attenuates the bone anabolic response to a therapeutic dose of parathyroid hormone. J. Appl. Physiol. 101 3 (2006) 881-886
45. Robling A.G., Castillo A.B., and Turner C.H. Biomechanical and molecular regulation of bone remodeling. Annu. Rev. Biomed. Eng. 8 (2006) 455-498
46. Bikle D.D., Sakata T., Leary C., Elalieh H., Ginzinger D., Rosen C.J., et al. Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone. J. Bone Miner. Res. 17 9 (2002) 1570-1578
47. Onyia J.E., Helvering L.M., Gelbert L., Wei T., Huang S., Chen P., et al. Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: an analysis by DNA microarray. J. Cell. Biochem. 95 2 (2005) 403-418
48. Watson P., Lazowski D., Han V., Fraher L., Steer B., and Hodsman A. Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats. Bone 16 3 (1995) 357-365
49. Schmidt I.U., Dobnig H., and Turner R.T. Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats. Endocrinology 136 11 (1995) 5127-5134
50. Turner R.T., Wronski T.J., Zhang M., Kidder L.S., Bloomfield S.A., and Sibonga J.D. Effects of ethanol on gene expression in rat bone: transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors, and cytokines are followed by reductions in bone formation. Alcohol.: Clin. Exp. Res. 22 7 (1998) 1591-1599