A survey of the management of neutropenic fever in oncology units in the UK

International Journal of Antimicrobial Agents

Volumn 29, Issue 4, 2007, Pages 430-433

  Ziglam, H M ^a   Gelly, K ^b   Olver, W ^b  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Adult; Antibiotic prophylaxis; Antibiotic therapy; Fever; Neutropenia

Indexed keywords

CARBAPENEM; CASPOFUNGIN; CEFTAZIDIME; CIPROFLOXACIN; FLUCONAZOLE; GENTAMICIN; IMIPENEM; ITRACONAZOLE; MEROPENEM; OFLOXACIN; PIPERACILLIN; TAZOBACTAM; TEICOPLANIN; VANCOMYCIN; VORICONAZOLE;

ANTIMICROBIAL THERAPY; ARTICLE; CONTROLLED STUDY; EMPIRICISM; FEBRILE NEUTROPENIA; HUMAN; ONCOLOGY; ONCOLOGY WARD; PRIORITY JOURNAL; QUESTIONNAIRE; TREATMENT DURATION; UNITED KINGDOM;

ADMINISTRATION, ORAL; ANTI-INFECTIVE AGENTS; ANTIBIOTIC PROPHYLAXIS; FEVER; GREAT BRITAIN; HEALTH SURVEYS; HOSPITAL UNITS; HUMANS; INFECTION; MEDICAL ONCOLOGY; NEOPLASMS; NEUTROPENIA; QUESTIONNAIRES;

EID: 33847684851     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.12.009     Document Type: Article

References (22)

1. Schimpff S.C. Overview of empiric antibiotic therapy for the febrile neutropenic patient. Rev Infect Dis 7 Suppl. 4 (1985) S734-S740
2. Masaoka T. Management of fever of unknown origin in the neutropenic patient: the Japanese experience. Int J Hematol 68 Suppl. 1 (1998) S9-S11
3. Proceedings of the consensus meeting: Evidence-Based Recommendations on the Management of Febrile Neutropenia in Japan. Honolulu, Hawaii, 8-9 March 2003. Clin Infect Dis 2004;39(Suppl. 1):S1-69
4. Ziglam H.M., Gelly K.J., and Olver W.J. A survey of the antibiotic treatment of febrile neutropenia in haematology units in the United Kingdom. Clin Lab Haematol 27 (2005) 374-378
5. Furno P., Bucaneve G., and Del Favero A. Monotherapy or aminoglycoside-containing combinations for empirical antibiotic treatment of febrile neutropenic patients: a meta-analysis. Lancet Infect Dis 2 (2002) 231-242
6. Paul M., Soares-Weiser K., and Leibovici L. Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for fever with neutropenia: systematic review and meta-analysis. BMJ 326 (2003) 1111
7. Rolston K.V., Berkey P., Bodey G.P., et al. A comparison of imipenem to ceftazidime with or without amikacin as empiric therapy in febrile neutropenic patients. Arch Intern Med 152 (1992) 283-291
8. Schimpff S.C., Gaya H., Klastersky J., Tattersall M.H., and Zinner S.H. Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. The EORTC International Antimicrobial Therapy Project Group. J Infect Dis 137 (1978) 14-29
9. Safdar N., Handelsman J., and Maki D.G. Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia? A meta-analysis. Lancet Infect Dis 4 (2004) 519-527
10. Paul M., Borok S., Fraser A., Vidal L., and Leibovici L. Empirical antibiotics against Gram-positive infections for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials. J Antimicrob Chemother 55 (2005) 436-444
11. Hughes W.T., Armstrong D., Bodey G.P., et al. 2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer. Clin Infect Dis 34 (2002) 730-751
12. Klastersky J., Paesmans M., Rubenstein E.B., et al. The Multinational Association for Supportive Care in Cancer risk index: a multinational scoring system for identifying low-risk febrile neutropenic cancer patients. J Clin Oncol 18 (2000) 3038-3051
13. Vidal L., Paul M., Ben-Dor I., Pokroy E., Soares-Weiser K., and Leibovici L. Oral versus intravenous antibiotic treatment for febrile neutropenia in cancer patients. Cochrane Database Syst Rev (2004) CD003992
14. Cruciani M., Rampazzo R., Malena M., et al. Prophylaxis with fluoroquinolones for bacterial infections in neutropenic patients: a meta-analysis. Clin Infect Dis 23 (1996) 795-805
15. Engels E.A., Lau J., and Barza M. Efficacy of quinolone prophylaxis in neutropenic cancer patients: a meta-analysis. J Clin Oncol 16 (1998) 1179-1187
16. Gafter-Gvili A., Fraser A., Paul M., and Leibovici L. Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients. Ann Intern Med 142 (2005) 979-995
17. Hori S., Sunley R., Tami A., and Grundmann H. The Nottingham Staphylococcus aureus Population Study: prevalence of MRSA among the elderly in a university hospital. J Hosp Infect 50 (2002) 25-29
18. Kern W.V., Klose K., Jellen-Ritter A.S., et al. Fluoroquinolone resistance of Escherichia coli at a cancer center: epidemiologic evolution and effects of discontinuing prophylactic fluoroquinolone use in neutropenic patients with leukemia. Eur J Clin Microbiol Infect Dis 24 (2005) 111-118
19. Walsh T.J., Finberg R.W., Arndt C., et al. Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group. N Engl J Med 340 (1999) 764-771
20. Walsh T.J., Teppler H., Donowitz G.R., et al. Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia. N Engl J Med 351 (2004) 1391-1402
21. Bow E.J., Laverdiere M., Lussier N., Rotstein C., Cheang M.S., and Ioannou S. Antifungal prophylaxis for severely neutropenic chemotherapy recipients: a meta analysis of randomized-controlled clinical trials. Cancer 94 (2002) 3230-3246
22. Kanda Y., Yamamoto R., Chizuka A., et al. Prophylactic action of oral fluconazole against fungal infection in neutropenic patients. A meta-analysis of 16 randomized, controlled trials. Cancer 89 (2000) 1611-1625