Plant progesterone 5β-reductase is not homologous to the animal enzyme. Molecular evolutionary characterization of P5βR from Digitalis purpurea

Phytochemistry

Volumn 68, Issue 6, 2007, Pages 853-864

  Gavidia, Isabel ^a   Tarrío, Rosa ^b   Rodríguez Trelles, Francisco ^b   Pérez Bermúdez, Pedro ^a   Ulrich Seitz, H ^c  

^a UNIVERSITY OF VALENCIA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Analogous enzymes; Cardenolide biosynthesis; Digitalis purpurea; Gene expression; Molecular evolution; P5 R; Plantaginaceae; SDR family; Steroid metabolism

Indexed keywords

ANIMALIA; BACTERIA (MICROORGANISMS); DIGITALIS (GENUS); DIGITALIS PURPUREA; MAMMALIA; PLANTAGINACEAE;

3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE; COMPLEMENTARY DNA; DIGITALIS; HYBRID PROTEIN; PROGESTERONE; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENETICS; ISOLATION AND PURIFICATION; MASS FRAGMENTOGRAPHY; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DIGITALIS; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EVOLUTION, MOLECULAR; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION PROFILING; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PHYLOGENY; PLANT PROTEINS; PROGESTERONE; PROGESTERONE REDUCTASE; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 33847292886     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2006.11.019     Document Type: Article

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