메뉴 건너뛰기




Volumn 12, Issue 1, 2007, Pages 15-24

The development of artificial neural networks to predict virological response to combination HIV therapy

(16)  Larder, Brendan a   Wang, Dechao a   Revell, Andrew a   Montaner, Julio b   Harrigan, Richard b   De Wolf, Frank c   Lange, Joep d   Wegner, Scott e   Ruiz, Lidia f   Pérez Elías, María Jésus g   Emery, Sean h   Gatell, Jose i   Monforte, Antonella D'Arminio j   Torti, Carlo k   Zazzi, Maurizio l   Lane, Clifford m  


Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; DIDANOSINE; EFAVIRENZ; INDINAVIR; LAMIVUDINE; LOPINAVIR; NELFINAVIR; NEVIRAPINE; RITONAVIR; SAQUINAVIR; STAVUDINE; TENOFOVIR; ZIDOVUDINE;

EID: 33847375483     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (65)

References (41)
  • 1
    • 0347995130 scopus 로고    scopus 로고
    • Treatment of antiretroviral-drug-resistant HIV-1 infection
    • Deeks SG. Treatment of antiretroviral-drug-resistant HIV-1 infection. Lancet 2003; 362:2002-2011.
    • (2003) Lancet , vol.362 , pp. 2002-2011
    • Deeks, S.G.1
  • 2
    • 0038234808 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel
    • Hirsch MS, Brun-Vezinet F, Clotet B, et al. Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel. Clin Infect Dis 2003; 37:113-128.
    • (2003) Clin Infect Dis , vol.37 , pp. 113-128
    • Hirsch, M.S.1    Brun-Vezinet, F.2    Clotet, B.3
  • 3
    • 33847351494 scopus 로고    scopus 로고
    • Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents 2006, Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Washington, DC: Department of Health and Human Services
    • Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents (2006). Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Washington, DC: Department of Health and Human Services.
  • 4
    • 19944403922 scopus 로고    scopus 로고
    • Updated European recommendations for the clinical use of HIV drug resistance testing
    • Vandamme AM, Sönnerborg A, Ait-Khaled M, et al. Updated European recommendations for the clinical use of HIV drug resistance testing. Antivir Ther 2004; 6:829-848
    • (2004) Antivir Ther , vol.6 , pp. 829-848
    • Vandamme, A.M.1    Sönnerborg, A.2    Ait-Khaled, M.3
  • 5
    • 1842863049 scopus 로고    scopus 로고
    • Genotypic resistance tests in the management of the HIV-infected patient at virological failure
    • Aceti A, Carosi G. Genotypic resistance tests in the management of the HIV-infected patient at virological failure. Scand J Infect Dis Suppl 2003; 35 Suppl 106:61-66.
    • (2003) Scand J Infect Dis Suppl , vol.35 , Issue.SUPPL. 106 , pp. 61-66
    • Aceti, A.1    Carosi, G.2
  • 6
    • 1242320996 scopus 로고    scopus 로고
    • Genotypic resistance tests for the management of structured therapeutic interruptions after multiple drug failure
    • Moroni M, Monforte AD. Genotypic resistance tests for the management of structured therapeutic interruptions after multiple drug failure. Scand J Infect Dis Suppl 2003; 35 Suppl 106:79-81.
    • (2003) Scand J Infect Dis Suppl , vol.35 , Issue.SUPPL. 106 , pp. 79-81
    • Moroni, M.1    Monforte, A.D.2
  • 7
    • 2942596050 scopus 로고    scopus 로고
    • Clinical management of treatment-experienced, HIV-infected patients with the fusion inhibitor enfuvirtide: Consensus recommendations
    • Clotet B, Raffi F, Cooper D, et al. Clinical management of treatment-experienced, HIV-infected patients with the fusion inhibitor enfuvirtide: consensus recommendations. AIDS 2004; 18:1137-1146.
    • (2004) AIDS , vol.18 , pp. 1137-1146
    • Clotet, B.1    Raffi, F.2    Cooper, D.3
  • 8
    • 9244242009 scopus 로고    scopus 로고
    • An algorithm-based genotypic resistance score is associated with clinical outcome in HIV-1-infected adults on antiretroviral therapy
    • Ormaasen V, Sandvik L, Asjo B, Holberg-Petersen M, Gaarder P, Bruun J. An algorithm-based genotypic resistance score is associated with clinical outcome in HIV-1-infected adults on antiretroviral therapy. HIV Med 2004; 5:400-406.
