-
1
-
-
23244437569
-
Osteoarthritis : An overview of the disease and its treatment strategies
-
SARZI-PUTTINI P., CIMMINO M.A., SCARPA R., CAPORALI R., PARAZZINI F. et al. - Osteoarthritis : an overview of the disease and its treatment strategies. Semin.ArthritisRheum., 2005, 35 (1 Suppl 1), 1-10.
-
(2005)
Semin.ArthritisRheum
, vol.35
, Issue.1 SUPPL. 1
, pp. 1-10
-
-
SARZI-PUTTINI, P.1
CIMMINO, M.A.2
SCARPA, R.3
CAPORALI, R.4
PARAZZINI, F.5
-
2
-
-
18244385249
-
Osteoarthritis : An Untreatable Disease ?
-
WIELAND H.A., MICHAELIS M., KIRSCHBAUM B.J., RUDOLPHI K.A. - Osteoarthritis : An Untreatable Disease ? Nat.Rev.Drug.Discov., 2005, 4, 331-344.
-
(2005)
Nat.Rev.Drug.Discov
, vol.4
, pp. 331-344
-
-
WIELAND, H.A.1
MICHAELIS, M.2
KIRSCHBAUM, B.J.3
RUDOLPHI, K.A.4
-
3
-
-
5044252210
-
Obesity as a risk factor for osteoarthritis : Mechanical versus metabolic
-
EATON C.B. - Obesity as a risk factor for osteoarthritis : mechanical versus metabolic. Med.Health.RI., 2004, 87, 201-204.
-
(2004)
Med.Health.RI
, vol.87
, pp. 201-204
-
-
EATON, C.B.1
-
4
-
-
0029682257
-
The association of obesity with osteoarthritis of the hand and knee in women : A twin study
-
CICUTTINI F.M., BAKER J.R., SPECTOR T.D. - The association of obesity with osteoarthritis of the hand and knee in women : a twin study. J.Rheumatol., 1996, 23, 1221-1226.
-
(1996)
J.Rheumatol
, vol.23
, pp. 1221-1226
-
-
CICUTTINI, F.M.1
BAKER, J.R.2
SPECTOR, T.D.3
-
5
-
-
0031732077
-
Change in body fat, but not body weight or metabolic correlates of obesity, is related to symptomatic relief of obese patients with knee osteoarthritis after a weight control program
-
TODA Y., TODA C., TAKEMURA S., WADA T., MORIMOTO T. et al. - Change in body fat, but not body weight or metabolic correlates of obesity, is related to symptomatic relief of obese patients with knee osteoarthritis after a weight control program. J.Rheumatol., 1998, 25, 2181-2186.
-
(1998)
J.Rheumatol
, vol.25
, pp. 2181-2186
-
-
TODA, Y.1
TODA, C.2
TAKEMURA, S.3
WADA, T.4
MORIMOTO, T.5
-
6
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
ZHANG Y., PROENCA R., MAFFEI M., BARONE M., LEOPOLD L. et al. - Positional cloning of the mouse obese gene and its human homologue. Nature, 1994, 372, 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
ZHANG, Y.1
PROENCA, R.2
MAFFEI, M.3
BARONE, M.4
LEOPOLD, L.5
-
8
-
-
6944237757
-
Adipokines : Inflammation and the pleiotropic role of white adipose tissue
-
TRAYHURN P., WOOD I.S. - Adipokines : inflammation and the pleiotropic role of white adipose tissue. Br.J.Nutr., 2004, 92, 347-355.
-
(2004)
Br.J.Nutr
, vol.92
, pp. 347-355
-
-
TRAYHURN, P.1
WOOD, I.S.2
-
9
-
-
2342571612
-
Development of novel therapeutics to treat joint diseases - what can be learned from other disease areas ?
-
LARK M., BLAKE S. - Development of novel therapeutics to treat joint diseases - what can be learned from other disease areas ? Curr.Opin.Pharmacol., 2004, 4, 273-275.
