Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor

Journal of Biological Chemistry

Volumn 282, Issue 3, 2007, Pages 1769-1778

  Glerup, Simon ^a   Kløverpris, Søren ^a   Laursen, Lisbeth S ^a   Dagnæs Hansen, Frederik ^a   Thiel, Steffen ^a   Conover, Cheryl A ^b   Oxvig, Claus ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b Mayo Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOAVAILABILITY; DISULFIDE BONDS; GLYCOSAMINOGLYCAN; GROWTH FACTOR-BINDING PROTEINS; HALF LIFE; HUMAN PREGNANCY; METZINCIN METALLOPROTEINASE; PREGNANCY-ASSOCIATED PLASMA PROTEIN; PROTEINASE-INHIBITOR; PROTEOLYTIC CLEAVAGE;

CHEMICAL BONDS; COMPLEXATION; GROWTH KINETICS; HORMONES; MOLECULAR BIOLOGY; PROTEOLYSIS;

ENZYME INHIBITION;

ARGININE; ASPARAGINE; CELL SURFACE PROTEIN; DISULFIDE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HISTIDINE; MAJOR BASIC PROTEIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A; SERINE; SOMATOMEDIN; PROTEINASE INHIBITOR;

AMINO ACID SUBSTITUTION; ARTICLE; BIOAVAILABILITY; CELL SURFACE; COMPARATIVE STUDY; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; DISULFIDE BOND; EMBRYO; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; FEMALE; METABOLISM; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; DISULFIDES; FEMALE; GLYCOSAMINOGLYCANS; HEPARITIN SULFATE; HUMANS; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PROTEASE INHIBITORS; SOMATOMEDINS;

EID: 33847306034     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608454200     Document Type: Article

References (39)

