Clematis vitalba L. aerial part exhibits potent anti-inflammatory, antinociceptive and antipyretic effects

Journal of Ethnopharmacology

Volumn 110, Issue 3, 2007, Pages 504-515

  Yesilada, Erdem ^a   Küpeli, Esra ^b  

^a YEDITEPE UNIVERSITY   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

Author keywords

4 O coumaroyl isovitexine; Anti inflammatory; Antinociceptive; Antipyretic; C glycosylflavone; Clematis vitalba L.; Ranunculaceae; vitalboside

Indexed keywords

1,4 BENZOQUINONE; ACETIC ACID; ACETYLSALICYLIC ACID; CARRAGEENAN; CASTOR OIL; CLEMATIS VITALBA EXTRACT; FREUND ADJUVANT; INDOMETACIN; PLANT EXTRACT; PROSTAGLANDIN E2; SEROTONIN; UNCLASSIFIED DRUG; VITALBOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ANTIPYRETIC ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; BODY TEMPERATURE; CLEMATIS; CLEMATIS VITALBA; DIARRHEA; DOSE RESPONSE; FRACTIONATION; INFLAMMATION; MALE; MOUSE; NONHUMAN; PAW EDEMA; RAT; RHEUMATIC DISEASE; TRADITIONAL MEDICINE; WRITHING TEST;

ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS; BODY TEMPERATURE; CAPILLARY PERMEABILITY; CLEMATIS; COUMARINS; DIARRHEA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; INFLAMMATION; ISOFLAVONES; MALE; MEDICINE, TRADITIONAL; MICE; PAIN; PAIN MEASUREMENT; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

CLEMATIS; CLEMATIS VITALBA; MUS; RANUNCULACEAE;

EID: 33847744582     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.10.016     Document Type: Article

References (29)

