Effects of topical administration of 12-methyl tetradecanoic acid (12-MTA) on the development of corneal angiogenesis

Angiogenesis

Volumn 10, Issue 1, 2007, Pages 47-54

  Cole, Nerida ^a,b   Hume, Emma B H ^a,b,c   Jalbert, Isabelle ^a,b,c   Kumar Vijay, Ajay ^b,c   Krishnan, Ravi ^d   Willcox, Mark D P ^a,b,c  

^a BRIEN HOLDEN VISION INSTITUTE   (Australia)

^b VISION COOPERATIVE RESEARCH CENTRE   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d QUEEN ELIZABETH HOSPITAL   (Australia)

Author keywords

12 Methyl tetradecanoic acid; Alkali injury; Angiogenesis; Cornea; Pseudomonas aeruginosa

Indexed keywords

12 METHYLTETRADECANOIC ACID; ALKALI; ANGIOGENESIS INHIBITOR; DEXAMETHASONE; MYRISTIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CORNEA INJURY; CORNEA VASCULARIZATION; EPITHELIUM; GROWTH; KERATITIS; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; THERAPY EFFECT;

ADMINISTRATION, TOPICAL; ANGIOGENESIS INHIBITORS; ANIMALS; CORNEA; CORNEAL NEOVASCULARIZATION; DEXAMETHASONE; DISEASE MODELS, ANIMAL; EYE BURNS; EYE INFECTIONS, BACTERIAL; FATTY ACIDS; GLUCOCORTICOIDS; MALE; MICE; MICE, INBRED BALB C; PSEUDOMONAS INFECTIONS; SODIUM HYDROXIDE;

PSEUDOMONAS AERUGINOSA;

EID: 33847654375     PISSN: 09696970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10456-007-9063-3     Document Type: Article

References (19)

1. Lee P, Wang CC, Adamis AP (1998) Ocular neovascularization: an epidemiologic review. Surv Ophthalmol 43:245-269
2. Ormerod LD, Abelson MB, Kenyon KR (1989) Standard models of corneal injury using alkali-immersed filter discs. Invest Ophthalmol Vis Sci 30:2148-2153
3. Lee EJ, Truong NT, Mendoza MN, Fleiszig SMJ (2003) A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics. Curr Eye Res 27:289-299
4. Kuchle M, Cursiefen C, Nguyen NX, Langenbucher A, Seitz B, Wenkel H, Martus P, Naumann GO (2002) Risk factors for corneal allograft rejection: intermediate results of a prospective normal-risk keratoplasty study. Graefes Arch Clin Exp Ophthalmol 240:580-584
5. Krishnan R, Cole N, Jalbert I, Hume EBH, Willcox MDP (2004) Effect of topical 12-methyltetradecanoic acid during Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci 45:4957
6. Planck SR, Rich LF, Ansel JC, Huang XN, Rosenbaum JT (1997) Trauma and alkali burns induce distinct patterns of cytokine gene expression in the rat cornea. Ocular Immunol Inflamm 5:95-100
7. Cole N, Willcox MDP, Fleiszig SMJ, Stapleton FJ, Bao S, Tout S, Husband AJ (1998) Different strains of Pseudomonas aeruginosa isolated from ocular infections or inflammation display distinct corneal pathologies in an animal model. Curr Eye Res 17:730-735
8. Cole N, Krockenberger M, Stapleton F, Khan S, Hume EB, Husband AJ, Willcox MDP (2003) Experimental Pseudomonas aeruginosa keratitis in Interleukin-10 gene knockout mice. Infect Immun 71:1328-1336
9. Wagoner MD (1997) Chemical injuries of the eye: current concepts in pathophysiology and therapy. Surv Ophthalmol 41:275-313
10. Ozturk F, Kurt E, Cerci M, Emiroglu L, Inan U, Turker M, Ilker S (2000) The effect of propolis extract in experimental chemical corneal injury. Ophthalmol Res 32:13-18
11. Stroncek DF, Matthews CL, Follmann D, Leitman SF (2000) Kinetics of G-CSF-induced granulocyte mobilization in healthy subjects: effects of route of administration and addition of dexamethasone. Transfusion 42:597-602
12. Konig T, Schuberth HJ, Leibold W, Zerbe H (2006) Dexamethasone depresses the expression of L-selectin but not the in vivo migration of bovine neutrophils into the uterus. Theriogenology 65:1227-1241
13. Chang LC, Madsen SA, Toelboell T, Weber PS, Burton JL (2004) Effects of glucocorticoids on Fas gene expression in bovine blood neutrophils. J Endocrinol 183:569-583
14. Hazlett LD (2004) Corneal response to Pseudomonas aeruginosa infection. Prog Ret Eye Res 23:1-30
15. Conners MS, Urbano F, Vafeas C, Stoltz RA, Dunn MW, Schwartzman ML (1997) Alkali burn-induced synthesis of inflammatory eicosanoids in rabbit corneal epithelium. Invest Ophthalmol Vis Sci 38:1963-1971
16. Bazan HE (2005) Cellular and molecular events in corneal wound healing: significance of lipid signalling. Exp Eye Res 80:453-463
17. Kernacki KA, Berk RS (1994) Characterization of the inflammatory response induced by corneal infection with Pseudomonas aeruginosa. J Ocular Pharmacol 10:281-288
18. Kernacki KA, Berk RS (1995) Characterization of arachidonic acid metabolism and the polymorphonuclear leukocyte response in mice infected intracorneally with Pseudomonas aeruginosa. Invest Ophthalmol Vis Sci 36:16-23
19. Wright KC, Yang P, Van Pelt CS, Hicks ME, Collin P, Newman RA (2005) Evaluation of targeted arterial delivery of the branched chain fatty acid 12-methyltetradecanoic acid as a novel therapy for solid tumors. J Exp Therap Oncol 5:55-68