Survival related to plasma C-reactive-protein in nonagenarlans is modified by apolipoprotein E genotype [9]

Clinical Chemistry

Volumn 53, Issue 2, 2007, Pages 365-367

  Lehtimäki, Terho ^a   Hervonen, Antti ^b   Rontu, Riikka ^a   Karhunen, Pekka ^c   Jylhä, Marja ^b   Hurme, Mikko ^c  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TAMPERE   (Finland)

^c UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; C REACTIVE PROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLASMA PROTEIN;

ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; GENOTYPE; HETEROZYGOTE DETECTION; HUMAN; LETTER; MORTALITY; SURVIVAL RATE;

AGED, 80 AND OVER; APOLIPOPROTEINS E; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; FEMALE; GENOTYPE; HUMANS; MALE; MORTALITY; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; SURVIVAL ANALYSIS;

EID: 33847345977     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.075002     Document Type: Letter

References (5)

1. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003;107:363-9.
2. Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988;240:622-30.
3. März W, Scharnagl H, Hoffmann MM, Boehm BO, Winkelmann BR. The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study). Eur Heart J 2004;25:2109-19.
4. Rontu R, Ojala P, Hervonen A, Goebler S, Karhunen PJ, Nikkilä M, et al. Apolipoprotein E genotypes relates to plasma C-reactive protein, lipid levels and longevity in nonagenarians. Clin Endocrinol (Oxf) 2006;64:265-70.
5. Zwaka TP, Hombach V, Torzewski J. C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis. Circulation 2001;103:1194-7.