-
(2004)
Curr.Opin.Pharmacol
, vol.4
, pp. 273-275
-
-
LARK, M.1
BLAKE, S.2
-
10
-
-
0035462008
-
The bone and joint decade : A catalyst for progress
-
HARRIS E.D. - The bone and joint decade : a catalyst for progress. ArthritisRheum., 2001, 44, 1969-1970.
-
(2001)
ArthritisRheum
, vol.44
, pp. 1969-1970
-
-
HARRIS, E.D.1
-
11
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
WEISBERG S.P., MCCANN D., DESAI M., ROSENBAUM M., LEIBEL R.L. et al. - Obesity is associated with macrophage accumulation in adipose tissue. J.Clin.Invest., 2003, 112, 1796-1808.
-
(2003)
J.Clin.Invest
, vol.112
, pp. 1796-1808
-
-
WEISBERG, S.P.1
MCCANN, D.2
DESAI, M.3
ROSENBAUM, M.4
LEIBEL, R.L.5
-
12
-
-
0028091785
-
Regional adiposity and morbidity
-
KISSEBAH A.H., KRAKOWER G.R. - Regional adiposity and morbidity. Physiol.Rev., 1994, 74, 761-811.
-
(1994)
Physiol.Rev
, vol.74
, pp. 761-811
-
-
KISSEBAH, A.H.1
KRAKOWER, G.R.2
-
13
-
-
29744458790
-
Adipose tissue as source and target for novel therapies
-
KLEIN J., PERWITZ N., KRAUS D., FASSHAUER M. - Adipose tissue as source and target for novel therapies. Trends.Endocrinol.Metab., 2006, 17, 26-32.
-
(2006)
Trends.Endocrinol.Metab
, vol.17
, pp. 26-32
-
-
KLEIN, J.1
PERWITZ, N.2
KRAUS, D.3
FASSHAUER, M.4
-
14
-
-
27744497128
-
Leptin : Structure, function and biology
-
ZHANG F., CHEN Y., HEIMAN M., DIMARCHI R. - Leptin : structure, function and biology. Vitam.Horm., 2005, 71, 345-372.
-
(2005)
Vitam.Horm
, vol.71
, pp. 345-372
-
-
ZHANG, F.1
CHEN, Y.2
HEIMAN, M.3
DIMARCHI, R.4
-
15
-
-
0029980285
-
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcrit 1)
-
MAEDA K., OKUBO K., SHIMOMURA I., FUNAHASHI T., MATSUZAWA Y. et al. - cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcrit 1). Biochem.Biophys.Res.Commun., 1996, 221, 286-289.
-
(1996)
Biochem.Biophys.Res.Commun
, vol.221
, pp. 286-289
-
-
MAEDA, K.1
OKUBO, K.2
SHIMOMURA, I.3
FUNAHASHI, T.4
MATSUZAWA, Y.5
-
16
-
-
23844511555
-
Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy
-
TAN G.D., DEBARD C., FUNAHASHI T., HUMPHREYS S.M., MATSUZAWA Y et al. - Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy. Diabetologia, 2005, 48, 1585-1589.
-
(2005)
Diabetologia
, vol.48
, pp. 1585-1589
-
-
TAN, G.D.1
DEBARD, C.2
FUNAHASHI, T.3
HUMPHREYS, S.M.4
MATSUZAWA, Y.5
-
17
-
-
28444488589
-
Leptin : Adiponectin ratio as an atherosclerotic index in patients with type 2 diabetes : relationship of the index to carotid intima-media thickness
-
KOTANI K., SAKANE N., SAIGA K., KUROZAWA Y. - Leptin : adiponectin ratio as an atherosclerotic index in patients with type 2 diabetes : relationship of the index to carotid intima-media thickness. Diabetologia, 2005, 48, 2684-2686.
-
(2005)
Diabetologia
, vol.48
, pp. 2684-2686
-
-
KOTANI, K.1
SAKANE, N.2
SAIGA, K.3
KUROZAWA, Y.4
-
18
-
-
17844392652
-
Resistin, an adipokine with potent proinflammatory properties
-
BOKAREWA M., NAGAEV I., DAHLBERG L., SMITH U., TARKOWSKI A. - Resistin, an adipokine with potent proinflammatory properties. J.Immunol., 2005, 174, 5789-5795.