    • (2004) HIV Med , vol.5 , pp. 400-406
    • Ormaasen, V.1    Sandvik, L.2    Asjo, B.3    Holberg-Petersen, M.4    Gaarder, P.5    Bruun, J.6
  • 9
    • 3042812835 scopus 로고    scopus 로고
    • Simple linear model provides highly accurate genotypic predictions of HIV-1 drug resistance
    • Wang K, Jenwitheesuk E, Samudrala R, Mittler JE. Simple linear model provides highly accurate genotypic predictions of HIV-1 drug resistance. Antivir Ther 2004; 9:343-352.
    • (2004) Antivir Ther , vol.9 , pp. 343-352
    • Wang, K.1    Jenwitheesuk, E.2    Samudrala, R.3    Mittler, J.E.4
  • 10
    • 0346252370 scopus 로고    scopus 로고
    • Variety of interpretation systems for human immunodeficiency virus type 1 genotyping: Confirmatory information or additional confusion?
    • Sturmer M, Doerr HW, Preiser W. Variety of interpretation systems for human immunodeficiency virus type 1 genotyping: confirmatory information or additional confusion? Curr Drug Targets Infect Disord 2003; 3:373-382.
    • (2003) Curr Drug Targets Infect Disord , vol.3 , pp. 373-382
    • Sturmer, M.1    Doerr, H.W.2    Preiser, W.3
  • 11
    • 0000240637 scopus 로고    scopus 로고
    • Resistance assay interpretation systems vary widely in method and approach
    • Schapiro JM, De Luca A, Harrigan PR, et al. Resistance assay interpretation systems vary widely in method and approach. Antivir Ther 2001; 6 Suppl 1:131.
    • (2001) Antivir Ther , vol.6 , Issue.SUPPL. 1 , pp. 131
    • Schapiro, J.M.1    De Luca, A.2    Harrigan, P.R.3
  • 12
    • 4444319238 scopus 로고    scopus 로고
    • Correlation between rules-based interpretation and virtual phenotype interpretation of HIV-1 genotypes for predicting drug resistance in HIV-infected individuals
    • Gallego O, Martin-Carbonero L, Aguero J, de Mendoza C, Corral A, Soriano V. Correlation between rules-based interpretation and virtual phenotype interpretation of HIV-1 genotypes for predicting drug resistance in HIV-infected individuals. J Virol Methods 2004; 121:115-118.
    • (2004) J Virol Methods , vol.121 , pp. 115-118
    • Gallego, O.1    Martin-Carbonero, L.2    Aguero, J.3    de Mendoza, C.4    Corral, A.5    Soriano, V.6
  • 13
    • 0043092351 scopus 로고    scopus 로고
    • Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes
    • Beerenwinkel N, Daumer M, Oette M, et al. Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes. Nucleic Acids Res 2003; 31:3850-3855.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3850-3855
    • Beerenwinkel, N.1    Daumer, M.2    Oette, M.3
  • 14
    • 0000068643 scopus 로고    scopus 로고
    • Online comparison of HIV-1 drug resistance algorithms identifies rates and causes of discordant interpretations
    • Shafer RW, Gonzales MJ, Brun-Vezinet F. Online comparison of HIV-1 drug resistance algorithms identifies rates and causes of discordant interpretations. Antivir Ther 2001; 6 Suppl 1:101.
    • (2001) Antivir Ther , vol.6 , Issue.SUPPL. 1 , pp. 101
    • Shafer, R.W.1    Gonzales, M.J.2    Brun-Vezinet, F.3
  • 15
    • 0041314116 scopus 로고    scopus 로고
    • Comparison between rules-based human immunodeficiency virus type 1 genotype interpretations and real or virtual phenotype: Concordance analysis and correlation with clinical outcome in heavily treated patients
    • for the GenPherex Group of the MaSTeR Cohort
    • Torti C, Quiros-Roldan E, Keulen W, et al. for the GenPherex Group of the MaSTeR Cohort. Comparison between rules-based human immunodeficiency virus type 1 genotype interpretations and real or virtual phenotype: concordance analysis and correlation with clinical outcome in heavily treated patients. J Infect Dis 2003; 188:194-201
    • (2003) J Infect Dis , vol.188 , pp. 194-201
    • Torti, C.1    Quiros-Roldan, E.2    Keulen, W.3
  • 16
    • 0042154495 scopus 로고    scopus 로고
    • Comparison of nine resistance interpretation systems for HIV-1 genotyping
    • Sturmer M, Doerr HW, Staszewski S, Preiser W. Comparison of nine resistance interpretation systems for HIV-1 genotyping. Antivir Ther 2003; 8:239-244.
