Solid lipid microparticles containing loratadine prepared using a Micromixer

Journal of Microencapsulation

Volumn 23, Issue 8, 2006, Pages 823-831

  Milak, Spomenka ^a,b   Medlicott, Natalie ^b   Tucker, Ian ^b  

^a PLIVA CROATIA LTD   (Croatia)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Micromixer; Solid lipid microparticles; Taste masking

Indexed keywords

GLYCEROL PALMITOSTEARATE; LIPID; LORATADINE; MICROSPHERE; WATER;

AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); DIFFERENTIAL SCANNING CALORIMETRY; DRUG DOSAGE FORM; DRUG RELEASE; DRUG SOLUBILITY; ENCAPSULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIPOPHILICITY; MICROSCOPY; PARTICLE SIZE; PHASE PARTITIONING; SALIVA; SIMULATION; SLOW RELEASE FORMULATION; STOMACH PH; SURFACE PROPERTY; SUSPENSION; TASTE;

CALORIMETRY, DIFFERENTIAL SCANNING; CAPSULES; DIGLYCERIDES; LIPIDS; LORATADINE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE;

EID: 33847400535     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/09687860600945750     Document Type: Article

References (10)

1. Dollery, C. (1999) Therapeutic drugs, Churchill Livingstone, Edinburgh
2. Evrard, B.,.Amighi, K.,.Beten, D.,.Delattre, L. and Moes, AJ (1999) Influence of melting and rheological properties of fatty binders on the melt granulation process in a high-shear mixer. Drug Development in Industrial Pharmaceutics, 25, pp. 1177-1184.
3. Lu, MF,.Borodkin, S.,.Woodward, L.,.Diesner, C.,.Hernandez, L. and Vadnere, M. (1991) A polymer carrier system for taste masking of macrolide antibiotics. Pharmaceutical Research, 8, pp. 706-712.
4. Milak, S. (2002) Solid lipid microparticles for taste-masking prepared by Micromixer. University of Otago, Dunedin, New Zealand
5. (1899)
6. Reithmeier, H.,.Herrmann, J. and Gopferich, A. (2001) Development and characterization of lipid microparticles as a drug carrier for somatostatin. International Journal of Pharmaceutics, 218, pp. 133-143.
7. Reithmeier, H.,.Herrmann, J. and Gopferich, A. (2001) Lipid microparticles as a parenteral controlled release device for peptides. Journal of Controlled Release, 73, pp. 339-350.
8. Sugao, H.,.Yamazaki, S.,.Shiozawa, H. and Yano, K. (1998) Taste masking of bitter drug powder without loss of bioavailability by heat treatment of wax-coated microparticles. Journal of Pharmaceutical Sciences, 87, pp. 96-100.
9. Yajima, T.,.Nogata, A.,.Demachi, M.,.Umeki, N.,.Itai, S.,.Yunoki, N. and Nemeto, M. (1996) Particle design for taste-masking using a spray-congealing technique. Chemical and Pharmaceutical Bulletin, 44, pp. 187-191.
10. Yajima, T.,.Umeki, N. and Itai, S. (1999) Optimum spray congealing conditions for masking the bitter taste of clarithromycin in wax matrix. Chemical and Pharmaceutical Bulletin, 47, pp. 220-225.