Delivery methods for peptide and protein toxins in insect control

Toxicon

Volumn 49, Issue 4, 2007, Pages 576-596

  Whetstone, Paul A ^a   Hammock, Bruce D ^b  

^a BAYER CORPORATION   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Arthropod; Delivery; Peptide; Pesticide; Toxin; Venom

Indexed keywords

BACILLUS THURINGIENSIS TOXIN; BACTERIAL DNA; CHLORPHENOTANE; FUNGAL DNA; INSECT HORMONE; INSECTICIDE; NEUROPEPTIDE; PEPTIDE; TOXIN; VIRUS DNA;

AEROSOL; ARTHROPOD; AUTOGRAPHA CALIFORNICA; BACILLUS THURINGIENSIS; BACULOVIRUS; BEAUVERIA; BIOLOGICAL PEST CONTROL; COST EFFECTIVENESS ANALYSIS; DNA MODIFICATION; ENZYME ACTIVITY; INSECT CONTROL; INSECT RESISTANCE; NONHUMAN; PHOTORHABDUS LUMINESCENS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW; XENORHABDUS NEMATOPHILA;

AGRICULTURE; ANIMALS; DRUG DELIVERY SYSTEMS; INSECT CONTROL; INSECTICIDES; PEPTIDES; PEST CONTROL, BIOLOGICAL; TOXINS, BIOLOGICAL;

ANIMALIA; ARTHROPODA; HEXAPODA;

EID: 33847614299     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.11.009     Document Type: Review

References (214)

1. Altstein M. Insect neuropeptide antagonists. Biopolymers 60 6 (2001) 460-473
2. Altstein M. Novel insect control agents based on neuropeptide antagonists: the PK/PBAN family as a case study. J. Mol. Neurosci. 22 1-2 (2004) 147-157
3. Altstein M., et al. Advances in the application of neuropeptides in insect control. Crop Prot. 19 8-10 (2000) 547-555
4. Aronson A.I., and Shai Y. Why Bacillus thuringiensis insecticidal toxins are so effective: unique features of their mode of action. FEMS Microbiol. Lett. 195 1 (2001) 1-8
5. Ashouri A., et al. Pathogenicity of the fungus, Verticillium lecanii, to the green peach aphid, Myzus persicae (Hom.: Aphididae). Commun. Agric. Appl. Biol. Sci. 69 3 (2004) 205-209
6. Attaran A., et al. Balancing risks on the backs of the poor. Nat. Med. 6 7 (2000) 729-731
7. Bai C., et al. Activity of insecticidal crystal proteins and strains of Bacillus thuringiensis against Spodoptera exempta (Walker). J. Invertebr. Pathol. 62 3 (1993) 211-215
8. Bajaj S., and Mohanty A. Recent advances in rice biotechnology-towards genetically superior transgenic rice. Plant Biotechnol. J. 3 3 (2005) 275-307
9. Beard C.B., et al. Bacterial symbiosis and paratransgenic control of vector-borne Chagas disease. Int. J. Parasitol. 31 5-6 (2001) 621-627
10. Ben-Aziz O., et al. PBAN selective antagonists: inhibition of PBAN induced cuticular melanization and sex pheromone biosynthesis in moths. J. Insect Physiol. 51 3 (2005) 305-314
11. Benitez T., et al. Biocontrol mechanisms of Trichoderma strains. Int. Microbiol. 7 4 (2004) 249-260
12. Bergvinson D., and Garcia-Lara S. Genetic approaches to reducing losses of stored grain to insects and diseases. Curr. Opin. Plant Biol. 7 4 (2004) 480-485
13. Bernal C.C., et al. Effect of rice lines transformed with Bacillus thuringiensis toxin genes on the brown planthopper and its predator Cyrtorhinus lividipennis. Entomol. Exp. Appl. 102 1 (2002) 21-28
14. Black B.C., et al. Commercialization of baculoviral insecticides. In: Miller L.K. (Ed). The Baculoviruses (1997), Plenum Press, New York 341-387
15. Blanford S., et al. Fungal pathogen reduces potential for malaria transmission. Science 308 5728 (2005) 1638-1641
16. Blissard G., et al. Family Baculoviridae. In: van Regenmortel M.H.V., Fauquet C.M., Bishop D.H.L., Carstens E.B., Estes M.K., Lemon S.M., McGeoch D.J., Maniloff J., Mayo M.A., Pringle C.R., and Wickner R.B. (Eds). Virus Taxonomy: Classification and Nomenclature of Viruses. Seventh Report of the International Committee for the Taxonomy of Viruses (2000), Academic Press, San Diego 195-202
17. Bonning B.C., and Hammock B.D. Development of recombinant baculoviruses for insect control. Annu. Rev. Entomol. 41 (1996) 191-210
18. Bonning B.C., et al. Further development of a recombinant baculovirus insecticide expressing the enzyme juvenile hormone esterase from Heliothis virescens. Insect Biochem. Mol. Biol. 22 5 (1992) 453-458
19. Bonning B.C., et al. Genetic Enhancement of Baculovirus Insecticides (2002), Kluwer Academic/Plenum Publishers, New York
20. Borovsky D. Biosynthesis and control of mosquito gut proteases. IUBMB Life 55 8 (2003) 435-441
21. Borovsky D. Trypsin-modulating oostatic factor: a potential new larvicide for mosquito control. J. Exp. Biol. 206 Pt 21 (2003) 3869-3875
