Comparison of resource utilisation, preference and handling of a pre-filled pen and vial/syringe in patients with type 2 diabetes mellitus

Journal of Clinical Research

Volumn 10, Issue 1-10, 2007, Pages 1-10

  Schwartz, Sherwyn ^a   Khutoryansky, Naum ^b   Braceras, Rogelio ^b  

^a Diabetes and Glandular Disease Clinic   (United States)

^b NOVO NORDISK INC   (United States)

Author keywords

Device preference; Diabetes; Dose accuracy and precision; FlexPen ; Insulin injection device; Insulin pen

Indexed keywords

INSULIN;

ACCURACY; ADULT; AGED; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; FEMALE; HEALTH CARE UTILIZATION; HUMAN; INJECTION; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NURSE; PATIENT EDUCATION; PATIENT SATISFACTION; PRE FILLED PEN; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SYRINGE; TRAINING;

EID: 33847634821     PISSN: 13695207     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Bell DS, Clements RS, Parentesis G et al. Dosage accuracy of self-mixed vs. premixed insulin. Archives of Internal Medicine 1991; 151: 2265-2269.
2. Kesson CM, Baile GR. Do diabetic patients inject accurate doses of insulin? Diabetes Care 1981; 4: 323.
3. Kreinhofer M, Aufseesser-Stein M, Assal JP. Insulin injections: mistakes and errors made by patients and/or health care providers. Diabetes Research and Clinical Practice 1988; 4(Suppl. 1): 35-40.
4. Puxty JA, Hunter DH, Burr WA. Accuracy of insulin injection in elderly patients. British Medical Journal (Clinical Research Ed) 1983; 287: 1762.
5. Coscelli C, Lostia S, Lunetta M et al. Safety, efficacy, acceptability of a pre-filled insulin pen in diabetic patients over 60 years old. Diabetes Research and Clinical Practice 1995; 28: 173-177
6. Hornquist JO, Wilky A, Anderson PO et al. Insulin pen treatment, quality of life and metabolic control: retrospective intra-group evaluations. Diabetes Research and Clinical Practice 1990; 10: 221-230.
7. Lteif AN, Schwenk WF. Accuracy of pen injectors versus insulin syringes in children with type 1 diabetes. Diabetes Care 1999; 22: 137-139.
8. Asakura T. Comparison of the dosing accuracy of two insulin injections devices. Journal of Clinical Research 2005; 8: 33-40.
9. Declaration of Helsinki. Recommendations guiding medical physicians in biomedical research involving human subjects. Journal of the American Medical Association 1997; 277: 925-926.
10. International Conference on Harmonisation. ICH Harmonised Tripartite Guideline. Good Clinical Practice. 1 May 1996. Available at: http://www.ich.org [accessed 16 October 2006].
11. Keith K, Nicholson D, Rogers D. Accuracy and precision of low-dose insulin administration using syringes, pen injectors, and a pump. Clinical Pediatrics 2004; 43: 69-74.
12. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. New England Journal of Medicine 1993; 329: 977-986.
13. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352: 837-853. [Erratum. Lancet 1999; 354: 602.]
14. Korytkowski M, Bell D, Jacobsen C et al. A multicenter, randomized, open-label, comparative, two-period crossover trial of preference, efficacy, and safety profiles of a prefilled, disposable pen and conventional vial/syringe for insulin injection in patients with type 1 or 2 diabetes mellitus. Clinical Therapeutics 2003; 25: 2836-2848.
15. Raskin P, Allen E, Hollander P et al; for the INITIATE Study Group. Initiating insulin therapy in type 2 diabetes: a comparison of biphasic and basal insulin analogs. Diabetes Care 2005; 28: 260-265.
16. Casella SJ, Mongilio MK, Plotnick LP et al. Accuracy and precision of low-dose insulin administration. Pediatrics 1993; 91: 1155-1157