-
1
-
-
5644276382
-
Improving patient care through molecular diagnostics
-
Perez E.A., Pusztai L., and Van de Vijver M. Improving patient care through molecular diagnostics. Semin Oncol 31 (2004) 14-20
-
(2004)
Semin Oncol
, vol.31
, pp. 14-20
-
-
Perez, E.A.1
Pusztai, L.2
Van de Vijver, M.3
-
2
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T., Perou C.M., Tibshirani R., et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. PNAS 98 (2001) 10869-10874
-
(2001)
PNAS
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
3
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
Sotiriou C., Neo S.Y., McShane L.M., et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 100 (2003) 10393-10398
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
-
4
-
-
23844549918
-
Breast cancer molecular subtypes respond differently to preoperative chemotherapy
-
Rouzier R., Perou C.M., Symmans W.F., et al. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res 11 16 (2005) 5678-5685
-
(2005)
Clin Cancer Res
, vol.11
, Issue.16
, pp. 5678-5685
-
-
Rouzier, R.1
Perou, C.M.2
Symmans, W.F.3
-
5
-
-
0034924722
-
Randomized controlled trial of ovarian function suppression plus tamoxifen versus the same endocrine therapy plus chemotherapy: is chemotherapy necessary for premenopausal women with node-positive breast cancer? First results of International Breast Cancer Study Group trial 11-93
-
International Breast Cancer Study Group
-
International Breast Cancer Study Group. Randomized controlled trial of ovarian function suppression plus tamoxifen versus the same endocrine therapy plus chemotherapy: is chemotherapy necessary for premenopausal women with node-positive breast cancer? First results of International Breast Cancer Study Group trial 11-93. Breast 10 Suppl. 3 (2001) 130-138
-
(2001)
Breast
, vol.10
, Issue.SUPPL. 3
, pp. 130-138
-
-
-
6
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
-
Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. The Lancet 365 (2005) 1687-1717
-
(2005)
The Lancet
, vol.365
, pp. 1687-1717
-
-
-
7
-
-
0030979449
-
Randomized trial of cyclophosphamide, methotrexate and fluorouracil chemotherapy added to tamoxifen as adjuvant therapy in postmenopausal women with node-positive estrogen and/or progesterone receptor-positive breast cancer: a report of the National Cancer Institute of Canada Clinical Trials Group
-
Pritchard K.I., Paterson A.H.G., Fine S., et al. Randomized trial of cyclophosphamide, methotrexate and fluorouracil chemotherapy added to tamoxifen as adjuvant therapy in postmenopausal women with node-positive estrogen and/or progesterone receptor-positive breast cancer: a report of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 15 (1997) 2302-2311
-
(1997)
J Clin Oncol
, vol.15
, pp. 2302-2311
-
-
Pritchard, K.I.1
Paterson, A.H.G.2
Fine, S.3
-
8
-
-
0030693661
-
Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer
-
Fisher B., Dignam J., Wolmark N., et al. Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer. J Natl Cancer Inst 89 (1997) 1673-1682
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1673-1682
-
-
Fisher, B.1
Dignam, J.2
Wolmark, N.3
-
9
-
-
4544329012
-
Findings from two decades of National Surgical Adjuvant Breast and Bowel Project clinical trials involving breast cancer patients with negative axillary nodes
-
Fisher B., Jeong J.H., Bryant J., et al. Findings from two decades of National Surgical Adjuvant Breast and Bowel Project clinical trials involving breast cancer patients with negative axillary nodes. Lancet 364 (2004) 858-868
-
(2004)
Lancet
, vol.364
, pp. 858-868
-
-
Fisher, B.1
Jeong, J.H.2
Bryant, J.3
-
10
-
-
0037125429
-
Endocrine responsiveness and tailoring adjuvant therapy for postmenopausal lymph node-negative breast cancer: a randomized trial
-
International Breast Cancer Study Group
-
International Breast Cancer Study Group. Endocrine responsiveness and tailoring adjuvant therapy for postmenopausal lymph node-negative breast cancer: a randomized trial. J Natl Cancer Inst 94 (2002) 1054-1065
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1054-1065
-
-
-
11
-
-
20044365994
-
Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor
-
International Breast Cancer Study Group (IBCSG)
-
International Breast Cancer Study Group (IBCSG). Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor. Ann Oncol 16 5 (2005) 716-725
-
(2005)
Ann Oncol
, vol.16
, Issue.5
, pp. 716-725
-
-
-
12
-
-
17144369986
-
Concurrent (CAFT) versus sequential (CAF-T) chemohormonal therapy (cyclophosphamide, doxorubicin, 5-fluorouracil, tamoxifen) versus T alone for postmenopausal, node-positive estrogen (ER) and/or progesterone (PgR) receptor-positive breast cancer: mature outcomes and new biologic correlates on pahse III intergroup trial 0100 (SWOG-8814)
-
[Abstract 37]
-
Albain K., Barlow W., O'Malley F., et al. Concurrent (CAFT) versus sequential (CAF-T) chemohormonal therapy (cyclophosphamide, doxorubicin, 5-fluorouracil, tamoxifen) versus T alone for postmenopausal, node-positive estrogen (ER) and/or progesterone (PgR) receptor-positive breast cancer: mature outcomes and new biologic correlates on pahse III intergroup trial 0100 (SWOG-8814). Breast Cancer Res Treat 88 (2004) S1 [Abstract 37]
-
(2004)
Breast Cancer Res Treat
, vol.88
-
-
Albain, K.1
Barlow, W.2
O'Malley, F.3
-
13
-
-
0035806484
-
-
National Institutes of Health Consensus Development Panel: Adjuvant Therapy for Breast Cancer. J Natl Cancer Inst 2001;93:979-89.
