Evaluation of two novel peptide safety markers for exocrine pancreatic toxicity

Toxicological Sciences

Volumn 96, Issue 1, 2007, Pages 184-193

  Walgren, Jennie L ^a   Mitchell, Michael D ^a   Whiteley, Laurence O ^a   Thompson, David C ^a  

^a PFIZER INC   (United States)

Author keywords

Caerulein; CHB; Human; Pancreatitis; Safety biomarkers; SELDI

Indexed keywords

ALBUMIN; AMYLASE; CERULETIDE; CYANOBUTENOL; GLUCOSINOLATE; PEPTIDE; PROTEINASE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; DISEASE SEVERITY; GASTROINTESTINAL TOXICITY; HISTOPATHOLOGY; HUMAN; MALE; MOUSE; NONHUMAN; PANCREAS INJURY; PANCREATITIS; PREDICTION; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; RAT; SENSITIVITY ANALYSIS; SEROLOGY;

ACUTE DISEASE; ALKENES; AMYLASES; ANIMALS; BIOLOGICAL MARKERS; CAERULEIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LIPASE; MALE; MICE; NITRILES; PANCREAS, EXOCRINE; PANCREATITIS; PEPTIDE FRAGMENTS; PREDICTIVE VALUE OF TESTS; PROTEIN ARRAY ANALYSIS; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS;

MUS; RATTUS;

EID: 33847314252     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfl190     Document Type: Article

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