-
(2005)
J.Immunol
, vol.174
, pp. 5789-5795
-
-
BOKAREWA, M.1
NAGAEV, I.2
DAHLBERG, L.3
SMITH, U.4
TARKOWSKI, A.5
-
19
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
STEPPAN C., BAILEY S., BHAT S., BROWN E., BANERJEE R. et al. - The hormone resistin links obesity to diabetes. Nature, 2001, 409, 307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
STEPPAN, C.1
BAILEY, S.2
BHAT, S.3
BROWN, E.4
BANERJEE, R.5
-
20
-
-
15744399190
-
An inflammatory cascade leading to hyperresistinemia in humans
-
LEHRKE M., REILLY M., MILLINGTON S., IQBAL N., RADER D. et al. - An inflammatory cascade leading to hyperresistinemia in humans. Plos.Med., 2004, 1, 161-168.
-
(2004)
Plos.Med
, vol.1
, pp. 161-168
-
-
LEHRKE, M.1
REILLY, M.2
MILLINGTON, S.3
IQBAL, N.4
RADER, D.5
-
21
-
-
0035820271
-
Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism
-
APSDEN R., SCHEVEN B.A., HUTCHISON J. - Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism. Lancet, 2001, 357, 1118-1120.
-
(2001)
Lancet
, vol.357
, pp. 1118-1120
-
-
APSDEN, R.1
SCHEVEN, B.A.2
HUTCHISON, J.3
-
22
-
-
33744923195
-
Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production
-
PRESLE N., POTTIE P., DUMOND H., GUILLAUME M., LAPICQUE F. et al. - Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production. OsteoarthritisCartilage, 2006, 14, 690-695.
-
(2006)
OsteoarthritisCartilage
, vol.14
, pp. 690-695
-
-
PRESLE, N.1
POTTIE, P.2
DUMOND, H.3
GUILLAUME, M.4
LAPICQUE, F.5
-
23
-
-
0242552925
-
Evidence for a key role of leptin in osteoarthritis
-
DUMOND H., PRESLE N., TERLAIN B., MAINARD D., LOEUILLE D. et al. - Evidence for a key role of leptin in osteoarthritis. ArthritisRheum., 2003, 48, 3118-3129.
-
(2003)
ArthritisRheum
, vol.48
, pp. 3118-3129
-
-
DUMOND, H.1
PRESLE, N.2
TERLAIN, B.3
MAINARD, D.4
LOEUILLE, D.5
-
24
-
-
0035860185
-
Human articular chondrocytes express functional leptin receptors
-
FIGENSCHAU Y., KNUTSEN G., SHAHAZEYDI S., JOHANSEN O., SVEINBJORNSSON B. - Human articular chondrocytes express functional leptin receptors. Biochem.Biophys.Res.Commun., 2001, 287, 190-197.
-
(2001)
Biochem.Biophys.Res.Commun
, vol.287
, pp. 190-197
-
-
FIGENSCHAU, Y.1
KNUTSEN, G.2
SHAHAZEYDI, S.3
JOHANSEN, O.4
SVEINBJORNSSON, B.5
-
25
-
-
0035794211
-
Modulation of circulating leptin levels by its soluble receptor
-
HUANG L., WANG Z., LI C. - Modulation of circulating leptin levels by its soluble receptor. J.Biol.Chem., 2001, 276, 6343-6349.
-
(2001)
J.Biol.Chem
, vol.276
, pp. 6343-6349
-
-
HUANG, L.1
WANG, Z.2
LI, C.3
-
26
-
-
0141816765
-
Adipocytokines in synovial fluid
-
SCHAFFLER A., EHLING A., NEUMANN E., HERFARTH H., TARNER I. et al. - Adipocytokines in synovial fluid. JAMA, 2003, 290, 1709-1710.
-
(2003)
JAMA
, vol.290
, pp. 1709-1710
-
-
SCHAFFLER, A.1
EHLING, A.2
NEUMANN, E.3
HERFARTH, H.4
TARNER, I.5
-
27
-
-
23644441936
-
Osteoarthritis : A metabolic disease induced by local abnormal leptin activity ?