-
-
-
-
14
-
-
27244436804
-
Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005 meeting highlights: international consensus panel on the treatment of primary breast cancer
-
Goldhirsch A., Glick J.H., Gelber R.D., et al. Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005 meeting highlights: international consensus panel on the treatment of primary breast cancer. Ann Onc 16 (2005) 1569-1583
-
(2005)
Ann Onc
, vol.16
, pp. 1569-1583
-
-
Goldhirsch, A.1
Glick, J.H.2
Gelber, R.D.3
-
15
-
-
0018191112
-
The relation between estrogen receptors and response rate to cytotoxic chemotherapy in metastatic breast cancer
-
Lippman M.E., Allegra J.C., Thompson E.B., et al. The relation between estrogen receptors and response rate to cytotoxic chemotherapy in metastatic breast cancer. New Engl J Med 298 (1978) 1223-1228
-
(1978)
New Engl J Med
, vol.298
, pp. 1223-1228
-
-
Lippman, M.E.1
Allegra, J.C.2
Thompson, E.B.3
-
16
-
-
33847291540
-
-
Harbeck N, Bohlmann I, Ross JS. Multicenter study validates PITX2 DNA methylation for risk prediction in tamoxifen-treated, node-negative breast cancer using paraffin-embedded tumor tissue. Proc Am Soc Clin Oncol 2005 [abstract 505].
-
-
-
-
17
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
Paik S., Shak S., Tang G., et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351 27 (2004) 2817-2826
-
(2004)
N Engl J Med
, vol.351
, Issue.27
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
-
18
-
-
14844341891
-
Expression of the 21 genes in the Recurrence Score assay and prediction of clinical benefit from tamoxifen in NSABP study B-14 and chemotherapy in NSABP study B-20
-
Paik S., Shak S., Tang G., et al. Expression of the 21 genes in the Recurrence Score assay and prediction of clinical benefit from tamoxifen in NSABP study B-14 and chemotherapy in NSABP study B-20. Breast Cancer Res Treat 83 (2004) A24
-
(2004)
Breast Cancer Res Treat
, vol.83
-
-
Paik, S.1
Shak, S.2
Tang, G.3
-
19
-
-
0028875410
-
Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy
-
Bergh J., Torbjorn N., Sigrid S., et al. Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy. Nat Med 1 (1995) 1029-1034
-
(1995)
Nat Med
, vol.1
, pp. 1029-1034
-
-
Bergh, J.1
Torbjorn, N.2
Sigrid, S.3
-
20
-
-
0030058617
-
The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry
-
Sjogren S., Inganas M., Norberg T., et al. The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry. J Natl Cancer Inst 88 (1996) 173-182
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 173-182
-
-
Sjogren, S.1
Inganas, M.2
Norberg, T.3
-
21
-
-
0343517136
-
Predictive Value of p53, mdm-2, p21, and mib-1 for Chemotherapy Response in Advanced Breast Cancer
-
Sjöström J., Blomqvist C., Heikkilä P., et al. Predictive Value of p53, mdm-2, p21, and mib-1 for Chemotherapy Response in Advanced Breast Cancer. Clin Cancer Res 6 (2000) 3103-3110
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3103-3110
-
-
Sjöström, J.1
Blomqvist, C.2
Heikkilä, P.3
-
22
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe S.W., Ruley H.E., Jacks T., and Housman D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74 6 (1993) 957-967
-
(1993)
Cell
, vol.74
, Issue.6
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
23
-
-
0031927983
-
Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate and fluorouracil in premenopausal women with node-positive breast cancer
-
National Cancer Institute of Canada Clinical Trials Group
-
Levine M.N., Bramwell V.H., Pritchard K.I., et al., National Cancer Institute of Canada Clinical Trials Group. Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate and fluorouracil in premenopausal women with node-positive breast cancer. J Clin Oncol 16 (1998) 2651-2658
-
(1998)
J Clin Oncol
, vol.16
, pp. 2651-2658
-
-
Levine, M.N.1
Bramwell, V.H.2
Pritchard, K.I.3
-
24
-
-