1. Awouters F., Niemegeers C.J.E., Lenaerts F.M., and Janssen P.A.J. Delay of castor oil diarrhoea in rats: a new way to evaluate inhibitors of prostaglandin biosynthesis. Journal of Pharmacy and Pharmacology 30 (1978) 41-45
2. Bilingham M.E.J., and Davies E. Experimental models of arthritis in animals as screening tests for drugs to treat arthritis in man. Handbook of Experimental Pharmacology 50 (1979) 108-144
3. Cheng G., Bai Y., Zhao Y., Tao J., Liu Y., Tu G., Ma L., Liao N., and Xu X. Flavonoids from Ziziphus jujuba Mill. var. spinosa. Tetrahedron 56 (2000) 8915-8920
4. Choi J.H., Kim D.Y., Yoon J.H., Youn H.Y., Yit J.B., Rheet H.I., Ryut K.H., Jung K., Hant C.K., and Chot Y.B. Effect of SKI 306X, a new herbal agent, on proteoglycan degradation in cartilage explant culture and collagenase-induced rabbit osteoarthritis model. Osteroarthritis and Cartilage 10 (2002) 471-478
5. Crublet M.L., Long C., Sevenet T., Hadi H.A., and Lavaud C. Acylated flavonol glycosides from leaves of Planchonia grandis. Phytochemistry 64 (2003) 589-594
6. Didry N., Dubreuil L., and Pinkas M. Microbiological properties of protoanemonin isolated from Ranunculus bulbosus. Phytotherapy Research 7 (1993) 21-24
7. Grieve M. In: Leyel C.F. (Ed). A Modern Herbal (1994), Tiger Books International, London 207-208
8. Haribal M., and Renwick J.A. Isovitexin 6″-O-β-d-glucopyranoside: a feeding deterrent to Pieris napi Olearacea from Alliaria petiolata. Phytochemistry 47 (1998) 1237-1240
9. Jung Y.B., Roh K.J., Jung J.A., Jung K., Yoo H., Cho Y.B., Kwak W.J., Kim D.K., Kim K.H., and Han C.K. Effect on SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study. American Journal of Chinese Medicine 29 (2001) 458-491
10. Kasahara Y., Hikino H., Tsurufiji S., Watanabe M., and Ohuchi K. Antiinflammatory actions of ephedrines in acute inflammations. Planta Medica 51 (1985) 325-331
11. Keys, D.J., 1985. Chinese Herbs, The Botany, Chemistry and Pharmacodynamics. Third Press, Charles E. Tutle Company, Tokyo, Japan, pp. 159-160.
12. Latte K.P., Ferreira D., Venkatraman M.S., and Kolodjiez H. O-Galloyl-C-glycosylflavones from Pelargonium reniforme. Phytochemistry 59 (2002) 419-424
13. Li R.W., Lin G.D., Myers S.P., and Leach D.N. Anti-inflammatory activity of Chinese medicinal vine plants. Journal of Ethnopharmacology 85 (2003) 61-67
14. Li R.W., Myers S.P., Leach D.N., Lin G.D., and Leach G. A cross-cultural study: anti-inflammatory activity of Australian and Chinese plants. Journal of Ethnopharmacology 85 (2002) 1-8
15. Maatoq G.T., El-Sharkawy S.H., Afifi M.S., and Rosazza J.P.N. C-p-hydroxybenzoylglycoflavones from Citrillus colocynthis. Phytochemistry 44 (1997) 187-190
16. Newbould B.B. Chemotherapy of polyarthritis induced in rats by mycobacterial adjuvant. British Journal of Pharmacology 21 (1963) 127-136
17. Okun R., Liddon S.C., and Lasagnal L. The effect of aggregation, electric shock and adrenergic bloking drugs on inhibition of the "writhing syndrome". Journal of Pharmacology and Experimental Therapeutics 139 (1963) 107-109
18. Gruenwald J., Brendler T., and Jaenicke C. PDR for Herbal Medicines. second ed. (2000), Montvale, New Jersey p. 769
19. Pieroni A., Nebel S., Quave C., Munz H., and Heinrich M. Ethnopharmacology of Liakra: traditional weedy vegetables of the Arbëreshë of the vulture area in southern Italy. Journal of Ethnopharmacology 81 (2002) 165-185
20. Shanahan R.W. Local activity of anti-inflammatory and irritant agents on rat paw oedema induced by carrageenin. Pharmacologist 10 (1968) 184
21. Southwell I.A., and Tucker D.J. Protoanemonin in Australian Clematis. Phytochemistry 33 (1993) 1099-1102
22. Vallini G., Frassinetti S., D'andrea F., Catelani G., and Agnolucci M. Biodegradation of 4-(1-nonyl) phenol by axenic cultures of the yeast Candida aquaetextoris: identification of microbial breakdown products and proposal of a possible metabolic pathway. International Biodeterioration & Biodegradation 47 (2001) 133-140
23. Wei M.J., Luo X., Wang X., and Zhu J.S. Study of chemical pattern recognition as applied to quality assessment of the traditional Chinese medicine "wei ling xian". Yao Xue Xue Bao 26 (1991) 772-776
24. Yesilada E., and Küpeli E. Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. Journal of Ethnopharmacology 79 (2002) 237-248
25. Yesilada E., Tanaka S., Sezik E., and Tabata M. Isolation of anti-inflammatory principle from the fruit juice of Ecbalium elaterium. Journal of Natural Products 51 (1988) 504-508
26. Yesilada E., Honda G., Sezik E., Tabata M., Fujita T., Tanaka T., Takeda Y., and Takaishi Y. Traditional medicine in Turkey. V. Folk medicine in the inner Taurus mountains. Journal of Ethnopharmacology 46 (1995) 133-152
27. Yesilada E., Ustun O., Sezik E., Takaishi Y., Ono Y., and Honda G. Inhibitory effect of Turkish folk remedies on inflammatory cytokines: interleukin-1α, interleukin-1β and tumor necrosis factor α. Journal of Ethnopharmacology 58 (1997) 59-73
28. Yesilada, E., 1991. Bitkilerde Antienflamatuvar Aktivite Tayininde Kullani{dotless}lan Yöntemler (Methods employed for the anti-inflammatory activity assessment in plants). In: Başer, K.H.C. (Ed.), IXth Bitkisel İlaç Hammaddeleri Toplanti{dotless}si{dotless} Bildiri Kitabi{dotless}. Eskisehir, Turkey, pp. 94-109.
29. Yesilada E., Sezik E., Honda G., Takaishi Y., Takeda Y., and Tanaka T. Traditional medicine in Turkey. IX. Folk medicine in north-west Anatolia. Journal of Ethnopharmacology 64 (1999) 195-210