22. Borovsky D., and Mahmood F. Feeding the mosquito Aedes aegypti with TMOF and its analogs; effect on trypsin biosynthesis and egg development. Regul. Pept. 57 3 (1995) 273-281
23. Borovsky D., et al. Mosquito oostatic factor: a novel decapeptide modulating trypsin-like enzyme biosynthesis in the midgut. Faseb J. 4 12 (1990) 3015-3020
24. Borovsky D., et al. Mass spectrometry and characterization of Aedes aegypti trypsin modulating oostatic factor (TMOF) and its analogs. Insect Biochem. Mol. Biol. 23 6 (1993) 703-712
25. Bothner B., et al. Maturation of a tetravirus capsid alters the dynamic properties and creates a metastable complex. Virology 334 1 (2005) 17-27
26. Boulter D. Insect pest control by copying nature using genetically engineered crops. Phytochemistry 34 6 (1993) 1453-1466
27. Brogdon W.G., and McAllister J.C. Insecticide resistance and vector control. Emerg. Infect. Dis. 4 4 (1998) 605-613
28. Brunelle F., et al. A hybrid, broad-spectrum inhibitor of Colorado potato beetle aspartate and cysteine digestive proteinases. Arch. Insect Biochem. Physiol. 60 1 (2005) 20-31
29. Burden J.P., et al. Infectivity, speed of kill, and productivity of a baculovirus expressing the itch mite toxin txp-1 in second and fourth instar larvae of Trichoplusia ni. J. Invertebr. Pathol. 75 3 (2000) 226-236
30. Burgess E.P., et al. Avidin expressed in transgenic tobacco leaves confers resistance to two noctuid pests, Helicoverpa armigera and Spodoptera litura. Transgenic Res. 11 2 (2002) 185-198
31. Bylemans D., et al. Sequencing and characterization of trypsin modulating oostatic factor (TMOF) from the ovaries of the grey fleshfly, Neobellieria (Sarcophaga) bullata. Regul. Pept. 50 1 (1994) 61-72
32. Caltagirone L.E. Landmark Examples in Classical Biological-Control. Annu. Rev. Entomol. 26 (1981) 213-232
33. Cao J., et al. Transgenic tobacco plants carrying a baculovirus enhancin gene slow the development and increase the mortality of Trichoplusia ni larvae. Plant Cell Rep. 21 3 (2002) 244-250
34. Carbonell L.F., et al. Synthesis of a gene coding for an insect specific scorpion neurotoxin and attempts to express it using baculovirus vectors. Gene 73 (1988) 409-418
35. Casida J.E., and Quistad G.B. Golden age of insecticide research: past, present, or future?. Annu. Rev. Entomol. 43 (1998) 1-16
36. Cestèle S., and Catterall W.A. Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. Biochimie 82 9-10 (2000) 883-892
37. Chang J.H., et al. An improved baculovirus insecticide producing occlusion bodies that contain Bacillus thuringiensis insect toxin. J. Invertebr. Pathol. 84 1 (2003) 30-37
38. Chao Y.C., et al. Pest control by fluorescence. Nature 380 6573 (1996) 396-397
39. Chattopadhyay A., et al. Bacterial insecticidal toxins. Crit. Rev. Microbiol. 30 1 (2004) 33-54
40. Chejanovsky N., et al. Functional expression of an alpha anti-insect scorpion neurotoxin in insect cells and lepidopterous larvae. FEBS Lett. 376 (1995) 181-184
41. Chen K.C., et al. A novel defensin encoded by a mungbean cDNA exhibits insecticidal activity against bruchid. J. Agric. Food Chem. 50 25 (2002) 7258-7263
42. Chen X.W., et al. Genetic engineering of Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus as an improved pesticide. J. Invertebr. Pathol. 76 2 (2000) 140-146
43. Cheng Z.Y., and Xue Q.Z. The structure and regulation of plant proteinase inhibitor genes and their strategy in pest control. Yi Chuan Xue Bao 30 8 (2003) 790-796
44. Cohen E. Chitin biochemistry: synthesis and inhibition. Annu. Rev. Entomol. 32 (1987) 71-93
45. Copping L.G., and Menn J.J. Biopesticides: a review of their action, applications and efficacy. Pest Management Science 56 8 (2000) 651-676
46. Cory J.S., et al. Field trial of a genetically improved baculovirus insecticide. Nature (London) 370 (1994) 138-140
47. Corzo G., and Escoubas P. Pharmacologically active spider peptide toxins. Cell Mol. Life Sci. 60 11 (2003) 2409-2426
48. Dahlman D.L., et al. A teratocyte gene from a parasitic wasp that is associated with inhibition of insect growth and development inhibits host protein synthesis. Insect Mol. Biol. 12 5 (2003) 527-534
49. Darbon H., et al. Covalent structure of the insect toxin of the North African scorpion Androctonus australis Hector. Int. J. Pep. Prot. Res. 20 4 (1982) 320-330
50. Dinan L. Phytoecdysteroids: biological aspects. Phytochemistry 57 3 (2001) 325-339
