Clinical value of anti-Leishmania (Leishmania) chagasi IgG titers detected by flow cytometry to distinguish infected from vaccinated dogs

Veterinary Immunology and Immunopathology

Volumn 116, Issue 1-2, 2007, Pages 85-97

  Andrade, Renata Aline de ^a   Reis, Alexandre Barbosa ^b   Gontijo, Célia Maria Ferreira ^a   Braga, Lidiane Bento ^a   Rocha, Roberta Dias Rodrigues ^a   Araújo, Márcio Sobreira Silva ^a   Vianna, Leonardo Rocha ^c   Martins Filho, Olindo Assis ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Escola de Farmacia   (Brazil)

^c CPqRR FIOCRUZ/BH ^*  (Brazil)

Author keywords

Canine visceral leishmaniasis; Flow cytometry; Leishmania (L.) chagasi; Vaccine

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN FC AFPA IGG ANTIBODY; IMMUNOGLOBULIN FC AFPA IGG1 ANTIBODY; IMMUNOGLOBULIN FC AFPA IGG2 ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2; LEISHMANIA VACCINE; LEISHMUNE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DILUTION; DOG; FEMALE; FLOW CYTOMETRY; FLUORESCENCE; IMMUNOGLOBULIN BLOOD LEVEL; LEISHMANIA CHAGASI; MALE; NONHUMAN; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEROCONVERSION; VACCINATION; VISCERAL LEISHMANIASIS;

ANIMALS; DOG DISEASES; DOGS; FEMALE; FLOW CYTOMETRY; IMMUNIZATION; IMMUNOGLOBULIN G; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; MALE; PREDICTIVE VALUE OF TESTS; PROTOZOAN VACCINES; ROC CURVE; SENSITIVITY AND SPECIFICITY;

ANIMALIA; CANIS FAMILIARIS; LEISHMANIA DONOVANI CHAGASI;

EID: 33847211740     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2007.01.002     Document Type: Article

References (43)