    • (2003) Antivir Ther , vol.8 , pp. 239-244
    • Sturmer, M.1    Doerr, H.W.2    Staszewski, S.3    Preiser, W.4
  • 17
    • 0038238324 scopus 로고    scopus 로고
    • Variable prediction of antiretroviral treatment outcome by different systems for interpreting genotypic human immunodeficiency virus type 1 drug resistance
    • De Luca A, Cingolani A, Di Giambenedetto S, et al. Variable prediction of antiretroviral treatment outcome by different systems for interpreting genotypic human immunodeficiency virus type 1 drug resistance. J Infect Dis 2003; 15:1934-1943.
    • (2003) J Infect Dis , vol.15 , pp. 1934-1943
    • De Luca, A.1    Cingolani, A.2    Di Giambenedetto, S.3
  • 18
    • 27744541149 scopus 로고    scopus 로고
    • Computational models for the design of effective therapies against drug resistant HIV strains
    • Beerenwinkel N, Sing T, Lengauer T, et al. Computational models for the design of effective therapies against drug resistant HIV strains. Bioinformatics 2005; 21: 3943-3950.
    • (2005) Bioinformatics , vol.21 , pp. 3943-3950
    • Beerenwinkel, N.1    Sing, T.2    Lengauer, T.3
  • 19
    • 0141724633 scopus 로고    scopus 로고
    • Enhanced prediction of lopinavir resistance from genotype by use of artificial neural networks
    • Wang D, Larder B. Enhanced prediction of lopinavir resistance from genotype by use of artificial neural networks. J Infect Dis 2003; 188:653-660.
    • (2003) J Infect Dis , vol.188 , pp. 653-660
    • Wang, D.1    Larder, B.2
  • 20
    • 0037062513 scopus 로고    scopus 로고
    • Diversity and complexity of HIV-1 drug restiance: A bioinformatics approach to predicting pnenotype form genotype
    • Beerenwinkel N, Schmidt B, Walter H, et al. Diversity and complexity of HIV-1 drug restiance: a bioinformatics approach to predicting pnenotype form genotype. Proc Natl Acad Sci 2002; 99:8271-8276.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 8271-8276
    • Beerenwinkel, N.1    Schmidt, B.2    Walter, H.3
  • 21
    • 0002344144 scopus 로고    scopus 로고
    • Quantitative prediction of HIV-1 phenotypic drug resistance from genotypes: The virtual phenotype (VirtualPhenotype)
    • Larder BA, Kemp SD, Hertogs K. Quantitative prediction of HIV-1 phenotypic drug resistance from genotypes: the virtual phenotype (VirtualPhenotype). Antivir Ther 2000; 5 Suppl 3:49.
    • (2000) Antivir Ther , vol.5 , Issue.SUPPL. 3 , pp. 49
    • Larder, B.A.1    Kemp, S.D.2    Hertogs, K.3
  • 22
    • 4344701042 scopus 로고    scopus 로고
    • Clinically validated genotype analysis: Guiding principles and statistical concerns
    • Brun-Vezinet F, Costagliola D, Khaled MA, et al. Clinically validated genotype analysis: guiding principles and statistical concerns. Antivir Ther 2004; 9:465-478.
    • (2004) Antivir Ther , vol.9 , pp. 465-478
    • Brun-Vezinet, F.1    Costagliola, D.2    Khaled, M.A.3
  • 23
    • 29144446349 scopus 로고    scopus 로고
    • Estimation of phenotypic clinical cut-offs for VirtualPhenotype through meta analyses of clinical trial and cohort data
    • Bachelor L, Winter B, Nauwelauers D, et al. Estimation of phenotypic clinical cut-offs for VirtualPhenotype through meta analyses of clinical trial and cohort data. Antivir Ther 2004; 9: S154.
    • (2004) Antivir Ther , vol.9
    • Bachelor, L.1    Winter, B.2    Nauwelauers, D.3
  • 24
    • 4344623482 scopus 로고    scopus 로고
    • Weighted phenotypic susceptibility scores are predictive of the HIV-1 RNA response in protease inhibitor-experienced HIV-1-infected subjects
    • Swanstrom R, Bosch R, Katzenstein, D, et al. Weighted phenotypic susceptibility scores are predictive of the HIV-1 RNA response in protease inhibitor-experienced HIV-1-infected subjects. J Infect Dis 2004; 190:886-893.
