A Role for HO-1 in Renal Function Impairment in Animals Subjected to Ischemic and Reperfusion Injury and Treated With Immunosuppressive Drugs

Transplantation Proceedings

Volumn 39, Issue 2, 2007, Pages 424-426

  Feitoza, C Q ^a   Goncalves G M ^a   Bertocchi, A P F ^a   Wang, P W ^a   Damiao M J ^a   Cenedeze, M A ^a   Teixeira, V P A ^b   dos Reis, M A ^b   Pacheco Silva, A ^a   Camara N O S ^c  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOSPORIN; HEME OXYGENASE 1; IMMUNOSUPPRESSIVE AGENT; RAPAMYCIN; TACROLIMUS; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CHRONIC GRAFT DYSFUNCTION; CONTROLLED STUDY; DISEASE EXACERBATION; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GRAFT DYSFUNCTION; KIDNEY DYSFUNCTION; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; MALE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; UPREGULATION;

ANIMALS; CYCLOSPORINE; HEME OXYGENASE-1; IMMUNOSUPPRESSIVE AGENTS; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; MALE; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SIROLIMUS; TACROLIMUS; TRANSCRIPTION, GENETIC;

EID: 33847724717     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.01.035     Document Type: Article

References (16)

1. Ojo A.O., Wolfe R.A., Held P.J., et al. Delayed graft function: risk factors and implications for renal allograft survival. Transplantation 63 (1997) 968
2. Tilney N.L., and Guttmann R.D. Effects of initial ischemia/reperfusion injury on the transplanted kidney. Transplantation 64 (1997) 945
3. Azuma H., Nadeau K., Takada M., et al. Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/reperfusion injury of a single kidney. Transplantation 64 (1997) 190
4. Libby P., and Pober J.S. Chronic rejection. Immunity 14 (2001) 387
5. Shoskes D.A., and Halloran P.F. Delayed graft function in renal transplantation: etiology, management and long-term significance. J Urol 155 (1996) 1831
6. Kieran N.E., and Rabb H. Immune responses in kidney preservation and reperfusion injury. J Investig Med 52 (2004) 310
7. Versteilen A.M., Di Maggio F., Leemreis J.R., et al. Molecular mechanisms of acute renal failure following ischemia/reperfusion. Int J Artif Organs 27 (2004) 1019
8. Perico N., Cattaneo D., Sayegh M.H., et al. Delayed graft function in kidney transplantation. Lancet 364 (2004) 1814
9. Meier-Kriesche H.U., Schold J.D., and Kaplan B. Long-term renal allograft survival: have we made significant progress or is it time to rethink our analytic and therapeutic strategies?. Am J Transplant 4 (2004) 1289
10. Cattaneo D., Perico N., and Remuzzi G. Nephrotoxic aspects of cyclosporine. Transplant Proc 36 2 Suppl (2004) 234S
11. Fellström B. Cyclosporine nephrotoxicity. Transplant Proc 36 2 Suppl (2004) 220S
12. Bach F.H., Hancock W.W., and Ferran C. Protective genes expressed in endothelial cells - a regulatory response to injury. Immunol Today 18 (1997) 48
13. Camara N.O.S., and Soares M.P. Heme oxygenase-1 (HO-1), a protective gene that prevents chronic graft dysfunction. Free Rad Biol Med 38 (2005) 426
14. Soares M.P., Brouard S., Smith R.N., et al. Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs. Immunol Rev 184 (2001) 275
15. Goncalves G.M., Cenedeze M.A., Feitoza C.Q., et al. The role of heme oxygenase 1 in rapamycin-induced renal disfunction after ischemia and reperfusion injury. Kidney Int 70 (2006) 1742
16. Lieberthal W., Fuhro R., Andry C.C., et al. Rapamycin impairs recovery from acute renal faiure: role of cell-cycle arrest and apoptosis of tubular cells. Am J Physiol Renal Physiol 281 (2001) F693