Retinal charge sensitivity and spatial discrimination obtainable by subretinal implants: Key lessons learned from isolated chicken retina

Journal of Neural Engineering

Volumn 4, Issue 1, 2007, Pages

  Stett, Alfred ^a   Mai, Andreas ^a   Herrmann, Thoralf ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRODES; IMPLANTS (SURGICAL); OPTICAL TRANSFER FUNCTION; THRESHOLD VOLTAGE; VISION;

CATHODAL IMPULSES; ELECTRICAL POINT SPREAD FUNCTION (EPSF); ELECTRICAL STIMULATION; RETINA;

BIOLOGICAL ORGANS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHICKEN; ELECTRIC POTENTIAL; ELECTRODE; ELECTROSTIMULATION; EYE; IMPLANT; ISOLATED RETINA; NEEDLE ELECTRODE; NONHUMAN; PLANAR DISC ELECTRODE; PRIORITY JOURNAL; RETINA; SPATIAL DISCRIMINATION; SPIKE; SUBRETINAL IMPLANT; VISUAL ACUITY;

ACTION POTENTIALS; ANIMALS; CHICKENS; DIFFERENTIAL THRESHOLD; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; EQUIPMENT FAILURE ANALYSIS; EVOKED POTENTIALS; NERVE NET; PROSTHESES AND IMPLANTS; REPRODUCIBILITY OF RESULTS; RETINA; SENSITIVITY AND SPECIFICITY; SPACE PERCEPTION;

EID: 33847611213     PISSN: 17412560     EISSN: 17412552     Source Type: Journal    
DOI: 10.1088/1741-2560/4/1/S02     Document Type: Article

References (37)

