Successful control of severe postoperative bleeding with recombinant factor VIIa in a case of refractory idiopathic thrombocytopenic purpura [3]

American Journal of Hematology

Volumn 82, Issue 3, 2007, Pages 246-247

  Aquilar, Carlos ^a   Lucía, José F ^b  

^a HOSPITAL SANTA BÁRBARA   (Spain)

^b HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOCAPROIC ACID; IMMUNOGLOBULIN; PREDNISOLONE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBOCYTE CONCENTRATE;

AGED; CASE REPORT; DRUG EFFICACY; ESOPHAGUS ACHALASIA; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; LETTER; MALE; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; THROMBOCYTE COUNT;

AGED; ANTIFIBRINOLYTIC AGENTS; FACTOR VIIA; HUMANS; MALE; POSTOPERATIVE HEMORRHAGE; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RECOMBINANT PROTEINS; TREATMENT OUTCOME;

EID: 33847642193     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.20728     Document Type: Letter

References (5)

1. Kristensen J, Killander A, Hippe E, et al. Clinical experience with recombinant factor VIIa in patients with thrombocytopenia. Haemostasia 1996;26(Suppl I):159-164.
2. Blatt J, Gold SH, Wiley JM, Monahan PE, Cooper HC, Harvey D. Off-label use of recombinant factor VIIa in patients following bone marrow transplantation. Bone Marrow Transplant 2001;28:405-407.
3. Vidarsson B, Omundarsson PT. Recombinant factor VIIa for bleeding in refractory thrombocytopenia. Thromb Haemost 2000;83:634-635.
4. Gerotziafas GT, Zervas C, Gavrielidis G, et al. Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage. Am J Hematol 2002;69:219-222.
5. Monroe DM, Hoffman M, Oliver JA, Roberts HR. Platelet activity of high-dose factor VIIa is independent of tissue factor. Br J Haematol 1997;99:542-547.