    • (2004) J Infect Dis , vol.190 , pp. 886-893
    • Swanstrom, R.1    Bosch, R.2    Katzenstein, D.3
  • 25
    • 0005201858 scopus 로고    scopus 로고
    • Collaborative HIV resistance-response database: Sample size for detection of relationships between HIV-1 genotype and HIV-1 RNA response using a non-parametric approach
    • DiRienzo G and DeGruttola V. Collaborative HIV resistance-response database: sample size for detection of relationships between HIV-1 genotype and HIV-1 RNA response using a non-parametric approach. Antivir Ther 2002; 7:S71.
    • (2002) Antivir Ther , vol.7
    • DiRienzo, G.1    DeGruttola, V.2
  • 26
    • 80052921423 scopus 로고    scopus 로고
    • The international HIV resistance response database initiative: A new global collaborative approach to relating viral genotype treatment to clinical outcome
    • Larder, BA, DeGruttola, V, Hammer, et al. The international HIV resistance response database initiative: a new global collaborative approach to relating viral genotype treatment to clinical outcome. Antivir Ther 2002; 7:S84.
    • (2002) Antivir Ther , vol.7
    • Larder, B.A.1    DeGruttola, V.2    Hammer3
  • 27
    • 4444360157 scopus 로고    scopus 로고
    • Predicting risk of coronary artery disease from DNA microarray-based genotyping using neural networks and other statistical analysis tool
    • Tham CK, Heng CK, Chin WC. Predicting risk of coronary artery disease from DNA microarray-based genotyping using neural networks and other statistical analysis tool. J Bioinform Comput Biol 2003; 1:521-539.
    • (2003) J Bioinform Comput Biol , vol.1 , pp. 521-539
    • Tham, C.K.1    Heng, C.K.2    Chin, W.C.3
  • 28
    • 0346848886 scopus 로고    scopus 로고
    • Heckerling PS, Gerber BS, Tape TG, Wigton RS. Use of genetic algorithms for neural networks to predict community-acquired pneumonia. Artif Intell Med 2004; 30:71-84.
    • Heckerling PS, Gerber BS, Tape TG, Wigton RS. Use of genetic algorithms for neural networks to predict community-acquired pneumonia. Artif Intell Med 2004; 30:71-84.
  • 29
    • 1842435248 scopus 로고    scopus 로고
    • European Consortium for IDDM Genome Studies. Novel analytical methods applied to type 1 diabetes genome-scan data
    • Pociot F, Karlsen AE, Pedersen CB, Aalund M, Nerup J, European Consortium for IDDM Genome Studies. Novel analytical methods applied to type 1 diabetes genome-scan data. Am J Hum Genet 2004; 74:647-660.
    • (2004) Am J Hum Genet , vol.74 , pp. 647-660
    • Pociot, F.1    Karlsen, A.E.2    Pedersen, C.B.3    Aalund, M.4    Nerup, J.5
  • 30
    • 0034213103 scopus 로고    scopus 로고
    • Basic concepts of artificial neural network (ANN) modelling and its application in pharmaceutical research
    • Agatonovic-Kustrin S, Beresford R. Basic concepts of artificial neural network (ANN) modelling and its application in pharmaceutical research. J Pharm Biomed Anal 2000; 22:717-727.
    • (2000) J Pharm Biomed Anal , vol.22 , pp. 717-727
    • Agatonovic-Kustrin, S.1    Beresford, R.2
  • 31
    • 0034909925 scopus 로고    scopus 로고
    • Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients
    • Kempf DJ, Isaacson JD, King MS, et al. Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients. J Virol 2001; 75:7462-7469.
    • (2001) J Virol , vol.75 , pp. 7462-7469
    • Kempf, D.J.1    Isaacson, J.D.2    King, M.S.3
  • 32
    • 4344707784 scopus 로고    scopus 로고
    • Montaner JA neural network model using clinical cohort data accurately predicts virological response and identifies regimens with increased probability of success in treatment failures
    • Wang D, Larder B, Revell A, Harrigan R, Montaner JA neural network model using clinical cohort data accurately predicts virological response and identifies regimens with increased probability of success in treatment failures. Antivir Ther 2003; 8:S112.
    • (2003) Antivir Ther , vol.8
    • Wang, D.1    Larder, B.2    Revell, A.3    Harrigan, R.4
  • 33
    • 34147150585 scopus 로고    scopus 로고
    • Neural network model identified potentially effective drug combinations for patients failing salvage therapy
    • Paris, France, 13-16 July, Poster LB39
    • Larder BA, Wang D, Revell A, Lane C. Neural network model identified potentially effective drug combinations for patients failing salvage therapy. The 2nd IAS Conference on HIV Pathogenesis and Treatment. Paris, France, 13-16 July 2003. Poster LB39.
