Thrombotic thrombocytopenic purpura with fatal outcome in a patient with chronic hepatitis C treated with pegylated interferon-a/2b

Scandinavian Journal of Gastroenterology

Volumn 42, Issue 3, 2007, Pages 408-409

  Deutsch, Melanie ^a   Manesis, Emanuel K ^a   Hadziyannis, Emilia ^a   Vassilopoulos, Dimitrios ^a   Archimandritis, Athanasios J ^a  

^a HIPPOKRATION HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; METFORMIN; PEGINTERFERON ALPHA2B; PREDNISOLONE; RIBAVIRIN; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ADULT; ANAMNESIS; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; CASE REPORT; CLINICAL FEATURE; CRYOGLOBULINEMIA; DIABETES MELLITUS; DRUG WITHDRAWAL; FEMALE; HASHIMOTO DISEASE; HEPATITIS C; HOSPITAL ADMISSION; HUMAN; LOW DRUG DOSE; PRIORITY JOURNAL; PSORIASIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT DURATION; TREATMENT WITHDRAWAL;

ADAM PROTEINS; ANTIVIRAL AGENTS; FATAL OUTCOME; FEMALE; HEPATITIS C, CHRONIC; HUMANS; INTERFERON ALFA-2B; MIDDLE AGED; PURPURA, THROMBOTIC THROMBOCYTOPENIC;

EID: 33847206025     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520600930685     Document Type: Article

References (5)

1. Wilson LE, Widman D, Dikman SH, Gorevic PD. Autoimmune disease complicating antiviral therapy for hepatitis C virus infection. Semin Arthritis Rheum 2002;32:163-73.
2. Ramos-Casals M, Garcia-Carrasco M, Lopez-Medrano F, Trejo O, Forns X, Lopez-Guillermo A, et al. Severe autoimmune cytopenias in treatment naïve hepatitis C virus infection: clinical description of 35 cases. Medicine (Baltimore) 2003;82:87-96.
3. Iyoda K, Kato M, Nakagawa T, Kakiuchi Y, Sugiyasu Y, Fujii E, et al. Thrombotic thrombocytopenic purpura developed suddenly during interferon treatment for chronic hepatitis C. J Gastroenterol 1998;33:588-92.
4. Yagita M, Uemura M, Nakamura T, Kunitomi A, Matsumoto M, Fujimura Y. Development of ADAMTS13 inhibitor in a patient with hepatitis C virus-related liver cirrhosis causes thrombotic thrombocytopenic purpura. J Hepatol 2005;42:420-1.
5. Stribling JY, Ahmed K, Waller A, Ahmed U, Shade RR. Thrombotic thrombocytopenic purpura (TTP) associated with interferon therapy of hepatitis C [abstract]. Am J Gastroenterol 2004;99 Suppl 10:295.