Expression of p53/hgf/c-met/STAT3 signal in fetuses with neural tube defects

Virchows Archiv

Volumn 450, Issue 2, 2007, Pages 203-210

  Trovato, Maria ^a   D'Armiento, Maria ^b   Lavra, Luca ^c   Ulivieri, Alessandra ^c   Dominici, Roberto ^d   Vitarelli, Enrica ^a   Grosso, Maddalena ^a   Vecchione, Raffaella ^b   Barresi, Gaetano ^a   Sciacchitano, Salvatore ^c,d,e  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c FATEBENEFRATELLI HOSPITAL   (Italy)

^d CNR   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

c met; Fetus; HGF; NTD; STAT3

Indexed keywords

MESSENGER RNA; PROTEIN P53; STAT3 PROTEIN;

ARTICLE; CENTRAL NERVOUS SYSTEM; FETUS; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY; LUNG; MORPHOGENESIS; NEURAL TUBE DEFECT; PLACENTA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

FEMALE; HEPATOCYTE GROWTH FACTOR; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; NEURAL TUBE DEFECTS; PREGNANCY; PROTO-ONCOGENE PROTEINS C-MET; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33847153040     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-006-0356-5     Document Type: Article

References (35)

1. Achim CL, Katyal S, Wiley CA, Shiratori M, Wang G, Oshika E, Petersen BE, Li JM, Michalopoulos GK (1997) Expression of HGF and c-met in the developing and adult brain. Dev Brain Res 102:299-303
2. Bhargava M, Joseph A, Knesel J, Halaban R, Li Y, Pang S, Goldberg I, Setter E, Donovan MA, Zarnegar R, Michalopoulos GA, Nakamura T, Faletto D, Rosen EM (1992) Scatter factor and hepatocyte growth factor: activities, properties, and mechanism. Cell Growth Differ 3:11-20
3. Birchmeier C, Sonnenberg E, Weidner KM, Walter B (1993) Tyrosine kinase receptors in the control of epithelial growth and morphogenesis during development. Bioessays 15:185-190
4. Boccaccio C, Ando M, Tamagnone L, Bardelli A, Michieli P, Battistini C, Comoglio PM (1998) Induction of epithelial tubules by growth factor HGF depends on the STAT pathway. Nature 391:285-288
5. Cohen MMJ, Lemire RJ (1992) Syndromes with cephaloceles. Teratologia 25:161-172
6. Copp AJ, Brook FA, Estibeiro JP, Shum AS, Cockroft DL (1990) The embryonic development of mammalian neural tube defects. Prog Neurobiol 35:363-403
7. DeSesso JM, Scialli AR, Holson JF (1999) Apparent lability of neural tube closure in laboratory animals and humans. Am J Med Genet 87:143-162
8. Detrait ER, George TM, Etchevers HC, Gilbert JR, Vekemans M, Speer MC (2005) Human neural tube defects: developmental biology, epidemiology, and genetics. Neurotoxicol Teratol 27:515-524
9. Di Renzo MF, Bertolotto A, Olivero M, Putzolu P, Crepaldi T, Schiffer D, Pagni CA, Comoglio PM (1993) Selective expression of the met/HGF-receptor in human central nervous system microglia. Oncogene 8:219-222
10. Gordon R (1985) A review of the theories of vertebrate neurulation and their relationship to the mechanics of neural tube birth defects. J Embryol Exp Morphol 89:229-255
11. Gos M, Szpecht-Potocka A (2002) Genetic basis of neural tube defects. I. Regulatory genes for the neurulation process. J Appl Genet 43:343-350
12. Gown AM, deWever N, Battifora H (1993) Microwaved-based antigen unmasking. A revolutionary new technique for routine immunohistochemistry. Appl Immunohistochem 1:256-266
13. Honda S, Kagoshima M, Wanaka A, Tohyama M, Matsumoto K, Nakamura T (1995) Localization and functional coupling of HGF and c-met/HGF receptor in rat brain: implication as neurotrophic factor. Brain Res Mol Brain Res 32:197-210
