ACCURACY;
ALTERNATIVE HYPOTHESIS;
BILE DUCT CANCER;
CANCER GROWTH;
CANCER SURVIVAL;
CLINICAL TRIAL;
CONTROLLED CLINICAL TRIAL;
EDITORIAL;
HEALTH CARE ORGANIZATION;
HUMAN;
MESOTHELIOMA;
OUTCOME ASSESSMENT;
PRIORITY JOURNAL;
RANDOMIZED CONTROLLED TRIAL;
SURVIVAL;
CLINICAL TRIALS, PHASE II;
HUMANS;
MEDICAL ONCOLOGY;
MODELS, THEORETICAL;
NEOPLASMS;
RANDOMIZED CONTROLLED TRIALS;
RESEARCH DESIGN;
The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent
Gehan EA. The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent. J Chronic Dis 1961;13:346-53.
Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents
Ratain MJ, Mick R, Schilsky RL, Siegler M. Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents. J Natl Cancer Inst 1993;85:1637-43.
Setting the bar in phase II trials: The use of historical data for determining "go/no go" decision for definitive phase III testing
Vickers AJ, Ballen V, Scher HI. Setting the bar in phase II trials: the use of historical data for determining "go/no go" decision for definitive phase III testing. Clin Cancer Res 2007;13:972-6.