Effect of hyperbilirubinemia on intestinal permeability in healthy term newborns

Acta Paediatrica, International Journal of Paediatrics

Volumn 96, Issue 1, 2007, Pages 73-75

  Indrio, Flavia ^a,c   Raimondi, Francesco ^b   Laforgia, Nicola ^a   Riezzo, Gieuseppe ^a   Polimeno, Lorenzo ^a   Francavilla, Ruggiero ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c POLICLINICO   (Italy)

Author keywords

Healthy term newborns; Hyperbilirubinemia; Intestinal permeability

Indexed keywords

BILIRUBIN; LACTULOSE; MANNITOL;

APGAR SCORE; ARTICLE; BILIRUBIN BLOOD LEVEL; BIRTH WEIGHT; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GESTATIONAL AGE; HUMAN; HYPERBILIRUBINEMIA; INTESTINE MUCOSA PERMEABILITY; JAUNDICE; MALE; NEWBORN; PHOTOTHERAPY; PRIORITY JOURNAL; SEX DIFFERENCE; TERM BIRTH;

FEMALE; HUMANS; HYPERBILIRUBINEMIA, NEONATAL; INFANT, NEWBORN; INTESTINES; LACTULOSE; MALE; MANNITOL; PERMEABILITY; TERM BIRTH;

EID: 33847226313     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2006.00007.x     Document Type: Article

References (21)

1. Bakken AF. Temporary intestinal lactase deficiency in light-treated jaundiced infants. Acta Pediatr Scand 1977; 66: 92-6.
2. Ebbsen F, Edelsten D, Hertel J. Gut transit time and lactose malabsorption during phototherapy. A study using lactose-free human mature milk. Acta Pediatr Scand 1980; 69: 65-8.
3. De Curtis M, Guandalini S, Fasano A, Saitta F, Ciccimarra F. Diarrhoea in jaundiced neonates treated with phototherapy: role in intestinal secretion. Arch Dis Child 1989; 64: 1161-4.
4. Guandalini S, Fasano A, Albini F, Marchesano G, Nocerino A, De Curtis M, Rubaltelli FF, Pettenazzo A, Rubino A. Unconjugated bilirubin and the bile from light exposed Gunn rats inhibit intestinal water and electrolyte absorption. Gut 1988; 29: 366-71.
5. Raimondi F, Santoro P, Maiuri L, Londei M, Annunziata S, Ciccimarra F, Rubino A. Reactive nitrogen species modulate the effects of rhein, an active component of senna laxatives, on human epithelium in vitro. J Pediatr Gastroenterol Nutr 2002; 34: 529-34.
6. Catassi C, Bonucci A, Coppa GV, Carlucci A, Giorgi PL. Intestinal permeability changes during the first month: effect of natural versus artificial feeding. J Pediatr Gastroenterol Nutr 1995; 21: 383-6.
7. American Academy of Pediatric. Subcommittee on Hyperbilirubinemia Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation. Pediatrics 2004; 114: 297-316.
8. Generoso M De Rosa M, De Rosa R, et al. Cellobiose and lactulose coupled with mannitol and determined using ion-exchange chromatography with pulsed amperometric detection, are reliable probes for investigation of intestinal permeability. J. Chromatogr B Analyt Technol Biomed Life Sci 2003; 783: 349-57.
9. DeMeo MT, Mutlu EA, Keshavarzian A, Tobin MC. Intestinal permeation and gastrointestinal disease. J Clin Gastroenterol 2002; 34: 385-96.
10. Kalach N, Rocchiccioli F, de Boissieu D, Benhamou PH, Dupont C. Intestinal permeability in children: variation with age and reliability in the diagnosis of cow's milk allergy. Acta Paediatr 2001; 90: 499-504.
11. Sigalet DL, Martin GR, Pople A. Differential sugar absorption as a marker for adaptation in short bowel syndrome. J Pediatr Surg 2000; 35: 661-4.
12. van Elburg RM, Uil JJ, de Monchy JG, Heymans HS. Intestinal permeability in pediatric gastroenterology. Scand J Gastroenterol Suppl 1992; 194: 19-24.
13. Castellaneta SP, Masciale A, Zaccaro A, Straziuso J, Miniello V, Gatti F, et al.. Intestinal permeability in healthy breast-fed infants, during the postnatal period. JPGN 2005; 40(suppl. 2) 632.
14. Van Elburg RM, Wetter WPF, Bunkers CM, Heymans HSA. Intestinal permeability in relation to birth weight and gestational and postnatal age. Arch Dis Child Fetal Neonatal Ed 2003; 88: F52-5.
15. Ostrow JD, Pascolo L, Brites D, Tiribelli C. Molecular basis of bilirubin-induced neurotoxicity. Trends Mol Med 2004; 10: 65-70.
16. Seubert JM, Darmon AJ, El-Kadi AO, D'Souza SJ, Bend JR. Apoptosis in murine hepatoma hepa 1c1c7 wild-type, C12, and C4 cells mediated by bilirubin. Mol Pharmacol 2002; 2: 257-64.
17. Brito MA, Silva RF, Brites D. Bilirubin induces loss of membrane lipids and exposure of phosphatidylserine in human erythrocytes. Cell Biol Toxicol 2002; 18: 181-92.
18. Keshavan P, Schwemberger SJ, Smith DL, Babcock GF, Zucker SD. Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization. Int J Cancer 2004; 112: 433-45.
19. Rodrigues CM, Sola S, Brites D. Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons. Hepatology 2002; 35: 1186-95.
20. Rodrigues CM, Sola S, Castro RE, Laires PA, Brites D, Moura JJ. Perturbation of membrane dynamics in nerve cells as an early event during bilirubin-induced apoptosis. J Lipid Res 2002; 436: 885-94.
21. Raimondi F, Crivaro V, Capasso L, Maiuri L, Santoro P, Tucci et al.. Unconjugated Bilirubin Barrier Function in a human-derived in vitro model. Pediatr Res 2006; 60: 30-3.