Spurious urine excretion drug profile in the horse due to bedding contamination and drug recycling: The case of meclofenamic acid

Journal of Veterinary Pharmacology and Therapeutics

Volumn 30, Issue 2, 2007, Pages 179-184

  Popot, M A ^a,c   Menaut, L ^a   Boyer, S ^a   Bonnaire, Y ^a   Toutain, P L ^b  

^a LCH   (France)

^b CNRS   (France)

^c Laboratoire des Courses Hippiques   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MECLOFENAMIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTAMINATION; DRUG CLEARANCE; DRUG DETERMINATION; DRUG EXCRETION; FEMALE; GAS CHROMATOGRAPHY; HORSE; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; URINALYSIS; URINARY EXCRETION;

ANIMAL HUSBANDRY; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BEDDING AND LINENS; DOPING IN SPORTS; FEMALE; HORSES; INFUSIONS, INTRAVENOUS; MALE; MECLOFENAMIC ACID; URINALYSIS;

EQUIDAE;

EID: 33847656948     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2007.00835.x     Document Type: Article

References (9)

1. Harkins, J.D., Woods, W.E., Lehner, A.F., Fisher, M. & Tobin, T. (2001) Clenbuterol in the horse: urinary concentrations determined by ELISA and GC/MS after clinical doses. Journal of Veterinary Pharmacology and Therapeutics, 24, 7-14.
2. Johansson, I.M., Anlér, E.L. & Bondesson, U. (1986) Isolation of meclofenamic acid and two metabolites from equine urine - a comparison between horse and man. Journal of Pharmaceutical and Biomedical Analysis, 4, 171-179.
3. Johansson, I.M., Kallings, P. & Hammarlund-udenaes, M. (1991) Studies of meclofenamic acid and two metabolites in horses - pharmacokinetics and effects on exercise tolerance. Journal of Veterinary Pharmacology and Therapeutics, 14, 235-242.
4. Lees, P., Taylor, J.B., Higgins, A.J. & Sharma, S.C. (1986) Phenylbutazone and oxyphenbutazone distribution into tissue fluids in the horse. Journal of Veterinary Pharmacology and Therapeutics, 9, 204-212.
5. Norgren, A., Invast-Larsson, C., Kallings, P., Fredriksson, E. & Bondesson, U. (2000) Contamination and urinary of flunixin after repeated administration in the horse. Proceedings of the 14th International Conference of Racing Analysts and Veterinarians, pp. 377-380, Cambridge.
6. Popot, M.A., Michel, S., Garcia, P. & Bonnaire, Y. (2005) Approaches to the detection of drugs in horse faeces. Proceedings of the 15th International Conference of Racing Analysts and Veterinarians, pp. 481-485, Dubai.
7. Schubert, B., Johansson, I.M. & Eklund, M.L. (1985) Analysis and pharmacokinetic of meclofenamic acid in horses. Proceedings of the 6th International Conference of Racing Analysts and Veterinarians, pp. 363-367, Hong Kong.
8. Snow D.H., Baxter P. & Whiting B. (1981) The pharmacokinetics of meclofenamic acid in the horse. Journal of Veterinary Pharmacology and Therapeutics, 4, 147-156.
9. Wennerlund, I., Ingvast-Larsson, C., Kallings, P., Fredriksson, E. & Bondesson, U. (2000) Pharmacokinetics and urinary excretion of naproxen after repeated oral administration. Proceedings of the 14th International Conference of Racing Analysts and Veterinarians, pp. 195-200, Cambridge.