0141475108
-
NEAT (National Epirubicin Adjuvant Trial), and SCTBG BR9601 (Scottish Cancer Trials Breast Group) Phase III adjuvant breast trials show a significant relapse-free and overall survival advantage for sequential ECMF
-
[abstract 13]
-
Poole C.J., Earl H.M., Dunn J.A., et al. NEAT (National Epirubicin Adjuvant Trial), and SCTBG BR9601 (Scottish Cancer Trials Breast Group) Phase III adjuvant breast trials show a significant relapse-free and overall survival advantage for sequential ECMF. Proc Am Soc Clin Oncol 22 4 (2003) [abstract 13]
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, Issue.4
-
-
Poole, C.J.1
Earl, H.M.2
Dunn, J.A.3
-
25
-
-
0030865104
-
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute Anticancer Drug Screen and correlations with the growth-inhibitory potency of 123 anticancer agents
-
O'Connor P.M., Jackman J., Bae I., et al. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute Anticancer Drug Screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res 57 (1997) 4285-4300
-
(1997)
Cancer Res
, vol.57
, pp. 4285-4300
-
-
O'Connor, P.M.1
Jackman, J.2
Bae, I.3
-
26
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
Brown J.M., and Wouters B.G. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 59 (1999) 1391-1399
-
(1999)
Cancer Res
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
27
-
-
0035868668
-
2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology
-
Bast R.C., Ravdin P., Hayes D.F., et al. 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19 (2001) 1865-1878
-
(2001)
J Clin Oncol
, vol.19
, pp. 1865-1878
-
-
Bast, R.C.1
Ravdin, P.2
Hayes, D.F.3
-
28
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon D.J., Leyland-Jones B., Shak S., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. New Engl J Med 344 (2001) 783-792
-
(2001)
New Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
29
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond E.H., Perez E.A., Bryant J., et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 53 16 (2005) 1673-1684
-
(2005)
N Engl J Med
, vol.53
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
30
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart M.J., Procter M., Leyland-Jones B., et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 53 16 (2005) 1659-1672
-
(2005)
N Engl J Med
, vol.53
, Issue.16
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
31
-
-
33344478381
-
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
-
Joensuu H., Kellokumpu-Lehtinen P.L., Bono P., et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 354 8 (2006) 809-820
-
(2006)
N Engl J Med
, vol.354
, Issue.8
, pp. 809-820
-
-
Joensuu, H.1
Kellokumpu-Lehtinen, P.L.2
Bono, P.3
-
32
-
-
0012643984
-
Phase III comparative study of trastuzumab and paclitaxel with and without carboplatin in patients with HER-2/neu positive advanced breast cancer
-
[abstract 35]
-
Robert N., Leyland-Jones B., Asmar L., et al. Phase III comparative study of trastuzumab and paclitaxel with and without carboplatin in patients with HER-2/neu positive advanced breast cancer. Breast Cancer Res Treat 76 (2002) S37 [abstract 35]
-
(2002)
Breast Cancer Res Treat
, vol.76
-
-
Robert, N.1
Leyland-Jones, B.2
Asmar, L.3
-
33
-
-
33645720799
-
®TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2 positive early breast cancer patients: BCIRG 006 study
-
[abstract 1]
-
®TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2 positive early breast cancer patients: BCIRG 006 study. Breast Cancer Res Treat 94 (2005) S5 [abstract 1]
-
(2005)
Breast Cancer Res Treat
, vol.94
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
34
-
-
0028985716
-
Topoisomerases II alpha and beta as therapy targets in breast cancer
-
Isaacs R.J., Davies S.L., Wells N.J., et al. Topoisomerases II alpha and beta as therapy targets in breast cancer. Anticancer drugs 6 2 (1995) 195-211
