Rectal cancer delivery of radiotherapy in adequate time and with adequate dose is influenced by treatment center, treatment schedule, and gender and is prognostic parameter for local control: Results of study CAO/ARO/AIO-94

International Journal of Radiation Oncology Biology Physics

Volumn 67, Issue 4, 2007, Pages 1008-1019

  Fietkau, Rainer ^a   Rödel, Claus ^b   Hohenberger, Werner ^b   Raab, Rudolf ^c   Hess, Clemens ^d   Liersch, Torsten ^d   Becker, Heinz ^d   Wittekind, Christian ^e   Hutter, Matthias ^f   Hager, Eva ^g   Karstens, Johann ^h   Ewald, Hermann ⁱ   Christen, Norbert ^j   Jagoditsch, Michael ^k   Martus, Peter ^l   Sauer, Rolf ^b  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c KLINIKUM OLDENBURG   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e UNIVERSITY OF LEIPZIG   (Germany)

^f KRANKENHAUS NORDWEST   (Germany)

^g Krankenhaus der Elisabethinen Klagenfurt   (Austria)

^h LEIBNIZ UNIVERSITY HANNOVER   (Germany)

ⁱ UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^j ACADEMIC TEACHING HOSPITAL DRESDEN FRIEDRICHSTADT   (Germany)

^k Department of Surgery   (Austria)

^l CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

more..

Author keywords

Adjuvant chemoradiotherapy; Delivery of radiotherapy; Locoregional recurrence rate; Neoadjuvant chemoradiotherapy; Rectal cancer

Indexed keywords

DISEASE CONTROL; DRUG DOSAGE; PATHOLOGY; PATIENT TREATMENT; RADIATION; TUMORS;

ADJUVANT CHEMORADIOTHERAPY; DELIVERY OF RADIOTHERAPY; LOCOREGIONAL RECURRENCE RATE; NEOADJUVANT CHEMORADIOTHERAPY; RECTAL CANCER;

RADIOTHERAPY;

ANTINEOPLASTIC AGENT;

ADULT; AGE; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CONTROL; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DOSIMETRY; FEMALE; GENDER; GERMANY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE DISTRIBUTION; RECTUM CANCER; TREATMENT INDICATION; TREATMENT OUTCOME;

AGED; ANALYSIS OF VARIANCE; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; SEX FACTORS; TIME FACTORS;

EID: 33847323077     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.10.020     Document Type: Article

References (21)

1. Sauer R., Becker H., Hohenberger W., et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351 (2004) 1731-1740
2. Hermanek P., Wiebelt H., Staimmer D., et al. the German Study Group Colo-Rectal Carcinoma. Prognostic factors of rectum carcinoma-Experience of the German Multicentre Study SGCRC. Tumori 81 (1995) 60-64
3. Hermanek P. Impact of surgeon's technique on outcome after treatment of rectal carcinoma. Dis Colon Rectum 42 (1999) 559-562
4. Porter G.A., Soskolne C.L., Yakimets W.W., et al. Surgeon-related factors and outcome in rectal cancer. Ann Surg 227 (1998) 157-167
5. Schrag D., Panageas K.S., Riedel E., et al. Hospital and surgeon procedure volume as predictors of outcome following rectal cancer resection. Ann Surg 236 (2002) 583-592
6. Stocchi L., Nelson H., Sargent D.J., et al. Impact of surgical and pathologic variables in rectal cancer: A United States community and cooperative group report. J Clin Oncol 19 (2001) 3895-3902
7. Beart R.W., Steele Jr. G.D., Menck H.R., et al. Management and survival of patients with adenocarcinoma of the colon and rectum: A national survey of the Commission on Cancer. J Am Coll Surg 181 (1995) 225-236
8. Engel J., Kerr J., Eckel R., et al. Quality of treatment in routine care in a population sample of rectal cancer patients. Acta Oncol 44 (2005) 65-74
9. Harling H., Bulow S., Moller L.N., et al. Hospital volume and outcome of rectal cancer surgery in Denmark, 1994-99. Colorectal Dis 7 (2005) 90-95
10. Simons A.J., Ker R., Groshen S., et al. Variations in treatment of rectal cancer: The influence of hospital type and caseload. Dis Colon Rectum 40 (1997) 641-646
11. Schroen A.T., and Cress R.D. Use of surgical procedures and adjuvant therapy in rectal cancer treatment: A population-based study. Ann Surg 234 (2001) 641-651
12. Marusch F., Koch A., Schmidt U., et al. Hospital caseload and the results achieved in patients with rectal cancer. Br J Surg 88 (2001) 1397-1402
13. Hermanek P, Sobin LH, editors, for the International Union Against Cancer. TNM classification of malignant tumors. 4th ed., 2nd revision. New York: Springer; 1992.
14. Sauer R., Fietkau R., Wittekind C., et al. Adjuvant versus neoadjuvant radiochemotherapy for locally advanced rectal cancer: A progress report of a phase-III randomized trial (protocol CAO/ARO/AIO-94). Strahlenther Onkol 177 (2001) 173-181
15. Wolmark N., Wieand H.S., Hyams D.M., et al. Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project protocol R-02J. Natl Cancer Inst 92 (2000) 388-396
16. Hodgson D.C., Zhang W., Zaslavsky A.M., et al. Relation of hospital volume to colostomy rates and survival for patients with rectal cancer. J Natl Cancer Inst 95 (2003) 708-716
17. Ayanian J.Z., Zaslavsky A.M., Fuchs C.S., et al. Use of adjuvant chemotherapy and radiation therapy for colorectal cancer in a population-based cohort. J Clin Oncol 21 (2003) 1293-1300
18. Fietkau R., Zettl H., Klöcking S., and Kundt G. Incidence, therapy and prognosis of colorectal cancer in different age groups: A population-based cohort study of the Rostock Cancer Registry. Strahlenther Onkol 180 (2004) 478-487
19. Meyerhardt J.A., Tepper J.E., Niedzwiecki D., et al. Impact of hospital procedure volume on surgical operation and long-term outcomes in high-risk curatively resected rectal cancer: Findings from the Intergroup 0114 Study. J Clin Oncol 22 (2004) 166-174
20. Wulf J., Kramer K., van Aaken C., et al. Outcome of postoperative treatment for rectal cancer UICC stage II and III in day-to-day clinical practice: Results from a retrospective quality control analysis in six institutions in North Bavaria (Germany). Strahlenther Onkol 180 (2004) 5-14
21. Herrmann T., and Baumann M. Prolongation of latency or overall treatment time by unplanned radiation pauses: The clinical importance of compensation. Strahlenther Onkol 181 (2005) 65-76