-
LAJEUNESSE D., PELLETIER J.P., MARTEL- PELLETIER J. - Osteoarthritis : a metabolic disease induced by local abnormal leptin activity ? Curr.Rheumatol.Rep., 2005, 7, 79-81.
-
(2005)
Curr.Rheumatol.Rep
, vol.7
, pp. 79-81
-
-
LAJEUNESSE, D.1
PELLETIER, J.P.2
MARTEL- PELLETIER, J.3
-
28
-
-
30344486078
-
Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes : Synergistic effect of leptin with interleukin-1
-
OTERO M., LAGO R., LAGO F., REINO J.J., GUALILLO O. - Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes : synergistic effect of leptin with interleukin-1. ArthritisRes.Ther., 2005, 7, R581-R591.
-
(2005)
ArthritisRes.Ther
, vol.7
-
-
OTERO, M.1
LAGO, R.2
LAGO, F.3
REINO, J.J.4
GUALILLO, O.5
-
29
-
-
33645380810
-
Leptin : A metabolic hormone that functions like a proinflammatory adipokine
-
OTERO M., LAGO R., GOMEZ R., LAGO F., GOMEZ-REINO J.J. et al. - Leptin : a metabolic hormone that functions like a proinflammatory adipokine. DrugNews.Perspect., 2006, 19, 21-26.
-
(2006)
DrugNews.Perspect
, vol.19
, pp. 21-26
-
-
OTERO, M.1
LAGO, R.2
GOMEZ, R.3
LAGO, F.4
GOMEZ-REINO, J.J.5
-
30
-
-
2342518168
-
The complex effects of leptin on bone metabolism through multiple pathways
-
THOMAS T. - The complex effects of leptin on bone metabolism through multiple pathways. Curr.Opin.Pharmacol., 2004, 4, 295-300.
-
(2004)
Curr.Opin.Pharmacol
, vol.4
, pp. 295-300
-
-
THOMAS, T.1
-
31
-
-
18044394024
-
Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast
-
OSHIMA K., NAMPEI A., MATSUDA M., IWAKI M., FUKUHARA A., et al. - Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast. Biochem.Biophys.Res.Commun., 2005, 331, 520-526.
-
(2005)
Biochem.Biophys.Res.Commun
, vol.331
, pp. 520-526
-
-
OSHIMA, K.1
NAMPEI, A.2
MATSUDA, M.3
IWAKI, M.4
FUKUHARA, A.5
-
32
-
-
17344395628
-
Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter
-
MEISSNER U., OSTREICHER I., ALLABAUER I., RASCHER W., DOTSCH J. - Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter. Biochem.Biophys.Res.Commun., 2003, 303, 707-712.
-
(2003)
Biochem.Biophys.Res.Commun
, vol.303
, pp. 707-712
-
-
MEISSNER, U.1
OSTREICHER, I.2
ALLABAUER, I.3
RASCHER, W.4
DOTSCH, J.5
-
33
-
-
24344480012
-
Hypoxia and HIF-1a in chondrogenesis
-
SCHIPANI E. - Hypoxia and HIF-1a in chondrogenesis. Semin.Cell.Dev.Biol., 2005, 16, 539-546.
-
(2005)
Semin.Cell.Dev.Biol
, vol.16
, pp. 539-546
-
-
SCHIPANI, E.1
-
34
-
-
30044446067
-
RBP4, an unexpected adipokine
-
TAMORI Y., SAKANE H., KASUGA M. - RBP4, an unexpected adipokine. Nat.Med., 2006, 12, 30-31.
-
(2006)
Nat.Med
, vol.12
, pp. 30-31
-
-
TAMORI, Y.1
SAKANE, H.2
KASUGA, M.3
-
35
-
-
33144479356
-
Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue
-
SCHAFFLER A., NEUMEIER M., HERFARTH H., FURST A., SCHOLMERICH J. et al. - Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue. Biochem.Biophys.Acta. 2005, 1732, 96-102.
-
(2005)
Biochem.Biophys.Acta
, vol.1732
, pp. 96-102
-
-
SCHAFFLER, A.1
NEUMEIER, M.2
HERFARTH, H.3
FURST, A.4
SCHOLMERICH, J.5
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