Histological and immunohistochemical analysis of initial and early subepithelial connective tissue attachment at chemically modified and conventional SLA® titanium implants. A pilot study in dogs

Clinical Oral Investigations

Volumn 11, Issue 3, 2007, Pages 245-255

  Schwarz, Frank ^a   Herten, Monika ^a   Sager, Martin ^a   Wieland, Mrco ^b   Dard, Michel ^b   Becker, Jürgen ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b INSTITUT STRAUMANN AG   (Switzerland)

Author keywords

Animal study; Histology; Immunohistochemistry; Sandblasted and acid etched surface; Soft tissue integration; Titanium surface

Indexed keywords

AZO COMPOUND; BIOMEDICAL AND DENTAL MATERIALS; COLLAGEN; COLORING AGENT; CYCLINE; DIAGNOSTIC AGENT; EOSIN; FIBRONECTIN; METHYL GREEN; MONOCLONAL ANTIBODY; TITANIUM;

ANIMAL; ARTICLE; CHEMISTRY; COMPARATIVE STUDY; CONNECTIVE TISSUE; DENTAL ACID ETCHING; DOG; EPITHELIUM; FEMALE; IMMUNOHISTOCHEMISTRY; METHODOLOGY; PATHOLOGY; PERIODONTAL LIGAMENT; PILOT STUDY; SURFACE PROPERTY; TIME; TOOTH IMPLANTATION; TOOTH PROSTHESIS; TRICHROME STAIN; ULTRASTRUCTURE; VASCULARIZATION;

ACID ETCHING, DENTAL; ANIMALS; ANTIBODIES, MONOCLONAL; AZO COMPOUNDS; COLLAGEN; COLORING AGENTS; CONNECTIVE TISSUE; DENTAL IMPLANTS; DENTAL MATERIALS; DENTAL PROSTHESIS DESIGN; DOGS; EOSINE YELLOWISH-(YS); EPITHELIUM; FEMALE; FIBRONECTINS; IMMUNOHISTOCHEMISTRY; METHYL GREEN; PERIODONTAL LIGAMENT; PILOT PROJECTS; PROLIFERATING CELL NUCLEAR ANTIGEN; SURFACE PROPERTIES; TIME FACTORS; TITANIUM;

EID: 33847708445     PISSN: 14326981     EISSN: 14363771     Source Type: Journal    
DOI: 10.1007/s00784-007-0110-7     Document Type: Article

References (45)