51. Downing K.J., and Thomson J.A. Introduction of the Serratia marcescens chiA gene into an endophytic Pseudomonas fluorescens for the biocontrol of phytopathogenic fungi. Can. J. Microbiol. 46 4 (2000) 363-369
52. Downing K.J., et al. Biocontrol of the sugarcane borer Eldana saccharina by expression of the Bacillus thuringiensis cry1Ac7 and Serratia marcescens chiA genes in sugarcane-associated bacteria. Appl. Environ. Microbiol. 66 7 (2000) 2804-2810
53. Elazar M., et al. Targeting of an expressed neurotoxin by its recombinant baculovirus. J. Exp. Biol. 204 Pt 15 (2001) 2637-2645
54. Eldridge R., et al. Expression of an eclosion hormone gene in insect cells using baculovirus vectors. Insect Biochem. 21 (1991) 341-351
55. Eldridge R., et al. Insecticidal properties of genetically engineered baculoviruses expressing an insect juvenile hormone esterase gene. Appl. Environ. Microbiol. 58 5 (1992) 1583-1591
56. Eldridge R., et al. Efficacy of a baculovirus pesticide expressing an eclosion hormone gene. Biol. Control 2 (1992) 104-110
57. Elzen G.W., and Hardee D.D. United States Department of Agriculture-Agricultural Research Service research on managing insect resistance to insecticides. Pest Manag. Sci. 59 6-7 (2003) 770-776
58. 2+ release channel/ryanodine receptors. FEBS Lett. 469 2-3 (2000) 179-185
59. Federici B.A. Insecticidal bacteria: an overwhelming success for invertebrate pathology. J. Invertebr. Pathol. 89 1 (2005) 30-38
60. Ferre J., and Van Rie J. Biochemistry and genetics of insect resistance to Bacillus thuringiensis. Annu. Rev. Entomol. 47 (2002) 501-533
61. Feyereisen R. Molecular biology of insecticide resistance. Toxicol. Lett. 82-83 (1995) 83-90
62. ffrench-Constant R.H., and Bowen D.J. Novel insecticidal toxins from nematode-symbiotic bacteria. Cell Mol. Life Sci. 57 5 (2000) 828-833
63. Froy O., et al. Scorpion neurotoxins: structure/function relationships and application in agriculture. Pest Manage. Sci. 56 (2000) 472-474
64. Fuxa J.R. Release and transport of entomopathogenic microorganisms. In: Levin M., and Strauss H. (Eds). Risk Assessment in Genetic Engineering (1991), McGraw-Hill, New York 83-113
65. Gade G. Regulation of intermediary metabolism and water balance of insects by neuropeptides. Annu. Rev. Entomol. 49 (2004) 93-113
66. Gade G., and Goldsworthy G.J. Insect peptide hormones: a selective review of their physiology and potential application for pest control. Pest Manage. Sci. 59 10 (2003) 1063-1075
67. Gade G., and Hoffmann K.H. Neuropeptides regulating development and reproduction in insects. Physiol. Entomol. 30 2 (2005) 103-121
68. Gayle A., and Ringdahl E. Tick-borne diseases. Am. Fam. Physician 64 3 (2001) 461-466
69. Gershburg E., et al. Baculovirus-mediated expression of a scorpion depressant toxin improves the insecticidal efficacy achieved with excitatory toxins. FEBS Lett. 422 2 (1998) 132-136
70. Gill S.S., et al. The mode of action of Bacillus thuringiensis endotoxins. Annu. Rev. Entomol. 37 (1992) 615-636
71. Girardie J., et al. Expression of neuroparsin cDNA in insect cells using baculovirus vectors. Arch. Insect Biochem. Physiol. 46 (2001) 26-35
72. Gopalakrishnan B., et al. Properties of an insect chitinase produced in a baculovirus gene expression system. Abstracts of Papers of the American Chemical Society 205 (1993) 79-Agro
73. Gopalakrishnan K., et al. Baculovirus-mediated expression of a Manduca sexta chitenase gene: Properties of the recombinant protein. Insect Biochem. Mol. Biol. 25 (1995) 255-265
74. Gordon D., et al. Functional anatomy of scorpion toxins affecting sodium channels. J. Toxicol.-Toxin Rev. 17 2 (1998) 131-159
75. Gordon K.H., et al. The larger genomic RNA of Helicoverpa armigera stunt tetravirus encodes the viral RNA polymerase and has a novel 3′-terminal tRNA-like structure. Virology 208 1 (1995) 84-98
76. Gould W.P., and Jeanne R.L. Polistes wasps (Hymenoptera: Vespidae) as control agents for lepidopterous cabbage pests. Environ. Entomol. 13 (1984) 150-156
77. Granados R.R., et al. Enhancement of Bacillus thuringiensis toxicity to lepidopterous species with the enhancin from Trichoplusia ni granulovirus. Biol. Control 20 2 (2001) 153-159
78. Gratz N.G. Emerging and resurging vector-borne diseases. Annu. Rev. Entomol. 44 (1999) 51-75
79. Gubler D.J. Dengue and dengue hemorrhagic fever. Clin. Microbiol. Rev. 11 3 (1998) 480-496
