Risk factors for hospitalization for bacterial or viral infection in renal transplant recipients - An analysis of USRDS data

American Journal of Transplantation

Volumn 7, Issue 3, 2007, Pages 653-661

  Dharnidharka, V R ^a   Agodoa, L Y ^b   Abbott, K C ^c,d  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c WALTER REED ARMY MEDICAL CENTER   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Bacterial; Infection; Kidney transplantation; Pediatrics; Viral infection

Indexed keywords

ACUTE GRAFT REJECTION; ADULT; ARTICLE; BACTERIAL INFECTION; CELLULITIS; CHRONIC PYELONEPHRITIS; CONFIDENCE INTERVAL; CYTOMEGALOVIRUS; DATA ANALYSIS; DELAYED GRAFT FUNCTION; DIABETES MELLITUS; FEMALE; GRAFT RECIPIENT; HAZARD RATIO; HOSPITALIZATION; HUMAN; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; LEG DISEASE; LOBAR PNEUMONIA; MAJOR CLINICAL STUDY; MALE; MEDICARE; PHARYNGITIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RISK FACTOR; SEPSIS; SEPTICEMIA; TIME SERIES ANALYSIS; UNITED STATES; VIRUS INFECTION;

EID: 33847722694     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01674.x     Document Type: Article

References (35)

1. Dharnidharka VR, Caillard S, Agodoa LY, Abbott KC. Infection frequency and profile in different age groups of kidney transplant recipients. Transplantation 2006 Jun 27; 81: 1662-1667.
2. Dharnidharka VR, Stablein DM, Harmon WE. Post-transplant infections now exceed acute rejection as cause for hospitalization: A report of the NAPRTCS. Am J Transplant 2004; 4: 384-389.
3. Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, Stablein D. Improved graft survival after renal transplantation in the United States, 1988 to 1996. N Engl J Med 2000; 342: 605-612.
4. Meier-Kriesche HU, Schold JD, Srinivas TR, Kaplan B. Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. Am J Transplant 2004; 4: 378-383.
5. Borchers AT, Perez R, Kaysen G, Ansari AA, Gershwin ME. Role of cytomegalovirus infection in allograft rejection: A review of possible mechanisms. Transpl Immunol 1999; 7: 75-82.
6. Foley RN, Guo H, Snyder JJ, Gilbertson DT, Collins AJ. Septicemia in the United States dialysis population, 1991 to 1999. J Am Soc Nephrol 2004; 15: 1038-1045.
7. Ramos E, Drachenberg CB, Papadimitriou JC et al. Clinical course of polyoma virus nephropathy in 67 renal transplant patients. J Am Soc Nephrol 2002; 13: 2145-2151.
8. Meier-Kriesche HU, Ojo AO, Hanson JA, Kaplan B. Exponentially increased risk of infectious death in older renal transplant recipients. Kidney Int 2001; 59: 1539-1543.
9. Abbott KC, Oglesby RJ, Agodoa LY. Hospitalized avascular necrosis after renal transplantation in the United States. Kidney Int 2002; 62: 2250-2256.
10. Abbott KC, Oglesby RJ, Hypolite IO et al. Hospitalizations for fractures after renal transplantation in the United States. Ann Epidemiol 2001; 11: 450-457.
11. Szklo M, Nieto FJ. Stratification and adjustment: Multivariate analysis in epidemiology. In: Epidemiology: Beyond the Basics. Gaithersburg: Aspen Publishers, 2000: 257.
12. Schafer JL. Multiple imputation: A primer. Stat Methods Med Res 1999; 8: 3-15.
13. Ball AM, Gillen DL, Sherrard D et al. Risk of hip fracture among dialysis and renal transplant recipients. JAMA 2002; 288: 3014-3018.
14. Ojo AO, Meier-Kriesche HU, Hanson JA et al. The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation 2001; 71: 82-90.
15. Peeters P, Terryn W, Vanholder R, Lameire N. Delayed graft function in renal transplantation. Curr Opin Crit Care 2004; 10: 489-498.
16. Quiroga I, McShane P, Koo DD et al. Major effects of delayed graft function and cold ischaemia time on renal allograft survival. Nephrol Dial Transplant 2006.
17. Abbott KC, Oliver JD, 3rd, Hypolite I et al. Hospitalizations for bacterial septicemia after renal transplantation in the United States. Am J Nephrol 2001; 21: 120-127.
18. Abbott KC, Swanson SJ, Richter ER et al. Late urinary tract infection after renal transplantation in the United States. Am J Kidney Dis 2004; 44: 353-362.
19. Abbott KC, Hypolite IO, Viola R et al. Hospitalizations for cytomegalovirus disease after renal transplantation in the United States. Ann Epidemiol 2002; 12: 402-409.
20. Song AT, Abdala E, Bonazzi PR, Bacchella T, Machado MC. Does mycophenolate mofetil increase the risk of cytomegalovirus infection in solid organ transplant recipients? - A mini-review. Braz J Infect Dis 2006; 10: 132-138.
21. Randhawa P, Brennan DC. BK virus infection in transplant recipients: An overview and update. Am J Transplant 2006.
22. Hariharan S, Kasiske B, Matas A, Cohen A, Harmon W, Rabb H. Surrogate markers for long-term renal allograft survival. Am J Transplant 2004; 4: 1179-1183.
23. Kahan BD. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study. The Rapamune US Study Group. Lancet 2000; 356: 194-202.
24. Sollinger HW. Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation 1995; 60: 225-232.
25. de Otero J, Gavalda J, Murio E et al. Cytomegalovirus disease as a risk factor for graft loss and death after orthotopic liver transplantation. Clin Infect Dis 1998; 26: 865-870.
26. Reinke P, Fietze E, Ode-Hakim S et al. Late-acute renal allograft rejection and symptomless cytomegalovirus infection. Lancet 1994; 344: 1737-1738.
27. Kutinova A, Woodward RS, Ricci JF, Brennan DC. The incidence and costs of sepsis and pneumonia before and after renal transplantation in the United States. Am J Transplant 2005: doi:10.1111(j.600-6143.2005.01156.x
28. Brayman KL, Stephanian E, Matas AJ et al. Analysis of infectious complications occurring after solid-organ transplantation. Arch Surg 1992; 127: 38-47; discussion 8.
29. Chavers BM, Gillingham KJ, Matas AJ. Complications by age in primary pediatric renal transplant recipients. Pediatr Nephrol 1997; 11: 399-403.
30. Ko KS, Cho DO, Ahn JH et al. Infections after renal transplantation. Transplant Proc 1994; 26: 2072-2074.
31. Maraha B, Bonten H, van Hooff H, Fiolet H, Buiting AG, Stobberingh EE. Infectious complications and antibiotic use in renal transplant recipients during a 1-year follow-up. Clin Microbiol Infect 2001; 7: 619-625.
32. Martinez-Marcos F, Cisneros J, Gentil M et al. Prospective study of renal transplant infections in 50 consecutive patients. Eur J Clin Microbiol Infect Dis 1994; 13: 1023-1028.
33. Their M, Holmberg C, Lautenschlager I, Hockerstedt K, Jalanko H. Infections in pediatric kidney and liver transplant patients after perioperative hospitalization. Transplantation 2000; 69: 1617-1623.
34. Kusne S, Dummer JS, Singh N et al. Infections after liver transplantation. An analysis of 101 consecutive cases. Medicine (Baltimore) 1988; 67: 132-143.
35. Brennan DC, Agha I, Bohl DL et al. Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction. Am J Transplant 2005; 5: 582-594.