The proportion of prostate biopsy tissue with Gleason pattern 4 or 5 predicts for biochemical and clinical outcome after radiotherapy for prostate cancer

International Journal of Radiation Oncology Biology Physics

Volumn 67, Issue 4, 2007, Pages 1082-1087

  D'Ambrosio, David J ^a   Hanlon, Alexandra L ^a   Al Saleem, Tahseen ^a   Feigenberg, Steven J ^a   Horwitz, Eric M ^a   Uzzo, Robert G ^a   Pollack, Alan ^a   Buyyounouski, Mark K ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Gleason pattern; Gleason score; Prostate; PSA; Radiation therapy

Indexed keywords

BIOPSY; ONCOLOGY; PARAMETER ESTIMATION; PATIENT MONITORING; RADIOTHERAPY; TUMORS;

GLEASON PATTERNS; GLEASON SCORES; PROSTATE; PSA;

TISSUE;

BIOCHEMICAL MARKER; PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; BIOCHEMICAL FAILURE; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; DISTANT METASTASIS; FOLLOW UP; GLEASON SCORE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METASTASIS; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE BIOPSY; PROSTATE CANCER; THREE DIMENSIONAL IMAGING; TREATMENT FAILURE; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; TREATMENT OUTCOME;

EID: 33847302011     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.09.050     Document Type: Article

References (26)

1. Gleason D.F., and Mellinger G.T. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol 111 (1974) 58-64
2. Gleason D.F. Classification of prostatic carcinomas. Cancer Chemother Rep 50 (1966) 125-128
3. Epstein J.I., Partin A.W., Sauvageot J., et al. Prediction of progression following radical prostatectomy. A multivariate analysis of 721 men with long-term follow-up. Am J Surg Pathol 20 (1996) 286-292
4. Kupelian P., Katcher J., Levin H., et al. Correlation of clinical and pathologic factors with rising prostate-specific antigen profiles after radical prostatectomy alone for clinically localized prostate cancer. Urology 48 (1996) 249-260
5. Oefelein M.G., Grayhack J.T., and McVary K.T. Survival after radical retropubic prostatectomy of men with clinically localized high grade carcinoma of the prostate. Cancer 76 (1995) 2535-2542
6. Partin A.W., Yoo J., Carter H.B., et al. The use of prostate specific antigen, clinical stage and Gleason score to predict pathological stage in men with localized prostate cancer. J Urol 150 (1993) 110-114
7. Anderson P.R., Hanlon A.L., Horwitz E., et al. Outcome and predictive factors for patients with Gleason score 7 prostate carcinoma treated with three-dimensional conformal external beam radiation therapy. Cancer 89 (2000) 2565-2569
8. Kuban D.A., Thames H.D., Levy L.B., et al. Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era. Int J Radiat Oncol Biol Phys 57 (2003) 915-928
9. Pollack A., Smith L.G., and von Eschenbach A.C. External beam radiotherapy dose response characteristics of 1127 men with prostate cancer treated in the PSA era. Int J Radiat Oncol Biol Phys 48 (2000) 507-512
10. Stamey T.A., McNeal J.E., Yemoto C.M., et al. Biological determinants of cancer progression in men with prostate cancer. JAMA 281 (1999) 1395-1400
11. McNeal J.E., Villers A.A., Redwine E.A., et al. Histologic differentiation, cancer volume, and pelvic lymph node metastasis in adenocarcinoma of the prostate. Cancer 66 (1990) 1225-1233
12. Stamey T.A., Yemoto C.M., McNeal J.E., et al. Prostate cancer is highly predictable: A prognostic equation based on all morphological variables in radical prostatectomy specimens. J Urol 163 (2000) 1155-1160
13. Pan C.C., Potter S.R., Partin A.W., et al. The prognostic significance of tertiary Gleason patterns of higher grade in radical prostatectomy specimens: A proposal to modify the Gleason grading system. Am J Surg Pathol 24 (2000) 563-569
14. Egevad L., Granfors T., Karlberg L., et al. Percent Gleason grade 4/5 as prognostic factor in prostate cancer diagnosed at transurethral resection. J Urol 168 (2002) 509-513
15. Rubin M.A., Mucci N.R., Manley S., et al. Predictors of Gleason pattern 4/5 prostate cancer on prostatectomy specimens: Can high grade tumor be predicted preoperatively?. J Urol 165 (2001) 114-118
16. American Joint Committee on Cancer. Prostate. In: Greene F.L., Page D.L., Fleming I.D., et al. (Eds). AJCC cancer staging manual (2002), Springer, New York 337-345
17. Lilleby W., Torlakovic G., Torlakovic E., et al. Prognostic significance of histologic grading in patients with prostate carcinoma who are assessed by the Gleason and World Health Organization grading systems in needle biopsies obtained prior to radiotherapy. Cancer 92 (2001) 311-319
18. Horwitz E.M., Hanlon A.L., Pinover W.H., et al. Defining the optimal radiation dose with three-dimensional conformal radiation therapy for patients with nonmetastatic prostate carcinoma by using recursive partitioning techniques. Cancer 92 (2001) 1281-1287
19. Buyyounouski M.K., Horwitz E.M., Hanlon A.L., et al. Positive prostate biopsy laterality and implications for staging. Urology 62 (2003) 298-303
20. Monti A.F., Ostinelli A., Frigerio M., et al. An ICRU 50 radiotherapy treatment chart. Radiother Oncol 35 (1995) 145-150
21. Cox G., and Kaplan R.S. American Society for Therapeutic Radiology and Oncology Consensus Panel. Consensus statement: Guidelines for PSA following radiation therapy. Int J Radiat Oncol Biol Phys 37 (1997) 1035-1041
22. Cox D.R. Regression models and life tables. J Royal Stat Soc 34 (1972) 187-220
23. Ciampi A.T.J., Nakache J.P., and Asselain B. Stratification by stepwise regression, correspondence analysis and recursive partition. Comput Stat Data Analysis 4 (1986) 185-204
24. Segal M.R. Regression trees for censored data. Biometrics 44 (1988) 35-47
25. Zhang H.P., and Singer B. Recursive partitioning in the health sciences (1999), Springer-Verlag, New York
26. Chism D.B., Hanlon A.L., Horwitz E.M., et al. A comparison of the single and double factor high-risk models for risk assignment of prostate cancer treated with 3D conformal radiotherapy. Int J Radiat Oncol Biol Phys 59 (2004) 380-385