80. Gubler D.J. The global pandemic of dengue/dengue haemorrhagic fever: current status and prospects for the future. Ann. Acad. Med. Singapore 27 2 (1998) 227-234
81. Gubler D.J. Resurgent vector-borne diseases as a global health problem. Emerg. Infect. Dis. 4 3 (1998) 442-450
82. Gunning R.V., et al. New resistance mechanism in Helicoverpa armigera threatens transgenic crops expressing Bacillus thuringiensis Cry1Ac toxin. Appl. Environ. Microbiol. 71 5 (2005) 2558-2563
83. Hammock B.D., et al. Expression and effects of the juvenile hormone esterase in a baculovirus vector. Nature 344 6265 (1990) 458-461
84. Hammock B.D., et al. Cloning, expression and biological activity of the juvenile hormone esterase from Heliothis virescens. In: Hagedorn H., Hildebrand J., Kidwell M., and Law J. (Eds). Molecular Insect Science (1990), Plenum Press, New York 49-56
85. Hammock B.D., et al. Development of recombinant viral insecticides by expression of an insect-specific toxin and insect-specific enzyme in nuclear polyhedrosis viruses. Arch. Insect Biochem. Physiol. 22 2-4 (1993) 315-344
86. Hanzlik T.N., et al. Sequence of RNA2 of the Helicoverpa armigera stunt virus (Tetraviridae) and bacterial expression of its genes. J. Gen. Virol. 76 Pt 4 (1995) 799-811
87. Harrison R.L., and Bonning B.C. The nucleopolyhedroviruses of Rachiplusia ou and Anagrapha falcifera are isolates of the same virus. J. Gen. Virol. 80 (1999) 2793-2798
88. Harrison R.L., and Bonning B.C. Use of scorpion neurotoxins to improve the insecticidal activity of Rachiplusia ou multicapsid nucleopolyhedrovirus. Biol. Control 17 2 (2000) 191-201
89. Harrison R.L., and Bonning B.C. Use of proteases to improve the insecticidal activity of baculoviruses. Biol. Control 20 3 (2001) 199-209
90. Haselton A.T., et al. Peptidergic innervation of the crop and the effects of an ingested nonpeptidal agonist on longevity in female Musca domestica (Diptera: Muscidae). J. Med. Entomol. 41 4 (2004) 684-690
91. Hastings C. Penthaleus major. An occasional little-known pest. Phytoma 465 (1994) 43-44
92. Hayakawa T., et al. Enhancement of baculovirus infection in Spodoptera exigua (Lepidoptera: Noctuidae) larvae with Autographa californica nucleopolyhedrovirus or Nicotiana tabacum engineered with a granulovirus enhancin gene. Appl. Entomol. Zool. 35 1 (2000) 163-170
93. High S.M., et al. Achieving successful deployment of Bt rice. Trends Plant Sci. 9 6 (2004) 286-292
94. Holman G.M., et al. Insect neuropeptides. Annu. Rev. Entomol. 35 (1990) 201-217
95. Hom L.G., and Volkman L.E. Autographa californica M nucleopolyhedrovirus chiA is required for processing of V-CATH. Virology 277 1 (2000) 178-183
96. Hoover K., et al. Reduction in damage to cotton plants by a recombinant baculovirus that knocks moribund larvae of Heliothis virescens off the plant. Biol. Control 5 3 (1995) 419-426
97. Hughes P.R., et al. Enhanced bioactivity of recombinant baculoviruses expressing insect-specific spider toxins in lepidopteran crop pests. J. Invertebr. Pathol. 69 2 (1997) 112-118
98. Hunter-Fujita F.R., et al. Insect Viruses and Pest Management (1998), Wiley, Chichester
99. Imai K., et al. Isolation and structure of diapause hormone of the silkworm, Bombyx mori. Proc. Jpn. Acade. Ser. Phys. Biol. Sci. 67 6 (1991) 98-101
100. Imai N., et al. Insecticidal effects of a recombinant baculovirus expressing scorpion toxin LqhIT2. J. Seric. Sci. Jpn. 69 (2000) 197-205
101. Inceoglu A.B., et al. Recombinant baculoviruses for insect control. Pest Manage. Sci. 57 10 (2001) 981-987
102. Inceoglu B., et al. Isolation and characterization of a novel type of neurotoxic peptide from the venom of the South African scorpion Parabuthus transvaalicus (Buthidae). Eur. J. Biochem. 268 20 (2001) 5407-5413
103. Inceoglu B., et al. One scorpion, two venoms: Prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proc. Nat. Acad. Sci. US A 100 3 (2003) 922-927
104. Inglis G.D., and Lawrence A.M. Effects of Serratia marcescens on the F1 generation of laboratory-reared Heliothis virescens (Lepidoptera: Noctuidae). J. Econ. Entomol. 94 2 (2001) 362-366
105. Jackson T.A., et al. Oryctes virus-time for a new look at a useful biocontrol agent. J. Invertebr. Pathol. 89 1 (2005) 91-94
106. Jennings C., et al. Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis. Proc. Natl. Acad. Sci. USA 98 19 (2001) 10614-10619
