Serum resistin is associated with the severity of microangiopathies in type 2 diabetes

Biochemical and Biophysical Research Communications

Volumn 355, Issue 2, 2007, Pages 342-346

  Osawa, Haruhiko ^a   Ochi, Masaaki ^a   Kato, Kenichi ^b   Yamauchi, Junko ^a   Nishida, Wataru ^a   Takata, Yasunori ^a   Kawamura, Ryoichi ^a   Onuma, Hiroshi ^a   Takasuka, Tomomi ^a   Shimizu, Ikki ^b   Fujii, Yasuhisa ^b   Ohashi, Jun ^c   Makino, Hideichi ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Ehime Prefectural Hospital   (Japan)

^c GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Diabetic microangiopathy; Nephropathy; Neuropathy; Resistin; Retinopathy; Type 2 diabetes

Indexed keywords

CREATININE; RESISTIN;

ADIPOCYTE; ADULT; AGE; AGED; ARTICLE; BODY MASS; CREATININE BLOOD LEVEL; DIABETIC MICROANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE SEVERITY; FEMALE; GENDER; HUMAN; INSULIN RESISTANCE; JAPANESE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROLIFERATIVE RETINOPATHY;

AGED; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; FEMALE; HUMANS; MALE; MIDDLE AGED; RESISTIN; SEVERITY OF ILLNESS INDEX;

RODENTIA;

EID: 33847195403     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.01.144     Document Type: Article

References (18)

1. Steppan C., and Lazar M. The current biology of resistin. J. Intern. Med. 255 (2004) 439-447
2. Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M., Patel H.R., Ahima R.S., and Lazar M.A. The hormone resistin links obesity to diabetes. Nature 409 (2001) 307-312
3. Banerjee R., Rangwala S., Shapiro J., Rich A., Rhoades B., Qi Y., Wang J., Rajala M., Pocai A., Scherer P., Steppan C., Ahima R., Obici S., Rossetti L., and Lazar M. Regulation of fasted blood glucose by resistin. Science 303 (2004) 1195-1198
4. Rangwala S., Rich A., Rhoades B., Shapiro J., Obici S., Rossetti L., and Lazar M. Abnormal glucose homeostasis due to chronic hyperresistinemia. Diabetes 53 (2004) 1937-1941
5. DeFronzo R.A., Bonadonna R.C., and Ferrannini E. Pathogenesis of NIDDM. A balanced overview. Diabetes Care 15 (1992) 318-368
6. McCarthy M.I. Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification. Hum. Mol. Genet. 13 1 (2004) R33-R41
7. Osawa H., Onuma H., Murakami A., Ochi M., Nishimiya T., Kato K., Shimizu I., Fujii Y., Ohashi J., and Makino H. Systematic search for single nucleotide polymorphisms in the resistin gene: The absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes. Diabetes 51 (2002) 863-866
8. Osawa H., Yamada K., Onuma H., Murakami A., Ochi M., Kawata H., Nishimiya T., Niiya T., Shimizu I., Nishida W., Hashiramoto M., Kanatsuka A., Fujii Y., Ohashi J., and Makino H. The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3. Am. J. Hum. Genet. 75 (2004) 678-686
9. Osawa H., Onuma H., Ochi M., Murakami A., Yamauchi J., Takasuka T., Tanabe F., Shimizu I., Kato K., Nishida W., Yamada K., Tabara Y., Yasukawa M., Fujii Y., Ohashi J., Miki T., and Makino H. Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes. Biochem. Biophys. Res. Commun. 335 (2005) 596-602
10. Mabley J.G., and Soriano F.G. Role of nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic vascular dysfunction. Curr. Vasc. Pharmacol. 3 (2005) 247-252
11. Schaffler A., Buchler C., Muller-Ladner U., Herfarth H., Ehling A., Paul G., Scholmerich J., and Zietz B. Identification of variables influencing resistin serum levels in patients with type 1 and type 2 diabetes mellitus. Horm. Metab. Res. 36 (2004) 702-707
12. Axelsson J., Bergsten A., Qureshi A.R., Heimburger O., Barany P., Lonnqvist F., Lindholm B., Nordfors L., Alvestrand A., and Stenvinkel P. Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance. Kidney Int. 69 (2006) 596-604
13. Kielstein J.T., Becker B., Graf S., Brabant G., Haller H., and Fliser D. Increased resistin blood levels are not associated with insulin resistance in patients with renal disease. Am. J. Kidney Dis. 42 (2003) 62-66
14. Burnett M.S., Devaney J.M., Adenika R.J., Lindsay R., and Howard B.V. Cross-sectional associations of resistin, coronary heart disease, and insulin resistance. J. Clin. Endocrinol. Metab. 91 (2006) 64-68
15. The expert committee on the diagnosis and classification of diabetes mellitus, Report of the expert committee on the diagnosis and classification of diabetes mellitus, Diabetes Care 26 (Suppl 1) (2003) S5--S20.
16. Kawanami D., Maemura K., Takeda N., Harada T., Nojiri T., Imai Y., Manabe I., Utsunomiya K., and Nagai R. Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions. Biochem. Biophys. Res. Commun. 314 (2004) 415-419
17. Verma S., Li S.H., Wang C.H., Fedak P.W., Li R.K., Weisel R.D., and Mickle D.A. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation 108 (2003) 736-740
18. Smith S., Bai F., Charbonneau C., Janderova L., and Argyropoulos G. A promoter genotype and oxidative stress potentially link resistin to human insulin resistance. Diabetes 52 (2003) 1611-1618