    • (2003) The 2nd IAS Conference on HIV Pathogenesis and Treatment
    • Larder, B.A.1    Wang, D.2    Revell, A.3    Lane, C.4
  • 34
    • 33444463595 scopus 로고    scopus 로고
    • Accuracy of neural network nodels in predicting HIV treatment response from genotype may depend on diversity as well as size of datasets
    • San Francisco, CA, USA, 8-11 February, Poster 697
    • Larder BA, Wang D, Revell A, Harrigan R, Montaner J, Lane C. Accuracy of neural network nodels in predicting HIV treatment response from genotype may depend on diversity as well as size of datasets. The 11th Conference on Retroviruses and Opportunistic Infections. San Francisco, CA, USA, 8-11 February 2004. Poster 697.
    • (2004) The 11th Conference on Retroviruses and Opportunistic Infections
    • Larder, B.A.1    Wang, D.2    Revell, A.3    Harrigan, R.4    Montaner, J.5    Lane, C.6
  • 35
    • 33847357587 scopus 로고    scopus 로고
    • Revell A, Larder BA, Wang D, et al. Global neural network models are superior to single clinic models as general quantitative predictors of virological treatment response. 3rd IAS Conference on HIV Pathogenesis and Treatment. 24-27 July 2005, Rio de Janeiro, Brazil. Poster WePe12.6C04.
    • Revell A, Larder BA, Wang D, et al. Global neural network models are superior to single clinic models as general quantitative predictors of virological treatment response. 3rd IAS Conference on HIV Pathogenesis and Treatment. 24-27 July 2005, Rio de Janeiro, Brazil. Poster WePe12.6C04.
  • 36
    • 0042374161 scopus 로고    scopus 로고
    • Low frequency of non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant variants contribute to failure of efavirenz-containing regimens in NNRTI-experienced patients with negative standard genotypes of NNRTI mutations
    • for the ACTG 398 Study Team
    • Mellors J, Palmer S, Nissley D, et al. for the ACTG 398 Study Team. Low frequency of non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant variants contribute to failure of efavirenz-containing regimens in NNRTI-experienced patients with negative standard genotypes of NNRTI mutations. Antivir Ther 2003; 8:S150.
    • (2003) Antivir Ther , vol.8
    • Mellors, J.1    Palmer, S.2    Nissley, D.3
  • 37
    • 33847420758 scopus 로고    scopus 로고
    • Previous drug exposure data significantly increase the accuracy of artificial neural networks in predicting virological response to combination therapy
    • Larder B, Wang D, Revell A, Harrigan R, Montaner J, Lane C. Previous drug exposure data significantly increase the accuracy of artificial neural networks in predicting virological response to combination therapy. Antivir Ther 2004; 9:S123.
    • (2004) Antivir Ther , vol.9
    • Larder, B.1    Wang, D.2    Revell, A.3    Harrigan, R.4    Montaner, J.5    Lane, C.6
  • 38
    • 33847421223 scopus 로고    scopus 로고
    • Treatment history, CD4 count but not previous genotype improves the accuracy of predicting virological response to HIV therapy
    • Washington DC, USA, 16-19 December, Poster
    • Larder B A, Wang D, Revell A, et al. Treatment history, CD4 count but not previous genotype improves the accuracy of predicting virological response to HIV therapy. 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington DC, USA, 16-19 December 2005. Poster H-1051.
    • (2005) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Larder, B.A.1    Wang, D.2    Revell, A.3
  • 39
    • 33847371012 scopus 로고    scopus 로고
    • Global neural network models are superior to single clinic models as general quantitative predictors of virological treatment response
    • Wegner S, Larder BA, Wang D, et al. Global neural network models are superior to single clinic models as general quantitative predictors of virological treatment response. Antivir Ther 2005; 10:S58.
    • (2005) Antivir Ther , vol.10
    • Wegner, S.1    Larder, B.A.2    Wang, D.3
  • 40
    • 33847338720 scopus 로고    scopus 로고
    • A randomised trial comparing genotypic and virtual phenotypic interpretation of HIV drug resistance: The CREST study PLoS
    • Hales G, Birch C, Crowe S, et al. A randomised trial comparing genotypic and virtual phenotypic interpretation of HIV drug resistance: The CREST study PLoS Clin Trials 2006; 1:e18.
    • (2006) Clin Trials , vol.1
    • Hales, G.1    Birch, C.2    Crowe, S.3
  • 41


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.