107. Kamita S.G., et al. Genetically Modified Baculoviruses for Pest Insect Control. In: Gilbert L.I., Iatrou K., and Gill S.S. (Eds). Comprehensive Molecular Insect Science vol. 6 (2005), Elsevier, Amsterdam, Boston 271-322
108. Keeley L.L., and Hayes T.K. Speculations on biotechnology applications for insect neuroendocrine research. Insect Biochem. 17 5 (1987) 639-651
109. Kerwin J.L., and Washino R.K. Ground and aerial application of the asexual stage of Lagenidium giganteum for control of mosquitoes associated with rice culture in the Central Valley of California. J. Am. Mosq. Control Assoc. 3 1 (1987) 59-64
110. Kerwin J.L., et al. Pilot scale production and application in wildlife ponds of Lagenidium giganteum (Oomycetes: Lagenidiales). J. Am. Mosq. Control Assoc. 10 3 (1994) 451-455
111. Kim J.J., et al. Impact of the entomopathogenic fungus Verticillium lecanii on development of an aphid parasitoid, Aphidius colemani. J. Invertebr. Pathol. 88 3 (2005) 254-256
112. Kondrashin A.V., and Rooney W. Overview: epidemiology of malaria and its control in countries of the WHO South-East Asia region. Southeast Asian J. Trop. Med. Public Health 23 Suppl. 4 (1992) 13-22
113. Kopeyan C., et al. Primary structure of scorpion anti-insect toxins isolated from the venom of Leiurus quinquestriatus quinquestriatus. FEBS Lett. 261 (1990) 424-426
114. Kramer K.J., and Muthukrishnan S. Insect chitinases: molecular biology and potential use as biopesticides. Insect Biochem. Mol. Biol. 27 11 (1997) 887-900
115. Krogstad D.J. Malaria as a reemerging disease. Epidemiol. Rev. 18 1 (1996) 77-89
116. Lacey L.A., et al. Insect pathogens as biological control agents: Do they have a future?. Biol. Control 21 3 (2001) 230-248
117. Lange A.B., et al. A nonpeptide agonist of the invertebrate receptor for SchistoFLRFamide (PDVDHVFLRFamide), a member of a subfamily of insect FMRFamide-related peptides. Proc. Natl. Acad. Sci. USA 92 20 (1995) 9250-9253
118. Lay F.T., and Anderson M.A. Defensins-components of the innate immune system in plants. Curr. Protein Pept. Sci. 6 1 (2005) 85-101
119. Lepore L.S., et al. Enhancin, the granulosis virus protein that facilitates nucleopolyhedrovirus (NPV) infections, is a metalloprotease. J. Invertebr. Pathol. 68 2 (1996) 131-140
120. Li Q.J., et al. Characterization of Mamestra configurata nucleopolyhedrovirus enhancin and its functional analysis via expression in an Autographa californica M nucleopolyhedrovirus recombinant. J. Gen. Virol. 84 (2003) 123-132
121. Loret E.P., and Hammock B.D. Structure and neurotoxicity of scorpion venom. In: Brownell P.H., and Polis G. (Eds). Scorpion Biology and Research (1993), Oxford University Press, Oxford, UK 204-233
122. Lu A., et al. Signal sequence and promoter effects on the efficacy of toxin-expressing baculoviruses as biopesticides. Biol. Control 7 3 (1996) 320-332
123. Ma P.W.K., et al. Baculovirus expression of an insect gene that encodes multiple neuropeptides. Insect Biochem. Mol. Biol. 28 4 (1998) 239-249
124. Macdonald P., and Yarrow S. Regulation of Bt crops in Canada. J. Invertebr. Pathol. 83 2 (2003) 93-99
125. Maeda S. Increased insecticidal effect by a recombinant baculovirus carrying a synthetic diuretic hormone gene. Biochem. Biophys. Res. Comm. 165 (1989) 1177-1183
126. Maeda S., et al. Insecticidal effects of an insect-specific neurotoxin expressed by a recombinant baculovirus. Virology 184 (1991) 777-780
127. Maqbool S.B., et al. Expression of multiple insecticidal genes confers broad resistance against a range of different rice pests. Mol. Breed. 7 1 (2001) 85-93
128. Martens J.W.M., et al. Insecticidal activity of a bacterial crystal protein expressed by a recombinant baculovirus in insect cells. Appl. Environ. Microbiol. 56 (1990) 2764-2770
129. Martens J.W.M., et al. Characterization of baculovirus insecticides expressing tailored Bacillus thuringiensis Cry1a(B) crystal proteins. J. Invertebr. Pathol. 66 3 (1995) 249-257
130. McCutchen B.F., and Hammock B.D. Recombinant baculovirus expressing an insect-selective neurotoxin: Characterization, strategies for improvement and risk assessment. In: Hedin P.A., Menn J.J., and Hollingworth R.M. (Eds). Natural and Engineered Pest Management Agents (1994), American Chemical Society, Washington, DC 348-367
131. McCutchen B.F., et al. Development of a recombinant baculovirus expressing an insect-selective neurotoxin: potential for pest control. Bio/Technol. 9 (1991) 848-852
