Determination of methylmalonic acid and glutaric acid in urine by aqueous-phase derivatization followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry

Journal of Separation Science

Volumn 30, Issue 2, 2007, Pages 266-271

  Li, Ning ^a   Deng, Chunhui ^a   Zhang, Xiangmin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Glutaric acidemia type I; Inborn errors of metabolism; Methylmalonic acidemia; Solid phase microextraction

Indexed keywords

BIOCHEMISTRY; BIOMARKERS; EXTRACTION; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC ACIDS;

AQUEOUS-PHASE DERIVATIZATION; GLUTARIC ACID; METHYLMALONIC ACID; SOLID-PHASE MICROEXTRACTION; URINE;

BODY FLUIDS;

BIOLOGICAL MARKER; CARBOXYLIC ACID; DIETHYL SULFATE; GLUTARIC ACID; METHYLMALONIC ACID; TETRABUTYLAMMONIUM;

AQUEOUS SOLUTION; ARTICLE; DERIVATIZATION; GAS CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN DETERMINATION; PROTEIN ISOLATION; PROTEIN URINE LEVEL; SOLID PHASE MICROEXTRACTION; TEMPERATURE MEASUREMENT; VALIDATION STUDY;

CHROMATOGRAPHY, ION EXCHANGE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUTARATES; HUMANS; METHYLMALONIC ACID; SOLID PHASE MICROEXTRACTION; TEMPERATURE;

EID: 33847304043     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200600296     Document Type: Article

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