1. Abrahamsson I, Berglundh T, Glantz PO, Lindhe J (1998) The mucosal attachment at different abutments. An experimental study in dogs. J Clin Periodontol 25:721-727
2. Abrahamsson I, Berglundh T, Moon IS, Lindhe J (1999) Peri-implant tissues at submerged and non-submerged titanium implants. J Clin Periodontol 26:600-607
3. Abrahamsson I, Berglundh T, Wennstrom J, Lindhe J (1996) The peri-implant hard and soft tissues at different implant systems. A comparative study in the dog. Clin Oral Implants Res 7:212-219
4. Albrektsson T (1983) Direct bone anchorage of dental implants. J Prosthet Dent 50:255-261
5. Albrektsson T, Isidor F (1994) Consensus report of session IV. In: Lang, NP, Karring, T (eds) Proceedings of the first European workshop on periodontology. Quintessence, London, pp 365-369
6. Becker J, Kirsch A, Schwarz F, Chatzinikolaidou M, Rothamel D, Lekovic V, Laub M, Jennissen HP (2006) Bone apposition to titanium implants biocoated with recombinant human bone morphogenetic protein-2 (rhBMP-2). A pilot study in dogs. Clin Oral Investig 10:217-224
7. Berglundh T, Lindhe J (1996) Dimension of the periimplant mucosa. Biological width revisited. J Clin Periodontol 23:971-973
8. Berglundh T, Lindhe J, Ericsson I, Marinello CP, Liljenberg B, Thomsen P (1991) The soft tissue barrier at implants and teeth. Clin Oral Implants Res 2:81-90
9. Berglundh T, Lindhe J, Jonsson K, Ericsson I (1994) The topography of the vascular systems in the periodontal and peri-implant tissues in the dog. J Clin Periodontol 21:189-193
10. Bollen CM, Lambrechts P, Quirynen M (1997) Comparison of surface roughness of oral hard materials to the threshold surface roughness for bacterial plaque retention: A review of the literature. Dent Mater 13:258-269
11. Brånemark PI, Hansson BO, Adell R, Breine U, Lindstrom J, Hallen O, Ohman A (1977) Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scand J Plast Reconstr Surg Suppl 16:1-132
12. Buser D, Broggini N, Wieland M, Schenk RK, Denzer AJ, Cochran DL, Hoffmann B, Lussi A, Steinemann SG (2004) Enhanced bone apposition to a chemically modified SLA titanium surface. J Dent Res 83:529-533
13. Buser D, Weber HP, Donath K, Fiorellini JP, Paquette DW, Williams RC (1992) Soft tissue reactions to non-submerged unloaded titanium implants in beagle dogs. J Periodontol 63:225-235
14. Chehroudi B, Gould TR, Brunette DM (1992) The role of connective tissue in inhibiting epithelial downgrowth on titanium-coated percutaneous implants. J Biomed Mater Res 26:493-515
15. Cochran DL, Hermann JS, Schenk RK, Higginbottom FL, Buser D (1997) Biologic width around titanium implants. A histometric analysis of the implanto-gingival junction around unloaded and loaded nonsubmerged implants in the canine mandible. J Periodontol 68:186-198
16. Donath K (1985) The diagnostic value of the new method for the study of undecalcified bones and teeth with attached soft tissue (Säge-Schliff (sawing and grinding) technique). Pathol Res Pract 179:631-633
17. Ericsson I, Nilner K, Klinge B, Glantz PO (1996) Radiographical and histological characteristics of submerged and nonsubmerged titanium implants. An experimental study in the Labrador dog. Clin Oral Implants Res 7:20-26
18. Fartash B, Arvidson K, Ericsson I (1990) Histology of tissues surrounding single crystal sapphire endosseous dental implants: An experimental study in the beagle dog. Clin Oral Implants Res 1:13-21
19. Fujii N, Kusakari H, Maeda T (1998) A histological study on tissue responses to titanium implantation in rat maxilla: The process of epithelial regeneration and bone reaction. J Periodontol 69:485-495
20. Gotfredsen K, Rostrup E, Hjorting-Hansen E, Stoltze K, Budtz-Jorgensen E (1991) Histological and histomorphometrical evaluation of tissue reactions adjacent to endosteal implants in monkeys. Clin Oral Implants Res 2:30-37
21. Guy SC, McQuade MJ, Scheidt MJ, McPherson JC, 3rd, Rossmann JA, Van Dyke TE (1993) In vitro attachment of human gingival fibroblasts to endosseous implant materials. J Periodontol 64:542-546
22. Hormia M, Kononen M (1994) Immunolocalization of fibronectin and vitronectin receptors in human gingival fibroblasts spreading on titanium surfaces. J Periodontal Res 29:146-152
23. Lindhe J, Berglundh T (1998) The interface between the mucosa and the implant. Periodontol 2000 17:47-54
24. Listgarten MA, Buser D, Steinemann SG, Donath K, Lang NP, Weber HP (1992) Light and transmission electron microscopy of the intact interfaces between non-submerged titanium-coated epoxy resin implants and bone or gingiva. J Dent Res 71:364-371