132. Mehlo L., et al. An alternative strategy for sustainable pest resistance in genetically enhanced crops. Proc. Nat. Acad. Sci. US A 102 22 (2005) 7812-7816
133. Menn J.J., and Borkovec A.B. Insect neuropeptides-potential new insect control agents. J. Agric. Food Chem. 37 1 (1989) 271-278
134. Merrington C.L., et al. Baculovirus expression systems. In: Higgins S.J., and Hames B.D. (Eds). Protein Expression: A Practical Approach (1999), Oxford University Press, Oxford
135. Merryweather A.T., et al. Construction of genetically engineered baculovirus insecticides containing the Bacillus thuringiensis subsp. kurstaki HD-73 delta endotoxin. J. Gen. Virol. 71 (1990) 1535-1544
136. Miller L.K. Genetically engineered insect virus pesticides: present and future. J. Invertebr. Pathol. 65 (1995) 211-216
137. Moerman L., et al. Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur. J. Biochem. 269 19 (2002) 4799-4810
138. 2+ signaling in HL-60 cells. Biochem. Biophys. Res. Commun. 311 1 (2003) 90-97
139. Moscardi F. Assessment of the application of baculoviruses for control of Lepidoptera. Annu. Rev. Entomol. 44 (1999) 257-289
140. Moskowitz H., et al. A depressant insect-selective toxin analog from the venom of the scorpion Leiurus quinquestriatus hebraeus, purification and structure/function characterization. Eur. J. Biochem. 254 (1998) 44-49
141. Nachman R.J., et al. Active fragments and analogs of the insect neuropeptide leucopyrokinin: structure-function studies. Biochem. Biophys. Res. Commun. 137 3 (1986) 936-942
142. Nachman R.J., et al. Silkworm diapause induction activity of myotropic pyrokinin (FXPRLamide) insect neuropeptides. Peptides 14 5 (1993) 1043-1048
143. Nachman R.J., et al. A nonpeptidal peptidomimetic agonist of the insect FLRFamide myosuppressin family. Peptides 17 2 (1996) 313-320
144. Nauen R., et al. TMOF-like factor controls the biosynthesis of serine proteases in the larval gut of Heliothis virescens. Arch. Insect Biochem. Physiol. 47 4 (2001) 169-180
145. Neale M. The regulation of natural products as crop-protection agents. Pest Manage. Sci. 56 8 (2000) 677-680
146. Nicholson G.M. Spider venom peptides. In: Kastin A.J. (Ed). The Handbook of Biologically Active Peptides (2006), Elsevier, San Diego, CA 389-399
147. O'Callaghan M., et al. Effects of plants genetically modified for insect resistance on nontarget organisms. Annu. Rev. Entomol. 50 1 (2005) 271-292
148. Oerke E.-C. Estimated crop looses due to pathogens, animal pests and weeds. In: Oerke E.-C., Dehne H.-W., Schonbeck F., and Weber A. (Eds). Crop Production and Crop Production-Estimated Losses in Major Food and Cash Crops (1994), Elsevier, Amsterdam 72-78
149. Olivera B.M. Conus venom peptides: reflections from the biology of clades and species. Annu. Rev. Ecol. System. 33 (2002) 25-47
150. O'Reilly D.R. Auxilary genes of baculoviruses. In: Miller L.K. (Ed). The Baculoviruses (1997), Plenum Press, New York 267-300
151. O'Reilly D.R., et al. Baculovirus Expression Vectors: A Laboratory Manual (1992), W. H. Freeman and Co, New York
152. O'Reilly D.R., et al. Overexpression of Bombyx mori prothoracicotropic hormone using baculovirus vectors. Insect Biochem. Mol. Biol. 25 (1995) 475-485
153. Parola P., and Raoult D. Ticks and tickborne bacterial diseases in humans: an emerging infectious threat. Clin. Infect Dis. 32 6 (2001) 897-928
154. Peng C.Y.S., et al. Virulence and site of infection of the fungus, Hirsutella thompsonii, to the honey bee ectoparasitic mite, Varroa destructor. J. Invertebr. Pathol. 81 (2002) 185-195
155. Petersen L.R., and Roehrig J.T. West Nile virus: a reemerging global pathogen. Emerg. Infect. Dis. 7 4 (2001) 611-614
156. Popham H.J.R., et al. Both Lymantria dispar nucleopolyhedrovirus enhancin genes contribute to viral potency. J. Virol. 75 18 (2001) 8639-8648
157. +-channels. Eur. J. Biochem. 264 2 (1999) 287-300
158. Prikhod'ko G.G., et al. Properties of three baculoviruses expressing genes that encode insect-selective toxins: mu-Aga-IV, As II, and SH I. Biol. Control 7 2 (1996) 236-244
159. Pringle F.M., et al. Providence virus: a new member of the Tetraviridae that infects cultured insect cells. Virology 306 2 (2003) 359-370
160. Punja Z.K., and Utkhede R.S. Using fungi and yeasts to manage vegetable crop diseases. Trends Biotechnol. 21 9 (2003) 400-407
