메뉴 건너뛰기




Volumn 13, Issue 1, 2007, Pages 82-87

Past and future use of default assumptions and uncertainty factors: Default assumptions, misunderstandings, and new concepts

Author keywords

[No Author keywords available]

Indexed keywords


EID: 33847147070     PISSN: 10807039     EISSN: 15497860     Source Type: Journal    
DOI: 10.1080/10807030601105480     Document Type: Review
Times cited : (12)

References (28)
  • 1
    • 0024202909 scopus 로고
    • Reference dose (RfD): Description and use in health risk assessments
    • Barnes DG and Dourson M. 1988. Reference dose (RfD): Description and use in health risk assessments. Regul Toxicol Pharmacol 8:471-86
    • (1988) Regul Toxicol Pharmacol , vol.8 , pp. 471-486
    • Barnes, D.G.1    Dourson, M.2
  • 2
    • 21444461627 scopus 로고
    • A toxicological basis to derive generic interspecies uncertainty factors for application in human and ecological risk assessment
    • Calabrese EJ and Baldwin LA. 1995. A toxicological basis to derive generic interspecies uncertainty factors for application in human and ecological risk assessment. Hum Ecol Risk Assess 1(5):555-64
    • (1995) Hum Ecol Risk Assess , vol.1 , Issue.5 , pp. 555-564
    • Calabrese, E.J.1    Baldwin, L.A.2
  • 3
    • 0021054771 scopus 로고
    • Regulatory history and experimental support of uncertainty (safety) factors
    • Dourson ML and Stara JF. 1983. Regulatory history and experimental support of uncertainty (safety) factors. Regul Toxicol Pharmacol 3:224-38
    • (1983) Regul Toxicol Pharmacol , vol.3 , pp. 224-238
    • Dourson, M.L.1    Stara, J.F.2
  • 4
    • 0026683128 scopus 로고
    • On reference dose (RfD) and its underlying toxicity data base
    • Dourson ML, Knauf LA, and Swartout JC. 1992. On reference dose (RfD) and its underlying toxicity data base. Toxicol Ind Health 8(3):171-89
    • (1992) Toxicol Ind Health , vol.8 , Issue.3 , pp. 171-189
    • Dourson, M.L.1    Knauf, L.A.2    Swartout, J.C.3
  • 5
    • 0029803289 scopus 로고    scopus 로고
    • Evolution of science-based uncertainty factors in noncancer risk assessment
    • Dourson ML, Felter SP and Robinson D. 1996. Evolution of science-based uncertainty factors in noncancer risk assessment. Regul Toxicol Pharmacol 24:108-20
    • (1996) Regul Toxicol Pharmacol , vol.24 , pp. 108-120
    • Dourson, M.L.1    Felter, S.P.2    Robinson, D.3
  • 6
    • 0035215180 scopus 로고    scopus 로고
    • Uncertainties in the reference dose for methylmercury
    • Dourson ML, Wullenweber AE, and Poirier KA. 2001. Uncertainties in the reference dose for methylmercury. NeuroToxicology 22(5):677-89
    • (2001) NeuroToxicology , vol.22 , Issue.5 , pp. 677-689
    • Dourson, M.L.1    Wullenweber, A.E.2    Poirier, K.A.3
  • 7
    • 0036597905 scopus 로고    scopus 로고
    • Differential sensitivity of children and adults to chemical toxicity: II. Risk and regulation
    • Dourson ML, Charnley G, and Scheuplein R. 2002. Differential sensitivity of children and adults to chemical toxicity: II. Risk and regulation. Regul Toxicol Pharmacol 35:448-67
    • (2002) Regul Toxicol Pharmacol , vol.35 , pp. 448-467
    • Dourson, M.L.1    Charnley, G.2    Scheuplein, R.3
  • 8
    • 22044438042 scopus 로고    scopus 로고
    • The inexact science of risk assessment (and implications for risk management)
    • Felter SP and Dourson ML. 1998. The inexact science of risk assessment (and implications for risk management). Hum Ecol Risk Assess 2:245-51
    • (1998) Hum Ecol Risk Assess , vol.2 , pp. 245-251
    • Felter, S.P.1    Dourson, M.L.2
  • 9
    • 0036850489 scopus 로고    scopus 로고
    • An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: Examples with warfarin and parathion
    • Gentry PR, Hack CE, Haber L, et al. 2002. An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: Examples with warfarin and parathion. Toxicol Sci 70(1):120-39
    • (2002) Toxicol Sci , vol.70 , Issue.1 , pp. 120-139
    • Gentry, P.R.1    Hack, C.E.2    Haber, L.3
  • 10
    • 25844482581 scopus 로고    scopus 로고
    • Categorical regression analysis of toxicity data
    • Haber L, Strickland JA, and Guth DJ. 2001. Categorical regression analysis of toxicity data. Comm Toxicol 7(5-6):437-52
    • (2001) Comm Toxicol , vol.7 , Issue.5-6 , pp. 437-452
    • Haber, L.1    Strickland, J.A.2    Guth, D.J.3
  • 11
    • 0023601752 scopus 로고
    • Human variability in susceptibility to toxic chemicals: A preliminary analysis of pharmacokinetic data from normal volunteers
    • Hattis D, Erdreich L, and Ballew M. 1987. Human variability in susceptibility to toxic chemicals: A preliminary analysis of pharmacokinetic data from normal volunteers. Risk Anal 7(4):415-26
    • (1987) Risk Anal , vol.7 , Issue.4 , pp. 415-426
    • Hattis, D.1    Erdreich, L.2    Ballew, M.3
  • 15
    • 0242375665 scopus 로고
    • Interspecies extrapolation based on mechanistic determinants of chemical disposition
    • Jarabek AM. 1995. Interspecies extrapolation based on mechanistic determinants of chemical disposition. Hum Ecol Risk Assess 1(5):641-62