1. Chow A Y Artificial retina device US Patent 5,016,633
2. Chow A Y and Chow V Y 1997 Subretinal electrical stimulation of the rabbit retina Neurosci. Lett. 225 13-6
3. Chow A Y, Chow V Y, Packo K H, Pollack J S, Peyman G A and Schuchard R 2004 The artificial silicon retina microchip for the treatment of vision loss from retinitis pigmentosa Arch. Ophthalmol. 122 460-9
4. Chow A Y, Pardue M T, Chow V Y, Peyman G A, Liang C, Perlman J I and Peachey N S 2001 Implantation of silicon chip microphotodiode arrays into the cat subretinal space IEEE Trans. Neural Syst. Rehabil. Eng. 9 86-95
5. Dagnelie G 2006 Visual prosthetics 2006: assessment and expectations Expert. Rev. Med. Devices 3 315-25
6. Dowling J 2005 Artificial human vision Expert. Rev. Med. Devices 2 73-85
7. Eckhorn R et al 2006 Visual resolution with retinal implants estimated from recordings in cat visual cortex Vis. Res. 46 2675-90
8. Ehrlich D 1981 Regional specialization of the chick retina as revealed by the size and density of neurons in the ganglion cell layer J. Comp. Neurol. 195 643-57
9. Geisler W S and Davila K D 1985 Ideal discriminators in spatial vision: two-point stimuli J. Opt. Soc. Am. A 2 1483-97
10. Gekeler F, Kobuch K, Schwahn H N, Stett A, Shinoda K and Zrenner E 2004 Subretinal electrical stimulation of the rabbit retina with acutely implanted electrode arrays Graefes Arch. Clin. Exp. Ophthalmol. 242 587-96
11. Holden A L 1982 Electrophysiology of the avian retina Progress in Retinal Research ed N Osborne and G Chader (Oxford: Pergamon)
12. Humayun M S, Prince M, de Juan E Jr, Barron Y, Moskowitz M, Klock I B and Milam A H 1999 Morphometric analysis of the extramacular retina from postmortem eyes with retinitits pigmentosa Invest. Ophthalmol. Vis. Sci. 40 143-8
13. Humayun M S et al 2003 Visual perception in a blind subject with a chronic microelectronic retinal prosthesis Vis. Res. 43 2573-81
14. Jensen R J and Rizzo J F III 2006 Thresholds for activation of rabbit retinal ganglion cells with a subretinal electrode Exp. Eye. Res. 83 367-73
15. Jones B W and Marc R E 2005 Retinal remodeling during retinal degeneration Exp. Eye. Res. 81 123-37
16. Kalloniatis M and Luu C 2005 Webvision: Part IX. Psychophysics of Vision http://webvision.med.utah.edu/Psych1.html
17. Kuffler S W 1953 Discharge patterns and functional organization of mammalian retina J. Neurophysiol. 16 37-68
18. Li L, Hayashida Y and Yagi T 2005 Temporal properties of retinal ganglion cell responses to local transretinal current stimuli in the frog retina Vis. Res. 45 263-73
19. Rizzo J F III, Wyatt J, Loewenstein J, Kelly S and Shire D 2003 Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials Invest. Ophthalmol. Vis. Sci. 44 5362-9
20. Rodieck R W 1998 The First Steps in Seeing (Sunderland: Sinauer Associates)
21. Sakmann B and Creutzfeldt O D 1969 Scotopic and mesopic light adaption in the cat's retina Pflügers Archiv. 313 168-85
22. Santos A, Humayun M S, de Juan E Jr, Greenberg R J, Marsh M J, Klock I B and Milam A H 1997 Preservation of the inner retina in retinitis pigmentosa: a morphometric analysis Arch. Ophthalmol. 115 511-5
23. Schwahn H N, Gekeler F, Kohler K, Kobuch K, Sachs H G, Schulmeyer F, Jakob W, Gabel V P and Zrenner E 2001 Studies on the feasibility of a subretinal visual prosthesis: data from Yucatan micropig and rabbit Graefes Arch. Clin. Exp. Ophthalmol. 239 961-7
24. Stelzle M, Stett A, Brunner B, Graf M and Nisch W 2001 Electrical properties of micro-photodiode arrays for use as artificial retina implant Biomed. Microdev. 3 133-42
25. Stett A 2003 Retinal prothesis: assessment of the quality of seeing achievable by subretinal electrical stimulation Proc. 4th MATHMOOD Vienna ed I Troch and F Breitenecker (Vienna: ARGESIM, Verlag) pp 1614-8
26. Stett A, Barth W, Weiss S, Haemmerle H and Zrenner E 2000 Electrical multisite stimulation of the isolated chicken retina Vis. Res. 40 1785-95
27. Stett A and Herrmann T 2000 Assessment of the quality of seeing achievable by subretinal prostheses Invest. Ophthalmol. Vis. Sci. 41 Abstract no. 4569
28. Stett A, Libal J and Herrmann T 2001 Experiments with photonic and electrical stimulation of chicken retina concerning object localization capability achievable with subretinal implants Invest. Ophthalml. Vis. Sci. 42 S815 Abstract no. 4373
29. Stett A and Schwenger D 2006 Spatial sensitivity of ganglion cells in RCS rat retina to subretinal electrical stimulation with line electrodes Invest. Ophthalmol. Vis. Sci. 47 E-Abstract 3170
30. Toet A and Koenderink J J 1987 Two-point resolution near detection threshold J. Opt. Soc. Am. A 4 1448-54
31. Wassle H and Creutzfeldt O D 1973 Spatial resolution in visual system: a theoretical and experimental study on single units in the cat's lateral geniculate body J. Neurophysiol. 36 13-27
32. Weiland J D, Liu W and Humayun M S 2005 Retinal prosthesis Annu. Rev. Biomed. Eng. 7 361-401
33. Weiss S, Herrmann T, Stett A, Zrenner E and Haemmerle H 1999 Analysis of field potentials and spike patterns evoked by local electrical stimulation of the chicken retina Retinal Degenerative Diseases and Experimental Therapy ed J G Hollyfield et al (Dordrecht/New York: Kluwer Academic/Plenum) pp 407-16
34. Zrenner E 2002 Will retinal implants restore vision? Science 295 1022-5
35. Zrenner E et al 1997 The development of subretinal microphotodiodes for replacement of degenerated photoreceptors Ophthalmic Res. 29 269-80
36. Zrenner E, Besch D, Bartz-Schmidt K U, Gekeler F, Gabel V P, Kuttenkeuler C, Sachs H, Sailer H, Wilhelm B and Wilke R 2006 Subretinal chronic multi-electrode arrays implanted in blind patients Invest. Ophthalmol. Vis. Sci. 47 E-Abstract 1538
37. Zrenner E, Stett A, Weiss S, Aramant R B, Guenther E, Kohler K, Miliczek K D, Seiler M J and Haemmerle H 1999 Can subretinal microphotodiodes successfully replace degenerated photoreceptors? Vis. Res. 39 2555-67