161. Quistad G.B., and Skinner W.S. Isolation and sequencing of insecticidal peptides from the primitive hunting spider, Plectreurys tristis (Simon). J. Biol. Chem. 269 15 (1994) 11098-11101
162. Ramesh S., et al. Production of transgenic indica rice resistant to yellow stem borer and sap-sucking insects, using super-binary vectors of Agrobacterium tumefaciens. Plant Sci. 166 4 (2004) 1077-1085
163. Randolph S.E. The shifting landscape of tick-borne zoonoses: tick-borne encephalitis and Lyme borreliosis in Europe. Philos. Trans. R Soc. Lond. B Biol. Sci. 356 1411 (2001) 1045-1056
164. Regev A., et al. Further enhancement of baculovirus insecticidal efficacy with scorpion toxins that interact cooperatively. FEBS Lett. 537 1-3 (2003) 106-110
165. Ribeiro B.M., and Crook N.E. Expression of full-length and truncated forms of crystal protein genes from Bacillus thuringiensis subsp. kurstaki in a baculovirus and pathogenicity of the recombinant viruses. J. Invertebr. Pathol. 62 2 (1993) 121-130
166. Ribeiro B.M., and Crook N.E. Construction of occluded recombinant baculoviruses containing the full-length cry1Ab and cry1Ac genes from Bacillus thuringiensis. Brazilian J. Med. Biol. Res. 31 6 (1998) 763-769
167. Richardson C.D. Baculovirus Expression Protocols (1995), Humana Press, Totowa
168. Richer S., et al. Innervation of dromyosuppressin (DMS) immunoreactive processes and effect of DMS and benzethonium chloride on the Phormia regina (Meigen) crop. J. Comp. Neurol. 421 1 (2000) 136-142
169. Rodhain F. Recent data on the epidemiology of Japanese encephalitis. Bull. Acad. Natl. Med. 180 6 (1996) 1325-1337 discussion 1338-1340
170. Schnepf E., et al. Bacillus thuringiensis and its pesticidal crystal proteins. Microbiol. Mol. Biol. Rev. 62 3 (1998) 775
171. Scholte E.J., et al. An entomopathogenic fungus for control of adult African malaria mosquitoes. Science 308 5728 (2005) 1641-1642
172. Schoofs L., et al. Isolation, primary structure, and synthesis of locustapyrokinin: a myotropic peptide of Locusta migratoria. Gen. Comp. Endocrinol. 81 1 (1991) 97-104
173. Seo J.H., et al. Baculoviral polyhedrin-Bacillus thuringiensis toxin fusion protein: a protein-based bio-insecticide expressed in E. coli. Biotechnol. Bioeng. 92 2 (2005) 166-172
174. Sharma H.C., et al. Genetic transformation of crops for insect resistance: Potential and limitations. Crit. Rev. Plant Sci. 23 1 (2004) 47-72
175. Slack J.M., et al. Characterization of V-Cath, a cathepsin L-like proteinase expressed by the baculovirus Autographa californica multiple nuclear polyhedrosis virus. J. Gen. Virol. 76 (1995) 1091-1098
176. Stewart L.M., et al. Construction of an improved baculovirus insecticide containing an insect-specific toxin gene. Nature 352 (1991) 85-88
177. Summers, M.D., Smith, G.E., 1987. A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures, Texas Agricultural Experiment Station Bulletin No 1555.
178. Sun X., et al. Biological activity and field efficacy of a genetically modified Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus expressing an insect-selective toxin from a chimeric promoter. Biol. Control 29 (2004) 124-137
179. Sun X.L., et al. Bollworm responses to release of genetically modified Helicoverpa armigera nucleopolyhedroviruses in cotton. J. Invertebr. Pathol. 81 2 (2002) 63-69
180. Taborsky V. Small-scale Processing of Microbial Pesticides (1992), Food and Agriculture Organization of the United Nations
181. Tal J., and Attathom T. Insecticidal potential of the insect parvovirus GmDNV. Arch. Insect Biochem. Physiol. 22 3-4 (1993) 345-356
182. Tanada Y. Synergism between two viruses of the armyworm Pseudaletia unipuncta (Haworth) (Lepidoptera, Noctuidae). J. Insect Pathol. 6 (1959) 378-380
183. Tanada Y., and Kaya H.K. Insect Pathology (1993), Academic Press, Inc, San Diego
184. Taniai K., et al. Expression efficiency of a scorpion neurotoxin, AaHIT, using baculovirus in insect cells. Appl. Entomol. Zool. 37 2 (2002) 225-232
185. Tedford H.W., et al. Australian funnel-web spiders: master insecticide chemists. Toxicon 43 5 (2004) 601-618
186. Tomalski M.D., and Miller L.K. Insect paralysis by baculovirus-mediated expression of a mite neurotoxin gene. Nature 352 6330 (1991) 82-85
187. Tomalski M.D., and Miller L.D. Expression of a paralytic neurotoxin gene to improve insect baculoviruses as biopesticides. Bio/Technol. 10 (1992) 545-549