25. Masaki C, Schneider GB, Zaharias R, Seabold D, Stanford C (2005) Effects of implant surface microtopography on osteoblast gene expression. Clin Oral Implants Res 16:650-656
26. Murata M, Momose M, Okuda K, Ninagawa Y, Ueda M, Hiromasa Y (2006) Immunohistochemical localization of cytokeratin 19, involucrin and proliferating cell nuclear antigen (PCNA) in cultured human gingival epithelial sheets. J Int Acad Periodontol 8:33-38
27. Mustafa K, Silva Lopez B, Hultenby K, Wennerberg A, Arvidson K (1998) Attachment and proliferation of human oral fibroblasts to titanium surfaces blasted with TiO2 particles. A scanning electron microscopic and histomorphometric analysis. Clin Oral Implants Res 9:195-207
28. Napper CE, Drickamer K, Taylor ME (2006) Collagen binding by the mannose receptor mediated through the fibronectin type II domain. Biochem J 395:579-586
29. Paunesku T, Mittal S, Protic M, Oryhon J, Korolev SV, Joachimiak A, Woloschak GE (2001) Proliferating cell nuclear antigen (PCNA): ringmaster of the genome. Int J Radiat Biol 77:1007-1021
30. Quirynen M, Bollen CM, Eyssen H, van Steenberghe D (1994) Microbial penetration along the implant components of the Branemark system. An in vitro study. Clin Oral Implants Res 5:239-244
31. Quirynen M, van Steenberghe D (1993) Bacterial colonization of the internal part of two-stage implants. An in vivo study. Clin Oral Implants Res 4:158-161
32. Rimondini L, Fare S, Brambilla E, Felloni A, Consonni C, Brossa F, Carrassi A (1997) The effect of surface roughness on early in vivo plaque colonization on titanium. J Periodontol 68:556-562
33. Ruggeri A, Franchi M, Marini N, Trisi P, Piatelli A (1992) Supracrestal circular collagen fiber network around osseointegrated nonsubmerged titanium implants. Clin Oral Implants Res 3:169-175
34. Rupp F, Scheideler L, Olshanska N, de Wild M, Wieland M, Geis-Gerstorfer J (2006) Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces. J Biomed Mater Res A 76:323-334
35. Schroeder A, van der Zypen E, Stich H, Sutter F (1981) The reactions of bone, connective tissue, and epithelium to endosteal implants with titanium-sprayed surfaces. J Maxillofac Surg 9:15-25
36. Schwarz F, Bieling K, Bonsmann M, Latz T, Becker J (2006) Nonsurgical treatment of moderate and advanced periimplantitis lesions: A controlled clinical study. Clin Oral Investig 10:279-288
37. Schwarz F, Herten M, Sager M, Wieland M, Dard M, Becker J (2006) Bone regeneration in dehiscence-type defects at chemically modified (SLActive) and conventional SLA titanium implants: A pilot study in dogs. J Clin Periodontol 34:78-86
38. Schwarz F, Herten M, Sager M, Wieland M, Dard M, Becker J (2007) Histological and immunohistochemical analysis of initial and early osseous integration at chemically modified and conventional SLA® titanium implants. Preliminary results of a pilot study in dogs. Clin Oral Implants Res (in press)
39. Schwarz F, Sculean A, Romanos G, Herten M, Horn N, Scherbaum W, Becker J (2005) Influence of different treatment approaches on the removal of early plaque biofilms and the viability of SAOS2 osteoblasts grown on titanium implants. Clin Oral Investig 9:111-117
40. Siegrist BE, Brecx MC, Gusberti FA, Joss A, Lang NP (1991) In vivo early human dental plaque formation on different supporting substances. A scanning electron microscopic and bacteriological study. Clin Oral Implants Res 2:38-46
41. Squier CA, Collins P (1981) The relationship between soft tissue attachment, epithelial downgrowth and surface porosity. J Periodontal Res 16:434-440
42. Traini T, Assenza B, San Roman F, Thams U, Caputi S, Piattelli A (2006) Bone microvascular pattern around loaded dental implants in a canine model. Clin Oral Investig 10:151-156
43. Valenick LV, Hsia HC, Schwarzbauer JE (2005) Fibronectin fragmentation promotes alpha4beta1 integrin-mediated contraction of a fibrin-fibronectin provisional matrix. Exp Cell Res 309:48-55
44. Weber HP, Buser D, Donath K, Fiorellini JP, Doppalapudi V, Paquette DW, Williams RC (1996) Comparison of healed tissues adjacent to submerged and non-submerged unloaded titanium dental implants. A histometric study in beagle dogs. Clin Oral Implants Res 7:11-19
45. Zhao G, Schwartz Z, Wieland M, Rupp F, Geis-Gerstorfer J, Cochran DL, Boyan BD (2005) High surface energy enhances cell response to titanium substrate microstructure. J Biomed Mater Res A 74:49-58