Ranitidine and late-onset sepsis in the neonatal intensive care unit

Journal of Perinatal Medicine

Volumn 35, Issue 2, 2007, Pages 147-150

  Bianconi, Simona ^a   Gudavalli, Madhu ^a,d   Sutija, Vesna G ^a   Lopez, Anna L ^b   Barillas Arias, Lillian ^c   Ron, Nitin ^a  

^a NEW YORK METHODIST HOSPITAL   (United States)

^b International Vaccine Institute   (South Korea)

^c WEILL CORNELL MEDICAL CENTER   (United States)

^d Department of Pediatrics ^*  (United States)

Author keywords

Bacteremia; Histamine 2 antagonist; Neonatal intensive care unit; Nosocomial infections; Premature infant; Ranitidine; Sepsis

Indexed keywords

FLUCONAZOLE; GENTAMICIN; RANITIDINE; VANCOMYCIN;

BACTERIAL STRAIN; BACTERIUM CULTURE; BIRTH WEIGHT; BLOOD CULTURE; CHILD CARE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; GESTATIONAL AGE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOSPITAL ADMISSION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MEDICAL INFORMATION; MEDICAL RECORD; NEWBORN INTENSIVE CARE; OUTCOME ASSESSMENT; PARENTERAL NUTRITION; PRIORITY JOURNAL; SEPSIS;

ANTI-ULCER AGENTS; HUMANS; INFANT, NEWBORN; RANITIDINE; RETROSPECTIVE STUDIES; RISK FACTORS; SEPSIS;

EID: 33847692435     PISSN: 03005577     EISSN: 16193997     Source Type: Journal    
DOI: 10.1515/JPM.2007.017     Document Type: Conference Paper

References (16)

1. Beck-Sague CM, P Azimi, SN Fonseca, RS Baltimore, DA Powell, LA Bland, et al.: Bloodstream infections in neonatal intensive care unit patients: results of a multicenter study. Pediatr Infect Dis J 13 (1994) 1110
2. Cloherty JP, EC Eichenwald, AR Stark (eds): Manual of Neonatal Care. Lippincott Williams and Wilkins, Philadelphia 2004
3. Cothran DS, SM Borowitz, JL Sutphen, SM Dudley, LG Donowitz: Alteration of normal gastric flora in neonates receiving ranitidine. J Perinatol 17 (1997) 383
4. Dinsmore JE, RJ Jackson, SD Smith: The protective role of gastric acidity in neonatal bacterial translocation. J Pediatr Surg 32 (1997) 1014
5. Graham PL, MD Begg, E Larson, P Della-Latta, A Allen, L Saiman: Risk factors for late onset gram-negative sepsis in low birth weight infants hospitalized in the neonatal intensive care unit. Pediatr Infect Dis J 25 (2006) 113
6. Guillet R, BJ Stoll, CM Cotton, M Gantz, S McDonald, WK Poole, et al.: Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in very low birth weight infants. Pediatrics 117 (2006) e137
7. Hanisch EW, A Encke, F Naujoks, J Windolf: A randomized, double-blind trial for stress ulcer prophylaxis shows no evidence of increased pneumonia. Am J Surg 176 (1998) 453
8. Jiang JH, NC Chiu, HA Kao, CH Hsu, HY Hung, JH Chang, et al.: Neonatal sepsis in the intensive care unit: characteristis of early verus late onset. J Microbiol Immul Infect/Chung Hua Min Kuo Hsiao Erh Ko I Hsueh Hui Tsa Chih 37 (2004) 301
9. Kuusela AL, T Ruuska, R Karikoski, P Laippala, RS Ikonen, M Janas, et al.: A randomized, controlled study of prophylactic ranitidine in preventing stress-induced gastric mucosal lesions in neonatal intensive care unit patients. Crit Care Med 25 (1997) 346
10. Lukacs SL, KC Shoendorf, A Schuchat: Trends in sepsis related neonatal mortality in the USA, 1985-1998. Pediatr Infect Dis J 23 (2004) 599
11. Messori A, S Trippoli, M Vaiani, M Gorini, A Corrado: Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomized controlled trials. Br Med J 321 (2000) 1103
12. Neu J, H Bernstein: Update on host defense and immunonutrients In: Berseth CL: Clinics In Perinatology, Recent Advances in Neonatal Gastroenterology. Saunders 29 (2002) 41
13. Stoll BJ, N Hansen, AA Fanaroff, LL Wright, WA Carlo, RA Ehrenkranz, et al.: Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 110 (2002) 285
14. Thorens J, F Froehlich, W Schwizer, E Saraga, L Bille, K Gyr, et al.: Bacterial overgrowth during treatment with omeprazole compared with cimetidine: a prospective randomized double blind study. Gut 39 (1996) 54
15. Weber JR, K Angstwurm, T Rosenkranz, U Lindauer, W Buerger, K Einhaeupl, et al.: Histamine receptor antagonist inhibits leukocyte rolling in pial vessels in the early phase of bacterial meningitis in rats. Neurosci Lett 226 (1997) 17
16. Yamaki K, H Thorlacius, X Xie, L Lindbom, P Hedqvist, J Raud: Characteristics of histamine-induced leukocyte rolling in the undisturbed microcirculation of the rat mesentery. Br J Pharmacology 123 (1998) 390