The production of hypericins in two selected Hypericum perforatum shoot cultures is related to differences in black gland structure

Plant Physiology and Biochemistry

Volumn 45, Issue 1, 2007, Pages 24-32

  Kornfeld, Ari ^a   Kaufman, Peter B ^b,d   Lu, Casey R ^a   Gibson, Donna M ^c   Bolling, Steven F ^b,d   Warber, Sara L ^d   Chang, Soo Chul ^e   Kirakosyan, Ara ^b,d  

^a HUMBOLDT STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c ROBERT W HOLLEY CENTER FOR AGRICULTURE AND HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e Yonsei University   (South Korea)

Author keywords

Black glands or dark nodules; Hypericins; Hypericum perforatum; Shoot cultures; Ultrastructural analysis

Indexed keywords

DRUG DERIVATIVE; HYPERICIN; PERYLENE;

ARTICLE; CELL CULTURE; HYPERICUM; METABOLISM; PLANT; PLANT LEAF; SCANNING ELECTRON MICROSCOPY; ULTRASTRUCTURE;

CELLS, CULTURED; HYPERICUM; MICROSCOPY, ELECTRON, SCANNING; PERYLENE; PLANT LEAVES; PLANT SHOOTS;

HYPERICUM PERFORATUM;

EID: 33847689745     PISSN: 09819428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plaphy.2006.12.009     Document Type: Article

References (22)

1. Briskin D.P., and Gawienowski M. Differential effects of light and nitrogen on production of hypericins and leaf glands in Hypericum perforatum. Plant Physiology Biochemistry 39 (2001) 1075-1081
2. Butterweck V., Lieflander-Wulf U., Winterhoff H., and Nahrstedt A. Plasma levels of hypericin in presence of procyanidin B2 and hyperoside: a pharmacokinetic study in rats. Planta Medica 69 (2003) 189-192
3. o regenerants in Hypericum perforatum L. Acta Biotechnologia 12 (1992) 445-452
4. Cellárová E., Daxnerová Z., Kimáková K., and Halusková J. The variability of the hypericin content in the regenerants of Hypericum perforatum. Acta Biotechnologia 14 (1994) 267-274
5. Cellárová E., Kimakova K., Daxnerova Z., and Martonfi P. Hypericum perforatum (St. John's Wort): In vitro culture and production of hypericin and other secondary metabolites. In: Bajaj Y.P.S. (Ed). Biotechnology in Agriculture and Forestry vol. 33 (1995), Medicinal and Aromatic Plants VIII. Springer-Verlag, Berlin 261-275
6. Ciccarelli D., Andreucci A., and Pagni A.M. The "black nodules" of Hypericum perforatum L. subsp. perforatum: morphological, anatomical and histochemical studies during the course of ontogenesis. Israel Journal of Plant Sciences 49 (2001) 33-40
7. Ciccarelli D., Andreucci A., and Pagni A.M. Translucent glands and secretory canals in Hypericum perforatum L. (Hypericaceae): morphological, anatomical and histochemical studies during the course of ontogenesis. Annals of Botany 88 (2001) 637-644
8. Curtis J.D., and Lersten N.R. Internal secretory structures in Hypericum (Clusiaceae): H. perforatum L. and H. balearicum L. The New Phytologist 114 (1990) 571-580
9. Fields P.G., Arnason J.T., and Fulcher R.G. The spectral properties of Hypericum perforatum leaves: the implications for its photoactivated defences. Canadian Journal of Botany 68 (1990) 1166-1170
10. Fornasiero R.B., Bianchi A., and Pinetti A. Anatomical and ultrastructural observations in Hypericum perforatum L. leaves, Journal of Herbs. Spices & Medicinal Plants 5 (1998) 21-33
11. Hang Y., Lu Y., Zhou Y., Guo K., Shi Y., The biological characteristics and property of wild and cultivated plants of Hypericum perforatum L., Journal of Plant Resources and Environment 11 (2002) 20-23 (in Chinese; English abstract from BIOSIS Previews 2002.)
12. Kirakosyan A., Gibson D.M., and Sirvent T. A comparative study of Hypericum perforatum plants as sources of hypericins and hyperforins. Journal of Herbs Spices and Medicinal Plants 10 (2003) 73-88
13. Kirakosyan A., Sirvent T.M., Gibson D.M., and Kaufman P.B. The production of hypericins and hyperforin by in vitro cultures of Hypericum perforatum. Biotechnology and Applied Biochemistry 39 (2004) 71-81
14. Kosuth J., Koperdakova J., Tolonen A., Hohtola A., and Cellárová E. The content of hypericins and phloroglucinols in Hypericum perforatum L. seedlings at early stage of development. Plant Science 165 (2003) 515-521
15. Liu W., Lu H., and Hu Z.H. Ultrastructure of the multicellular nodules in Hypericum perforatum leaves. Acta Botanica Sinica 44 (2002) 649-656
16. Onelli E., Rivetta A., Giorgi A., Bignami M., Cocucci M., and Patrignani G. Ultrastructural studies on the developing secretory nodules of Hypericum perforatum. Flora 197 (2002) 92-102
17. Pasqua G., Avato P., Monacelli B., Santamaria A., and Argentieri M. Metabolites in cell suspension cultures, calli, and in vitro regenerated organs of Hypericum perforatum cv. Topas. Plant Science 165 (2003) 977-982
18. Sirvent T., and Gibson D. Rapid isocratic analysis of hypericins. Journal of Liquid Chromatography 23 (2000) 251-259
19. Southwell I.A., and Campbell M.H. Hypericin content variation in Hypericum perforatum in Australia. Phytochemistry 30 (1991) 475-478
20. Tekel'ová D., Repcák M., Zemková E., and Toth J. Quantitative changes of dianthrones, hyperforin and flavonoids content in the flower ontogenesis of Hypericum perforatum. Planta Medica 66 (2000) 778-780
21. Walker L., Sirvent T., Gibson D., and Vance N. Regional differences in hypericin and pseudohypericin concentrations and five morphological traits among Hypericum perforatum plants in the northwestern United States. Canadian Journal of Botany 79 (2001) 1248-1255
22. Zdunek K., and Alfermann W. Initiation of shoot organ cultures of Hypericum perforatum and formation of hypericin derivatives. Planta Medica 58 (1992) 621-622