-
(1995)
Anticancer drugs
, vol.6
, Issue.2
, pp. 195-211
-
-
Isaacs, R.J.1
Davies, S.L.2
Wells, N.J.3
-
35
-
-
0043145754
-
Characterization of topoisomerase IIa gene amplification and deletion in breast cancer
-
Jarvinen T.A.H., Tanner M., Barlund M., et al. Characterization of topoisomerase IIa gene amplification and deletion in breast cancer. Genes Chromosomes Cancer 26 (1999) 142-150
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 142-150
-
-
Jarvinen, T.A.H.1
Tanner, M.2
Barlund, M.3
-
36
-
-
0033870292
-
Amplification and deletion of topoisomerase IIa associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Jarvinen T.A.H., Tanner M., Rantanen V., et al. Amplification and deletion of topoisomerase IIa associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol 156 (2000) 839-847
-
(2000)
Am J Pathol
, vol.156
, pp. 839-847
-
-
Jarvinen, T.A.H.1
Tanner, M.2
Rantanen, V.3
-
37
-
-
0001887732
-
Amplification of topoisomerase IIa is a strong predictor of response to epirubicin-based chemotherapy in HER-2/neu positive metastatic breast cancer
-
[abstract 21]
-
Isola J., Tanner M., Holli K., et al. Amplification of topoisomerase IIa is a strong predictor of response to epirubicin-based chemotherapy in HER-2/neu positive metastatic breast cancer. Breast Cancer Res Treat 68 (2000) 31 [abstract 21]
-
(2000)
Breast Cancer Res Treat
, vol.68
, pp. 31
-
-
Isola, J.1
Tanner, M.2
Holli, K.3
-
38
-
-
0036091354
-
HER-2 amplification and topoisomerase IIa gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with CMF
-
Di Leo A., Gancberg D., Larsimont D., et al. HER-2 amplification and topoisomerase IIa gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with CMF. Clin Cancer Res 8 (2002) 1107-1116
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
-
39
-
-
2542644284
-
Topoisomerase II alpha (TOP2A) alterations as a predictive marker for epirubicin sensitivity in 805 high-risk breast cancer patients. A randomised DBCG trial (DBCG89D)
-
[abstract 674]
-
Knoop A., Knudsen H., Balslev E., et al. Topoisomerase II alpha (TOP2A) alterations as a predictive marker for epirubicin sensitivity in 805 high-risk breast cancer patients. A randomised DBCG trial (DBCG89D). Eur J Cancer 1 (2003) S202 [abstract 674]
-
(2003)
Eur J Cancer
, vol.1
-
-
Knoop, A.1
Knudsen, H.2
Balslev, E.3
-
40
-
-
0041301731
-
Emerging science: prospective validation of gene expression profiling-based prediction of complete pathologic response to neoadjuvant paclitaxel/FAC chemotherapy in breast cancer
-
[abstract 1]
-
Pusztai L., Ayers M., Simmans F.W., et al. Emerging science: prospective validation of gene expression profiling-based prediction of complete pathologic response to neoadjuvant paclitaxel/FAC chemotherapy in breast cancer. J Clin Oncol (2003) 237s [abstract 1]
-
(2003)
J Clin Oncol
-
-
Pusztai, L.1
Ayers, M.2
Simmans, F.W.3
-
41
-
-
0042125511
-
Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
-
Chang J.C., Wooten E.C., Tsimelzon A., et al. Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. The Lancet 362 (2003) 362-369
-
(2003)
The Lancet
, vol.362
, pp. 362-369
-
-
Chang, J.C.1
Wooten, E.C.2
Tsimelzon, A.3
-
42
-
-
20644447122
-
Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer
-
Hannemann J., Oosterkamp H.M., Bosch C.A.J., et al. Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol 23 (2005) 3331-3342
-
(2005)
J Clin Oncol
, vol.23
, pp. 3331-3342
-
-
Hannemann, J.1
Oosterkamp, H.M.2
Bosch, C.A.J.3
-
43
-
-
20444388706
-
Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer
-
Rouzier R., Rajan R., Wagner P., et al. Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer. Proc Natl Acad Sci USA 102 (2005) 8315-8320
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8315-8320
-
-
Rouzier, R.1
Rajan, R.2
Wagner, P.3
|