α2-Adrenoreceptor mediated sympathoinhibition of heart rate during acute hypoxia is diminished in conscious prostacyclin synthase deficient mice

Pflugers Archiv European Journal of Physiology

Volumn 454, Issue 1, 2007, Pages 29-39

  Pearson, James T ^a,b   Shirai, Mikiyasu ^a,c   Yokoyama, Chieko ^a,d   Tsuchimochi, Hirotsugu ^a,e   Schwenke, Daryl O ^a   Shimouchi, Akito ^a   Kangawa, Kenji ^a   Tanabe, Tadashi ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b MONASH UNIVERSITY   (Australia)

^c HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e HIROSHIMA UNIVERSITY   (Japan)

Author keywords

2 Adrenergic receptor; Acute hypoxia; Prostaglandins; Respiratory control; Sympathetic nervous system; Transgenic mouse

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; IDAZOXAN; MECLOFENAMATE SODIUM; PROSTACYCLIN; PROSTACYCLIN SYNTHASE; PROSTAGLANDIN SYNTHASE; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOCHROME P450; ISOMERASE; MECLOFENAMIC ACID; PROSTAGLANDIN SYNTHASE INHIBITOR;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY PLETHYSMOGRAPHY; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; ENZYME INHIBITION; HEART MUSCLE ISCHEMIA; HEART RATE; HYPERTENSION; HYPOTENSION; HYPOXIA; INHIBITION KINETICS; INSPIRATORY CAPACITY; LUNG VENTILATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN DEFICIENCY; RECEPTOR POTENTIAL; RESPIROMETRY; STATISTICAL SIGNIFICANCE; SYMPATHETIC TONE; TACHYCARDIA; TELEMETRY; ACUTE DISEASE; ANIMAL; ANOXIA; BLOOD PRESSURE; BREATHING; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; METABOLISM; MOUSE MUTANT; NERVE CELL INHIBITION; PATHOPHYSIOLOGY;

ACUTE DISEASE; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANOXIA; BLOOD PRESSURE; CYCLOOXYGENASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; HEART RATE; HYPERTENSION; HYPOTENSION; IDAZOXAN; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MECLOFENAMIC ACID; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURAL INHIBITION; RECEPTORS, ADRENERGIC, ALPHA-2; RESPIRATION; SYMPATHETIC NERVOUS SYSTEM;

EID: 33847632411     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-006-0175-1     Document Type: Article

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