1. Abranches P., Silva-Pereira M.C.D., Conceição-Silva F.M., Santos-Gomes G.M., and Janz J.G. Canine Leishmaniasis: pathological and ecological factors influencing transmission of infection. J. Parasitol. 77 (1991) 557-561
2. Arias J.R., Monteiro P.S., and Zicker F. The reemergence of visceral leishmaniasis in Brazil. Emerg. Infect. Dis. 2 (1996) 145-146
3. Bicalho K.A., Ribeiro M.F., and Martins-Filho O.A. Molecular fluorescent approach to assessing intraerythrocytic hemoprotozoan Babesia canis infection in dogs. Vet. Parasitol. 125 (2004) 221-235
4. Burns Jr. J.M., Shreffler W.G., Benson D.R., Ghalib H.W., Badaró R., and Reed S.G. Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 775-779
5. Cabrera G.P., Da Silva V.O., Da Costa R.T., Reis A.B., Mayrink W., Genaro O., and Palatnik-de-Sousa C.B. The fucose-mannose ligand-ELISA in the diagnosis and prognosis of canine visceral leishmaniasis in Brazil. Am. J. Trop. Med. Hyg. 61 (1999) 296-301
6. Camargo, E.P., 1964. Growth and differentiation in Trypanosoma cruzi. I. Origin of metacyclic trypanosomes in liquid media. Rev. Inst. Med. Trop. São Paulo 6, 93-100.
7. Camargo, E.P., 1966. Fluorescent antibody test for the serodiagnosis of American Trypanosomiasis: technical modification employing preserved culture forms of Trypanosoma cruzi in slide test. Rev. Inst. Méd. Trop. São Paulo 8, 227-235.
8. Cardoso L., Schallig H.D., Neto F., Kroon N., and Rodrigues M. Serological survey of Leishmania infection in dogs from the municipality of Peso da Regua (Alto Douro Portugal) using the direct agglutination test (DAT) and fast agglutination screening test (FAST). Acta Trop. 91 (2004) 95-100
9. Deplazes P., Smith N.C., Arnold P., Lutz H., and Eckert J. Specific IgG1 and IgG2 antibody responses of dogs to Leishmania infantum and other parasites. Parasite Immunol. 17 (1995) 451-458
10. Dye C., Vidor E., and Dereure J. Serological diagnosis of leishmaniasis: on detecting infection as well as disease. Epidemiol. Infect. 110 (1993) 647-656
11. Dye C. The logic of visceral leishmaniasis control. Am. J. Trop. Med. Hyg. 55 (1996) 125-130
12. Francino O., Altet L., Sanchez-Robert E., Rodriguez A., Solano-Gallego L., Alberola J., Ferrer L., Sanchez A., and Roura X. Advantages of real-time PCR assay for diagnosis and monitoring of canine leishmaniosis. Vet. Parasitol. 137 (2006) 214-221
13. Genaro O., Costa R.T., França-Silva J.C., Reis A.B., Silva J.C., Vieira E.P., Arias J.R., Monteiro P.S., Reed S.G., Mayrink W., Costa C.A., Netto E.M., and Badaró R. Evaluation of an immunochromatographic assay for the diagnosis of dogs experimentally and naturally infected with Leishmania chagasi, in Brasil. Acta Parasitol. Turcica 21 (1997) 93-193
14. Greiner M., Pfeiffer D., and Smith R.D. Principles and pratical application of the receiver-operating characteristic analysis for diagnostic tests. Prev. Vet. Med. 45 (2000) 23-41
15. Jaeschke, R., Guyatt, G.H., Sackett, D.L., 1994. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 271, 703-707.
16. Jaroszeski M.J., and Radcliff G. Fundamentals of flow cytometry. Mol. Biotechnol. 11 (1999) 37-53
17. Lira R.A., Cavalcanti M.P., Nakazawa M., Ferreira A.G., Silva E.D., Abath F.G., Alves L.C., Souza W.V., and Gomes Y.M. Canine visceral leishmaniosis: a comparative analysis of the EIE-leishmaniose-visceral-canina-Bio-Manguinhos and the IFI-leishmaniose-visceral-canina-Bio-Manguinhos kits. Vet. Parasitol. 137 (2006) 11-16
18. Martins-Filho O.A., Pereira M.E.S., Carvalho J.F., Cançado J.R., and Brener Z. Flow cytometry, a new approach to detect anti-live trypomastigote antibodies and monitor the efficacy treatment in human Chagas disease. Clin. Diagn. Lab. Immunol. 2 (1995) 569-573
19. Mancianti F., Falcone M.L., Giannelli C., and Poli A. Comparison between an enzyme-linked immunosorbent assay using a detergent-soluble Leishmania infantum antigen and indirect immunofluorescence for the diagnosis of canine leishmaniosis. Vet. Parasitol. 59 (1995) 13-21
20. Marzochi M.C., Coutinho S.G., De Souza W.J., De Toledo L.M., Grimaldi Junior G., Momen H., Pacheco R., Da S., Sabroza P.C., De Souza M.A., and Rangel Junior F.B. Canine visceral leishmaniasis in Rio de Janeiro, Brazil. Clinical, parasitological, therapeutical and epidemiological findings (1977-1983). Mem. Inst. Oswaldo Cruz. 80 (1985) 349-357
21. Mazza G., Duffus W.P., Elson C.J., Stokes C.R., Wilson A.D., and Whiting A.H. The separation and identification by monoclonal antibodies of dog IgG fractions. J. Immunol. Methods 161 (1993) 193-203
22. Mendes C.O., Paraguai de Souza E., Borja-Cabrera G.P., Mello Batista M.L., Santos M.A., Parra L.E., Menz I., and Palatnik de Souza C.B. IgG1/IgG2 antibody dichotomy in sera of vaccinated or naturally infected dogs with visceral leishmaniosis. Vaccine 21 (2003) 2589-2597
23. Mettler M., Grimm F., Capelli G., Camp H., and Deplazes P. Evaluation of enzyme-linked immunosorbent assays, an immunofluorescent-antibody test, and two rapid tests (immunochromatographic-dipstick and gel tests) for serological diagnosis of symptomatic and asymptomatic Leishmania infections in dogs. J. Clin. Microbiol. 43 (2005) 5515-5519
