Characterization of Urban Atmospheres during Inhalation Exposure Studies in Detroit and Grand Rapids, Michigan

Toxicologic Pathology

Volumn 35, Issue 1, 2007, Pages 15-22

  Keeler, Gerald J ^a   Morishita, Masako ^a   Wagner, James G ^b   Harkema, Jack R ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

CAPs (concentrated ambient particulates); complex mixtures; inhalation exposure

Indexed keywords

ALLERGEN; OVALBUMIN;

AIR POLLUTANT; ALLERGIC REACTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATMOSPHERE; CONTROLLED STUDY; EXPOSURE; HEALTH; HEALTH HAZARD; LUNG; MALE; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; RAT; UNITED STATES; URBAN AREA;

AIR POLLUTANTS; ANIMALS; CITIES; COMPLEX MIXTURES; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; ENVIRONMENTAL MONITORING; INHALATION EXPOSURE; LUNG; MALE; MICHIGAN; OVALBUMIN; PARTICLE SIZE; RATS; RATS, INBRED BN; RESPIRATORY HYPERSENSITIVITY; URBAN HEALTH;

RATTUS;

EID: 33847297495     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230601132022     Document Type: Article

References (26)

1. Carter JD Ghio AJ Samet JM Devlin RB Cytokine production by human airway epithelial cells after an exposure to an air pollution particle is metal dependent Toxicol Appl Pharmacol 1997 146 180 8
2. Clarke RW Coull B Catalano P Killingsworth CR Koutrakis P Kavouras I Krishna Murthy GG Lawrence J Lovett E Wolfson JM Verrier RL Godleski JJ Inhaled concentrated ambient particles are associated with hematologic and broinchoalveolar lavage changes in canines Environ Health Perspect 2000 108 1179 87
3. Daigle CC Chalupa DC Gibb FR Morrow PE Oberdörster G Utell MJ Frampton MW Ultrafine particle deposition in humans during rest and exercise Inhal Toxicol 2003 15 539 552
4. Fernandez A Wendt JOL Wolski N Hein KRG Wang S Witten ML Inhalation health effects of fine particles from the co-combustion of coal and refuse derived fuel Chemosphere 2003 51 1129 37
5. Gavett SH Haykal-Coates N Copeland LB Heinrich J Gilmour MI Metal composition of ambient PM2.5 influences severity of allergic airways disease in mice Environ Health Perspect 2003 12 1471 7
6. Godleski JJ Verrier RL Koutrakis P Catalano P Coull B Reinisch U Lovett EG Lawrence J Murthy GGK Wolfson JM Clarke RW Nearing BD Killingsworth C Mechanisms of morbidity and mortality from exposure to ambient air particles Res Rep Health Eff Inst 2000 91 5 103
7. Harkema J Keeler G Wagner J Morishita M Timm E Hotchkiss J Marsik FD vonch T Kaminski N Barr E HEI Research Report. Effects of inhaled urban air particulates on normal and hypersecretory airways in rats 2004 Cambridge, MA Health Effects Institute
8. Hopke PK Receptor Modeling for Air Quality Management 1991 Amsterdam Elsevier
9. Keeler GJ Spengler JD Castillo R Acid aerosol measurements at a suburban Connecticut site Atmos Environ 1991 24A 2915 23
10. Keeler GJ Dvonch JT Yip FY Parker EA Israel BA Marsik FJ Morishita M Barres JA Robins TG Brakefield-Caldwell W Sam M Assessment of personal and community-level exposures to particulate matter among children with asthma in Detroit, Michigan, as part of community action against asthma (CAAA) Environ Health Perspect 2002 110 suppl 2 173 81
11. Kim E Larson TV Hopke PK Slaughter C Sheppard LE Claiborn C Source identification of PM2.5 in an arid Northwest U.S. City by positive matrix factorization Atmos Res 2001 66 291 305
12. Lawrence J Wolfson JM Ferguson S Koutrakis P Godleski J Performance stability of the Harvard ambient particle concentrator Aero Sci Technol 2004 38 219 27
13. Li N Sioutas C Cho A Schmitz D Misra C Wang M Oberley T Froines JR Nel A Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage Environ Health Perspect 2003 111 455 60
14. Morishita M Keeler GJ Wagner JG Marsik FJ Timm EJ Dvonch TJ Harkema JR Pulmonary retention of particulate matter is associated with airway inflammation in allergic rats exposed to air pollution in Urban Detroit Inhal Toxicol 2004 16 663 74
15. Morishita M Keeler GJ Wagner JG Harkema JR Source identification of ambient PM2.5 during summer inhalation exposure studies in Detroit, MI Atmos Environ 2006 40 3835 44
16. Oberdorster G Gelein R Ferin J Weiss B Association of particulate air pollution and acute mortality: involvement of ultrafine particles Inhal Toxicol 1995 7 111 24
17. Paatero P Tapper U Positive matrix factorization: a nonnegative factor model with optimal utilization of error estimates of data values Environmetrics 1994 5 111 26
18. Peters A Dockery DW Heinrich J Wichmann HE Short-term effects of particulate air pollution on respiratory morbidity in asthmatic children Eur Respir J 1997 10 872 9
19. Riley MR Boesewetter DE Kim AM Sirvent FP Effects of metals Cu, Fe, Ni, V, and Zn on rat lung epithelial cells Toxicology 2003 190 171 84
20. Saldiva Paulo HN Clarke RW Coull BA Stearns RC Lawrence J Murthy GG Krishna Diaz E Koutrakis P Suh H Tsuda A Godleski JJ Lung inflammation induced by concentrated ambient air particles is related to particle composition Am J Respir Crit Care Med 2002 165 1610 7
21. Sioutas C Koutrakis P Goldeski JJ Ferguson ST Chong SK Burton RM Fine particle concentrators for inhalation exposures-effect of particle size and composition J Aerosol Sci 1997 28 1057 71
22. Spurny KR On the physics, chemistry and toxicology of ultrafine anthropogenic atmospheric aerosols (UAAA): new advances Toxicol Lett 1998 96–7 253 261
23. USEPA AirDATA. Office of Air and Radiation. NET Database Facility Locator Map 1999a Washington, DC USEPA
24. USEPA EPA-Code of Federal Regulations 1999b Washington, DC USEPA
25. Wagner JG Hotchkiss JA Harkema JR Enhancement of nasal inflammatory and epithelial responses after ozone and allergen co-exposure in Brown Norway rats Toxicol Sci 2002 67 284 94
26. Wagner JG Morishita M Keeler GJ Harkema JR Using a mobile particle concentrator to assess the effects of local versus transported fine particulate matter Toxicologist 2006 90 A2213