Synthesis and antibacterial activity of 3-(4-piperazin-1-yl-phenyl)-s- triazolo [3,4-b] [1,3,4] thiadiazole hydrochlorides

Yaoxue Xuebao

Volumn 42, Issue 1, 2007, Pages 54-57

  Hu, Guo Qiang ^a   Sun, Mao Feng ^a   Xie, Song Qiang ^a   Huang, Wen Long ^b   Zhang, Hui Bin ^b  

^a HENAN UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Antibacterial activity; Phase transfer catalyst; s triazolo 3,4 b 1,3,4 thiadiazole

Indexed keywords

ANTIINFECTIVE AGENT; THIADIAZOLE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; BACILLUS SUBTILIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ESCHERICHIA COLI; MICROBIOLOGICAL EXAMINATION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES; TRIAZOLES;

EID: 33847712942     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Hui XP, Zhang YX, Xu PF, et al. Synthesis and antibacterial activities of novel 4-substituted-6-(4-chlorophenyl)-7-(1H-1, 2, 4-triazol-1-yl) -1', 2', 4'-triazolo [3,4-b]-l",3",4"-thiadiazines [J]. Chin J Org Chem, 2005,25:700-704.
2. Hu GQ, Xie SQ, Xu QJ, et al. Synthesis and antibacterial activity of 3-(5-substituted phenyl-[1,3,4] oxadiazole-2-yl-methylenethio)-5-pyridin-3-yl- [1,2,4] triazole-4-yl-amines [J]. Acta Pharm Sin, 2005,40:337-339.
3. Shi HJ, Wang ZY, Shi HX. Synthesis and antibacterial activities of 3, 6-disubstituted-5, 6-dihydrogen- 1,2,4-s-triazolo[3,4-b]-1,3,4-thiazoles [J]. Acta Pharm Sin, 2001,36:310-312.
4. Liu FM, Ablajan K, Wang HY, et al. Synthesis of s-triazolo[3,4-b]-1,3,4- thiadiazie, imidazolo [2,1-b]-1, 3,4-thiadiazole and imidazolo [2,1-b] -1,3,4-oxadiazole derivatives containing isoxazole [J]. Chem J Chin Univ, 2004, 25:1673-1675.
5. Ye FQ, Ding YM, Chen L, et al. Synthesis and antibacterial activity of ciprofloxacin derivatives [J]. Acta Pharm Sin, 2005, 40:132-135.
6. Heeres J, Backx LJJ, Mostmans JH, et al. Antimycoticazoles. 7. Synthesis and antifungal properties of a series of novel triazol-3-ones [J]. J Med Chem, 1984, 27:894-900.
7. Lounis N, Roscigno G. In vitro and in vivo activities of new rifamycin derivatives against mycobacterial infections [J]. Curr Pharm Des, 2004, 10:3229-3238.
8. Hu GQ, Zhang ZQ, Xu QT, et al. Phase transfer catalyzed synthesis and bioactivity of s-triazolo [3, 42b] thiadiazoles [J]. Acta Chim Sin, 2004, 62:204-207.
9. Qiao RZ, Hui XP, Xu PF, et al. Microwave induced synthesis of 3-aryl-6-(6-/8-substituted 4-chloroquinoline-3-yl)-s-triazolo[3,4-b]-1,3,4- thiadiazoles [J]. Chin J Chem, 2001,19:800-806.