1. Lawrence, J. B., Oxvig, C., Overgaard, M. T., Sottrup-Jensen, L., Gleich, G. J., Hays, L. G., Yates, J. R., III, and Conover, C. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3149-3153
2. Laursen, L. S., Overgaard, M. T., Soe, R., Boldt, H. B., Sottrup-Jensen, L., Giudice, L. C., Conover, C. A., and Oxvig, C. (2001) FEBS Lett. 504, 36-40
3. Bunn, R. C., and Fowlkes, J. L. (2003) Trends Endocrinol. Metab. 14, 176-181
4. Conover, C. A., Faessen, G. F., Ilg, K. E., Chandrasekher, Y. A., Christiansen, M., Overgaard, M. T., Oxvig, C., and Giudice, L. C. (2001) Endocrinology 142, 2155-2158
5. Giudice, L. C., Conover, C. A., Bale, L., Faessen, G. H., Ilg, K., Sun, I., Imani, B., Suen, L. F., Irwin, J. C., Christiansen, M., Overgaard, M. T., and Oxvig, C. (2002) J. Clin. Endocrinol. Metab. 87, 2359-2366
6. Conover, C. A., Bale, L. K., Overgaard, M. T., Johnstone, E. W., Laursen, U. H., Fuchtbauer, E. M., Oxvig, C., and van Deursen, J. (2004) Development 131, 1187-1194
7. Smith, G. C., Stenhouse, E. J., Crossley, J. A., Aitken, D. A., Cameron, A. D., and Connor, J. M. (2002) Nature 417, 916
8. Wald, N. J., Watt, H. C., and Hackshaw, A. K. (1999) N. Engl. J. Med. 341, 461-467
9. Chen, B. K., Leiferman, K. M., Pittelkow, M. R., Overgaard, M. T., Oxvig, C., and Conover, C. A. (2003) J. Clin. Endocrinol. Metab. 88, 4465-4471
10. Bayes-Genis, A., Conover, C. A., Overgaard, M. T., Bailey, K. R., Christiansen, M., Holmes, D. R., Jr., Virmani, R., Oxvig, C., and Schwartz, R. S. (2001) N. Engl. J. Med. 345, 1022-1029
11. Laursen, L. S., Overgaard, M. T., Weyer, K., Boldt, H. B., Ebbesen, P., Christiansen, M., Sottrup-Jensen, L., Giudice, L. C., and Oxvig, C. (2002) J. Biol. Chem. 277, 47225-47234
12. Weyer, K., Overgaard, M. T., Laursen, L. S., Nielsen, C. G., Schmitz, A., Christiansen, M., Sottrup-Jensen, L., Giudice, L. C., and Oxvig, C. (2004) Eur. J. Biochem. 271, 1525-1535
13. Kirkitadze, M. D., and Barlow, P. N. (2001) Immunol. Rev. 180, 146-161
14. Ganesh, V. K., Smith, S. A., Kotwal, G. J., and Murthy, K. H. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 8924-8929
15. Overgaard, M. T., Glerup, S., Boldt, H. B., Rodacker, V., Olsen, I. M., Christiansen, M., Sottrup-Jensen, L., Giudice, L. C., and Oxvig, C. (2004) FEBS Lett. 560, 147-152
16. Glerup, S., Kloverpris, S., and Oxvig, C. (2006) J. Biol. Chem. 281, 31509-31516
17. Glerup, S., Boldt, H. B., Overgaard, M. T., Sottrup-Jensen, L., Giudice, L. C., and Oxvig, C. (2005) J. Biol. Chem. 280, 9823-9832
18. Overgaard, M. T., Sorensen, E. S., Stachowiak, D., Boldt, H. B., Kristensen, L., Sottrup-Jensen, L., and Oxvig, C. (2003) J. Biol. Chem. 278, 2106-2117
19. Oxvig, C., Sand, O., Kristensen, T., Gleich, G. J., and Sottrup-Jensen, L. (1993) J. Biol. Chem. 268, 12243-12246
20. Bonno, M., Oxvig, C., Kephart, G. M., Wagner, J. M., Kristensen, T., Sottrup-Jensen, L., and Gleich, G. J. (1994) Lab. Investig. 71, 560-566
21. Overgaard, M. T., Oxvig, C., Christiansen, M., Lawrence, J. B., Conover, C. A., Gleich, G. J., Sottrup-Jensen, L., and Haaning, J. (1999) Biol. Reprod. 61, 1083-1089
22. Pizzo, S. V. (1989) Am. J. Med. 87, Suppl. 2, S10-S14
23. Sottrup-Jensen, L. (1989) J. Biol. Chem. 264, 11539-11542
24. Oxvig, C., Haaning, J., Hojrup, P., and Sottrup-Jensen, L. (1994) Biochem. Mol. Biol. Int. 33, 329-336
25. Zhuo, L., Hascall, V. C., and Kimata, K. (2004) J. Biol. Chem. 279, 38079-38082
26. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 51-59
27. DuBridge, R. B., Tang, P., Hsia, H. C., Leong, P. M., Miller, J. H., and Calos, M. P. (1987) Mol. Cell. Biol. 7, 379-387
28. Pear, W. S., Nolan, G. P., Scott, M. L., and Baltimore, D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8392-8396
29. Boldt, H. B., Overgaard, M. T., Laursen, L. S., Weyer, K., Sottrup-Jensen, L., and Oxvig, C. (2001) Biochem. J. 358, 359-367
30. Qin, Q. P., Christiansen, M., Oxvig, C., Pettersson, K., Sottrup-Jensen, L., Koch, C., and Norgaard-Pedersen, B. (1997) Clin. Chem. 43, 2323-2332
31. Oxvig, C., Sand, O., Kristensen, T., Kristensen, L., and Sottrup-Jensen, L. (1994) Biochim. Biophys. Acta 1201, 415-423
32. Sottrup-Jensen, L. (1993) Biochem. Mol. Biol. Int. 30, 789-794
33. Laursen, L. S., Overgaard, M. T., Nielsen, C. G., Boldt, H. B., Hopmann, K. H., Conover, C. A., Sottrup-Jensen, L., Giudice, L. C., and Oxvig, C. (2002) Biochem. J. 367, 31-40
34. Swaminathan, G. J., Weaver, A. J., Loegering, D. A., Checkel, J. L., Leonidas, D. D., Gleich, G. J., and Acharya, K. R. (2001) J. Biol. Chem. 276, 26197-26203
35. Dementiev, A., Petitou, M., Herbert, J. M., and Gettins, P. G. (2004) Nat. Struct. Mol. Biol. 11, 863-867
36. Li, W., Johnson, D. J., Esmon, C. T., and Huntington, J. A. (2004) Nat. Struct. Mol. Biol. 11, 857-862
37. Hogg, P. J. (2003) Trends Biochem. Sci. 28, 210-214
38. Imber, M. J., and Pizzo, S. V. (1981) J. Biol. Chem. 256, 8134-8139
39. Overgaard, M. T., Haaning, J., Boldt, H. B., Olsen, I. M., Laursen, L. S., Christiansen, M., Gleich, G. J., Sottrup-Jensen, L., Conover, C. A., and Oxvig, C. (2000) J. Biol. Chem. 275, 31128-31133