14. Jeffers M, Fiscella M, Webb CP, Anver M, Koochekpour S, Vande Woude GF (1998) The mutationally activated Met receptor mediates motility and metastasis. Proc Natl Acad Sci 95:14417-14422
15. Jung W, Castren E, Odenthal M, Vande Woude GF, Ishii T, Dienes HP, Lindholm D, Schirmacher P (1994) Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J Cell Biol 126:485-494
16. Kolatsi-Joannou M, Moore R, Winyard PJ, Woolf AS (1997) Expression of hepatocyte growth factor/scatter factor and its receptor, MET, suggests roles in human embryonic organogenesis. Pediatr Res 41:657-665
17. Lemire RJ (1988) Neural tube defects. JAMA 259:558-562
18. Metcalfe AM, Dixon RM, Radda GK (1997) Wild-type but not mutant p53 activates the hepatocyte growth factor/scatter factor promoter. Nucleic Acids Res 25:983-986
19. Mitchell L (2005) Epidemiology of neural tube defects. Am J Med Genet Part C 135C:88-94
20. Montesano R, Matsumoto K, Nakamura T, Orci L (1991) Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67:901-908
21. Morrissey RE, Mottet NK (1980) Neural tube defects and brain anomalies: a review of selected teratogens and their possible modes of action. Neurotoxicology 2:125-162
22. Müller F, O'Rahilly R (1987) The development of the human brain, the closure of the caudal neuropore, and the beginning of secondary neurulation at stage 12. Anat Embryol 176:413-430
23. Naldini L,Weidner KM, Vigna E, Gaudino G, Bardelli A, Ponzetto C, Narsimhan RP, Hartmann G, Zarnegar R, Michalopoulos GK, Birchmeierl W, Comoglio PM (1991) Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J 10:2867-2878
24. Ohmichi H, Koshimizu U, Matsumoto K, Nakamura T (1998) Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development. Development 125:1315-1324
25. Piscione TD, Rosenblum ND (2002) The molecular control of renal branching morphogenesis: current knowledge and emerging insights. Differentiation 70:227-246
26. Sakurai H, Barros EJ, Tsukamoto T, Barasch J, Nigam SK (1997) An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors. Proc Natl Acad Sci USA 94:6279-6284
27. Seol DW, Chen Q, Smith ML, Zarnegar R (1999) Regulation of the c-met proto-oncogene promoter by p53. J Biol Chem 274:3565-3572
28. Taijima H, Matsumoto K, Nakamura T (1992) Regulation of cell growth and motility by hepatocyte growth factor and receptor expression in various cell species. Exp Cell Res 202:423-431
29. The EUROCAT Working Group (1987) Prevalence of neural tube defects in 16 regions of Europe 1980-1983. Int J Epidemiol 16:246-251
30. Trovato M, Grosso M, Vitarelli E, Benvenga S, Trimarchi F, Barresi G (2002) Immunoexpression of the hepatocyte growth factor (HGF), HGF-receptor (c-met) and STAT3 on placental tissues from malformed fetuses. Histol Histopathol 17:691-698
31. Uehara Y, Minowa O, Mori C, Shiota K, Kuno J, Noda T, Kitamura N (1995) Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 373:702-705
32. Wang Y, Selden C, Farnaud S, Calnan D, Hodgson HJ (1994) Hepatocyte growth factor (HGF/SF) is expressed in human epithelial cells during embryonic development; studies by in situ hybridisation and Northern blot analysis. J Anat 185:543-551
33. Zarnegar R, Muga S, Rahija R, Michalopoulos G (1990) Tissue distribution of hepatopoietin A: a heparin binding polypeptide growth factor for hepetocytes. Proc Natl Acad Sci USA 87:1252-1256
34. Zarnegar R, Michalopoulos GK (1995) The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J Cell Biol 129:1177-1180
35. Zhang YW, Vande Woude GF (2003) HGF/SF-Met signaling in the control of branching morphogenesis and invasion. J Cell Bifochem 88:408-417