24. Molina R., Amela C., Nieto J., San-Andres M., Gonzalez F., Castillo J.A., Lucientes J., and Alvar J. Infectivity of dogs naturally infected with Leishmania infantum to colonized Phlebotomus perniciosus. Trans. R. Soc. Trop. Med. Hyg. 88 (1994) 491-493
25. Nolan J.P., and Mandy F. Multiplexed and microparticle-based analyses: quantitative tools for the large-scale analysis of biological systems. Cytometry A. 69 (2006) 318-325
26. Osman O.F., Kager P.A., Zijlstra E.E., El-Hassan A.M., and Oskam L. Use of PCR on lymph-node sample as test of cure of visceral leishmaniasis. Ann. Trop. Med. Parasitol. 91 (1997) 845-850
27. Palatnik-De-Sousa C.B., Dos Santos W.R., Franca-Silva J.C., Da Costa R.T., Reis A.B., Palatnik M., Mayrink W., and Genaro O. Impact of canine control on the epidemiology of canine and human visceral leishmaniasis in Brazil. Am. J. Trop. Med. Hyg. 65 (2001) 510-517
28. Pirmez C., da Silva Trajano V., Paes-Oliveira Neto M., da-Cruz A.M., Goncalves-da-Costa S.C., Catanho M., Degrave W., and Fernandes O. Use of PCR in diagnosis of human american tegumentary leishmaniasis in Rio de Janeiro. Brazil. J. Clin. Microbiol. 37 (1999) 1819-1823
29. Quinnell R.J., Courtenay O., Garcez L.M., Kaye P.M., Shaw M.A., Dye C., and Day M.J. IgG subclass responses in a longitudinal study of canine visceral leishmaniasis. Vet. Immunol. Immunopathol. 91 (2003) 161-168
30. Reale S., Maxia L., Vitale F., Glorioso N.S., Caracappa S., and Vesco G. Detection of Leishmania infantum in dogs by PCR with lymph node aspirates and blood. J. Clin. Microbiol. 37 (1999) 2931-2935
31. Rosário E.Y., Genaro O., Franc ̧a-Silva J.C., Da Costa R.T., Mayrink W., Reis A.B., and Carneiro M. Evaluation of enzyme-linked immunosorbent assay using crude Leishmania and recombinant antigens as a diagnostic marker for canine visceral leishmaniasis. Mem. Inst. Oswaldo Cruz. 100 (2005) 197-203
32. Reis A.B., Carneiro C.M., Carvalho M.G., Teixeira-Carvalho A., Giunchetti R.C., Mayrink W., Genaro O., Correa-Oliveira R., and Martins-Filho O.A. Establishment of a microplate assay for flow cytometric assessment and it is use for the evaluation of age-related phenotypic changes in canine whole blood leukocytes. Vet. Immunol. Immunopathol. 103 (2005) 173-185
33. Reis A.B., Martins-Filho O.A., Teixeira-Carvalho A., Carvalho M.G., Mayrink W., Franca-Silva J.C., Giunchetti R.C., Genaro O., and Correa-Oliveira R. Parasite density and impaired biochemical/hematological status are associated with severe clinical aspects of canine visceral leishmaniasis. Res. Vet. Sci. 81 (2006) 68-75
34. Reis A.B., Teixeira-Carvalho A., Vale A.M., Marques M.J., Giunchetti R.C., Mayrink W., Guerra L.L., Andrade R.A., Correa-Oliveira R., and Martins-Filho O.A. Isotype patterns of immunoglobulins: hallmarks for clinical status and tissue parasite density in Brazilian dogs naturally infected by Leishmania (Leishmania) chagasi. Vet. Immunol. Immunopathol. 112 (2006) 102-116
35. Rocha R.D., Gontijo C.M., Eloi-Santos S.M., Carvalho A.T., Correa-Oliveira R., and Marques M.J. Anti-live Leishmania (Viannia) braziliensis promastigote antibodies, detected by flow cytometry, to identify active infection in american cutaneous leishmaniasis. Rev Soc. Bras. Med. Trop. 35 (2002) 551-562
36. Rocha R.D., Gontijo C.M., Eloi-Santos S.M., Teixeira-Carvalho A., Correa-Oliveira R., Ferrari T.C., Marques M.J., Mayrink W., and Martins-Filho O.A. Clinical value of anti-live Leishmania (Viannia) braziliensis immunoglobulin G subclasses, detected by flow cytometry, for diagnosing active localized cutaneous leishmaniasis. Trop. Med. Int. Health 11 (2006) 156-166
37. Schnur L., and Jacobson R.L. Parasitological techniques. The Leishmaniasis in Biology and Medicine/Clinical Aspects and Control (1987), Academic press, New York
38. Silva E.S., Meide W.F., Schoone G.J., Gontijo C.M., Schallig H.D., and Brazil R.P. Diagnosis of canine leishmaniasis in the endemic area of Belo Horizonte, Minas Gerais, Brazil by parasite, antibody and DNA detection assays. Vet. Res. Commun. 30 (2006) 637-643
39. Solano-Gallego L., Moprel P., Arboix M., Alberola J., and Ferrer L. Prevalence of Leishmania infantum infection in dogs living an Area of canine leishmaniasis endemicity using PCR on several tissue and serology. J. Clin. Microbiol. 39 (2001) 560-563
40. Swets J.A. Measuring the accuracy of diagnostic systems. Science 240 (1988) 1285-1293
41. Tesh R.B. Control of zoonotic visceral leishmaniasis: is it time to change strategies?. Am. J. Trop. Med. Hyg. 52 (1995) 287-292
42. World Health Organization, 2000. Leishmania/HIV co-infection South-Western Europe 1990-1998: retrospective analysis of 965 cases. WHO/LEISH/2000, Geneva. Eletronic access: http://whqlibdoc.who.int/hq/2000/WHO_LEISH_2000.42.pdf.
43. Youden W.J. Index for rating diagnostic tests. Cancer 3 (1950) 32