188. Tomalski M.D., et al. Preliminary characterization of toxins from the straw itch mite, Pyemotes tritici, which induce paralysis in the larvae of a moth. Toxicon 26 2 (1988) 127-132
189. Tomalski M.D., et al. Purification and characterization of insect toxins derived from the mite, Pyemotes tritici. Toxicon 27 10 (1989) 1151-1167
190. Tomalski M.D., et al. Identification and characterization of Tox21a-a mite cDNA encoding a paralytic neurotoxin related to Txp-I. Toxicon 31 3 (1993) 319-326
191. Tortiglione C., et al. The expression in tobacco plants of Aedes aegypti Trypsin Modulating Oostatic Factor (Aea-TMOF) alters growth and development of the tobacco budworm, Heliothis virescens. Mol. Breed. 9 3 (2002) 159-169
192. Treacy M.F., et al. Comparative insecticidal properties of two nucleopolyhedrovirus vectors encoding a similar toxin gene chimer. J. Econ. Entomol. 93 4 (2000) 1096-1104
193. Umina P.A., et al. Biology, ecology and control of the Penthaleus species complex (Acari: Penthaleidae). Exp. Appl. Acarol. 34 3-4 (2004) 211-237
194. Vail P.V., et al. Development of the multi-nucleocapsid nucleopolyhedroviruses (MNPVs) infectious to loopers (Lepidoptera: Noctuidae: Plusiinae) as microbial control agents. Integr. Pest Manage. Rev. 4 (1999) 231-257
195. Vakharia V.N., et al. Synthetic pheromone biosynthesis activating neuropeptide gene expressed in a baculovirus expression system. Insect Biochem. Mol. Biol. 25 (1995) 583-589
196. Volynski K.E., et al. Functional expression of alpha-latrotoxin in baculovirus system. FEBS Lett. 442 1 (1999) 25-28
197. Walker D.H. Principles of the malicious use of infectious agents to create terror: reasons for concern for organisms of the genus Rickettsia. Ann. N Y Acad. Sci. 990 (2003) 739-742
198. Wang X., et al. Structure-function studies of omega-atracotoxin, a potent antagonist of insect voltage-gated calcium channels. Eur. J. Biochem. 264 2 (1999) 488-494
199. Warburg A. Entomopathogens of phlebotomine sand flies: laboratory experiments and natural infections. J. Invertebr. Pathol. 58 2 (1991) 189-202
200. Whalon M.E., and Wingerd B.A. Bt: Mode of action and use. Arch. Insect Biochem. Physiol. 54 4 (2003) 200-211
201. Woo S.D., et al. The morphology of the polyhedra of a host range-expanded recombinant baculovirus and its parents. Arch. Virol. 143 6 (1998) 1209-1214
202. Wood H.A. Genetically enhanced baculovirus insecticides. In: Gunasekaran M., and Weber D.J. (Eds). Molecular Biology of the Biological Control of Pests and Diseases of Plants (1995), CRC Press, Boca Raton
203. Wudayagiri R., et al. Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus. BMC Biochem. 2 1 (2001) 16-23
204. Yamamoto D., et al. Leucomyosuppressin, a novel insect neuropeptide, inhibits evoked transmitter release at the mealworm neuromuscular junction. Neurosci. Lett. 95 1-3 (1988) 137-142
205. Yamamoto T., and Tanada Y. Phospholipid, an enhancing component in synergistic factor of a granulosis virus of armyworm, Pseudaletia unipuncta. J. Invertebr. Pathol. 31 1 (1978) 48-56
206. Yamamoto T., and Tanada Y. Protein components of 2 strains of granulosis virus of armyworm, Pseudaletia unipuncta (Lepidoptera, Noctuidae). J. Invertebr. Pathol. 32 2 (1978) 158-170
207. Yi F., et al. Isolation and identification of a new tetravirus from Dendrolimus punctatus larvae collected from Yunnan Province, China. J. Gen. Virol. 86 Pt 3 (2005) 789-796
208. Yue C., et al. Improved production of insecticidal proteins in Bacillus thuringiensis strains carrying an additional cry1C gene in its chromosome. Biotechnol. Bioeng. 92 1 (2005) 1-7
209. Zlotkin E. Venom neurotoxins-models for selective insecticides. Phytoparasitica 19 3 (1991) 177-182
210. Zlotkin E., et al. Venoms of Buthinae. In: Bettini S. (Ed). Arthropod Venoms (1978), Springer, New York 317-369
211. Zlotkin E., et al. An excitatory and a depressant insect toxin from scorpion venom both affect sodium conductance and possess a common binding site. Arch. Biochem. Biophys. 240 2 (1985) 877-887
212. Zlotkin E., et al. Depressant insect selective neurotoxins from scorpion venom-chemistry, action, and gene cloning. Arch. Insect Biochem. Physiol. 22 1-2 (1993) 55-73
213. Zlotkin E., et al. Insect sodium channel as the target for insect-selective neurotoxins from scorpion venom. ACS Symp. Ser. 591 (1995) 56-85
214. Zlotkin E., et al. AaIT: From neurotoxin to insecticide. Biochimie 82 9-10 (2000) 869-881