    • (1995) Hum Ecol Risk Assess , vol.1 , Issue.5 , pp. 641-662
    • Jarabek, A.M.1
  • 16
    • 0024951765 scopus 로고
    • Inhalation reference dose (RfD): An application of interspecies dosimetry modeling for risk assessment of insoluble particles
    • Jarabek AM, Menache MG, Overton JH Jr, et al. 1989. Inhalation reference dose (RfD): An application of interspecies dosimetry modeling for risk assessment of insoluble particles. Health Phys 57(Suppl 1):177-83
    • (1989) Health Phys , vol.57 , Issue.SUPPL. 1 , pp. 177-183
    • Jarabek, A.M.1    Menache, M.G.2    Overton Jr, J.H.3
  • 17
    • 33847096063 scopus 로고    scopus 로고
    • Kalberlah F and Schneider K 1998. Quantification of Extrapolation Factors. Final report of the research project No 116 06 113. Federal Environmental Agency, Germany
    • Kalberlah F and Schneider K 1998. Quantification of Extrapolation Factors. Final report of the research project No 116 06 113. Federal Environmental Agency, Germany
  • 19
    • 0027183414 scopus 로고
    • Workshop on the scientific evaluation of the safety factor for the acceptable daily intake (ADI): Editorial summary
    • Kroes R, Munro I, and Poulsen E. 1993. Workshop on the scientific evaluation of the safety factor for the acceptable daily intake (ADI): Editorial summary. Food Addit Contam 10(3):269-273
    • (1993) Food Addit Contam , vol.10 , Issue.3 , pp. 269-273
    • Kroes, R.1    Munro, I.2    Poulsen, E.3
  • 20
    • 33847168258 scopus 로고    scopus 로고
    • McColl RS. 1990. Biological safety factors in toxicological risk assessment. Cat. H49-49/1990E. 90-EHD-154. Environmental Health Directorate, Health and Welfare Canada. Ottawa, Ontario
    • McColl RS. 1990. Biological safety factors in toxicological risk assessment. Cat. H49-49/1990E. 90-EHD-154. Environmental Health Directorate, Health and Welfare Canada. Ottawa, Ontario
  • 21
    • 0028077675 scopus 로고
    • Approach to assessment of risk to human health for priority substances under the Canadian Environmental Protection Act
    • Meek ME, Newhook R, Liteplo RG, et al. 1994. Approach to assessment of risk to human health for priority substances under the Canadian Environmental Protection Act. Environ Carcinogen Ecotoxicol Rev C12(2):105-34
    • (1994) Environ Carcinogen Ecotoxicol Rev , vol.C12 , Issue.2 , pp. 105-134
    • Meek, M.E.1    Newhook, R.2    Liteplo, R.G.3
  • 23
    • 0027171701 scopus 로고
    • Data derived safety factors for the evaluation of food additives and environmental contaminants
    • Renwick AG. 1993. Data derived safety factors for the evaluation of food additives and environmental contaminants. Food Addit Contam 10(3):275-305
    • (1993) Food Addit Contam , vol.10 , Issue.3 , pp. 275-305
    • Renwick, A.G.1
  • 24
    • 0002700442 scopus 로고
    • Harmonization of approaches to the assessment of risk from exposure to chemicals
    • Sonich-Mullin C. 1995. Harmonization of approaches to the assessment of risk from exposure to chemicals. Risk Newsletter 15(4):6-7
    • (1995) Risk Newsletter , vol.15 , Issue.4 , pp. 6-7
    • Sonich-Mullin, C.1
  • 25
    • 33847160915 scopus 로고    scopus 로고
    • USEPA (US Environmental Protection Agency). 1996. Proposed Guidelines for Carcinogen Risk Assessment. EPA/600/P-92/003C. Office of Research and Development, Washington, DC, USA. April
    • USEPA (US Environmental Protection Agency). 1996. Proposed Guidelines for Carcinogen Risk Assessment. EPA/600/P-92/003C. Office of Research and Development, Washington, DC, USA. April
  • 26
    • 0141480662 scopus 로고    scopus 로고
    • A Review of the Reference Dose and Reference Concentration Processes
    • USEPA, Available at
    • USEPA. 2002. A Review of the Reference Dose and Reference Concentration Processes. Risk Assessment Forum, Washington, DC, USA. EPA/630/P-02/002F. Available at http://cfpub.epa.gov/ncea/raf/recordisplay.cfm?deid=55365
    • (2002) Risk Assessment Forum, Washington, DC, USA. EPA/630/P-02/002F
  • 27
    • 0004104069 scopus 로고    scopus 로고
    • USEPA, National Center for Environmental Assessment, Office of Research and Development. Washington, DC, USA
    • USEPA. 2005. Integrated Risk Information System (IRIS). National Center for Environmental Assessment, Office of Research and Development. Washington, DC, USA
    • (2005) Integrated Risk Information System (IRIS)
  • 28
    • 22844456200 scopus 로고    scopus 로고
    • Replacing the default values of 10 with data-derived values: A comparison of two different data derived uncertainty factors for boron
    • Zhao Q, Unrine J, and Dourson ML. 1999. Replacing the default values of 10 with data-derived values: A comparison of two different data derived uncertainty factors for boron. Hum Ecol Risk Assess 5(5):973-83
    • (1999) Hum Ecol Risk Assess , vol.5 , Issue.5 , pp. 973-983
    • Zhao, Q.1    Unrine, J.2    Dourson, M.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.