The prevalence of hypothyroidism after treatment for laryngeal and hypopharyngeal carcinomas: Are autoantibodies of influence?

Acta Oto-Laryngologica

Volumn 127, Issue 3, 2007, Pages 312-317

  Lo Galbo, Annalisa M ^a   De Bree, Remco ^a   Kuik, Dirk J ^a   Lips, Paul Th A M ^a   Von Blomberg, B Mary E ^a   Langendijk, Johannes A ^a   Leemans, C Rene ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Autoantibodies; Hypopharyngeal carcinoma; Hypothyroidism; Laryngeal carcinoma; Questionnaire; Radiotherapy; Surgery

Indexed keywords

AUTOANTIBODY; THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN;

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CLINICAL ASSESSMENT; COLD; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HIGH RISK POPULATION; HORMONE DETERMINATION; HUMAN; HYPOPHARYNX CARCINOMA; HYPOTHYROIDISM; INCIDENCE; LARYNGECTOMY; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; MULTIVARIATE ANALYSIS; OUTPATIENT DEPARTMENT; PATIENT ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; QUESTIONNAIRE; RETROSPECTIVE STUDY; RISK FACTOR; SUBTOTAL THYROIDECTOMY; SYMPTOMATOLOGY; UNIVARIATE ANALYSIS; WEIGHT GAIN;

ADULT; AGED; AGED, 80 AND OVER; AUTOANTIBODIES; COMBINED MODALITY THERAPY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; HYPOPHARYNGEAL NEOPLASMS; HYPOTHYROIDISM; LARYNGEAL NEOPLASMS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; RADIOTHERAPY, ADJUVANT; RISK FACTORS; THYROGLOBULIN; THYROIDECTOMY; THYROTROPIN;

EID: 33847224092     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.1080/00016480600818096     Document Type: Article

References (14)

1. Smolarz K, Malke G, Voth E, Scheidhauer K, Eckel HE, Jungehulsing M, et al. Hypothyroidism after therapy for larynx and pharynx carcinoma. Thyroid 2000;10:425-9.
2. Leon X, Gras JR, Perez A, Rodriguez J, de Andres L, Orus C, et al. Hypothyroidism in patients treated with total laryngectomy. A multivariate study. Eur Arch Otorhinolaryngol 2002;259:193-6.
3. Mercado G, Adelstein DJ, Saxton JP, Secic M, Larto MA, Lavertu P. Hypothyroidism: a frequent event after radiotherapy and after radiotherapy with chemotherapy for patients with head and neck carcinoma. Cancer 2001;92:2892-7.
4. Aimoni C, Scanelli G, D'Agostino L, Pastore A. Thyroid function studies in patients with cancer of the larynx: preliminary evaluation. Otolaryngol Head Neck Surg 2003;129:733-8.
5. Koc M, Unuvar N, Sen RC, Capoglu I, Sen M. A prospective evaluation of early thyroid dysfunction on completion of neck radiotherapy. Oral Oncol 2003;39:597-600.
6. Farahati J, Demidchik EP, Biko J, Reiners C. Inverse association between age at the time of radiation exposure and extent of disease in cases of radiation-induced childhood thyroid carcinoma in Belarus. Cancer 2000;88:1470-6.
7. Pacini F, Vorontsova T, Demidchik EP,Molinaro E, Agate L, Romei C, et al. Post-Chernobyl thyroid carcinoma in Belarus children and adolescents: comparison with naturally occurring thyroid carcinoma in Italy and France. J Clin Endocrinol Metab 1997;82:3563-9.
8. Colevas AD, Read R, Thornhill J, Adak S, Tishler R, Busse P, et al. Hypothyroidism incidence after multimodality treatment for stage III and IV squamous cell carcinomas of the head and neck. Int J Radiat Oncol Biol Phys 2001;51:599-604.
9. Nishiyama K, Tanaka E, Tarui Y, Miyauchi K, Okagawa K. A prospective analysis of subacute thyroid dysfunction after neck irradiation. Int J Radiat Oncol Biol Phys 1996;34:439-44.
10. Gal RL, Gal TJ, Klotch DW, Cantor AB. Risk factors associated with hypothyroidism after laryngectomy. Otolaryngol Head Neck Surg 2000;123:211-7.
11. Sinard RJ, Tobin EJ, Mazzaferri EL, Hodgson SE, Young DC, Kunz AL, et al. Hypothyroidism after treatment for nonthyroid head and neck cancer. Arch Otolaryngol Head Neck Surg 2000;126:652-7.
12. Bryhni B, Aanderud S, Sundsfjord J, Rekvig OP, Jorde R. Thyroid antibodies in northern Norway: prevalence, persistance and relevance. J Intern Med 1996;239:517-23.
13. Tell R, Lundell G, Nilsson B, Sjödin H, Lewin F, Lewensohn R. Long-term incidence of hypothyroidism after radiotherapy in patients with head-and-neck cancer. Int J Radiat Oncol Biol Phys 2004;60:395-400.
14. Sakata S, Matsuda M, Ogawa T, Takuno H, Matsui I, Sarui H, et al. Prevalence of thyroid hormone autoantibodies in healthy subjects. Clin Endocrinol 1994;41:365-70.