Use of p63 for distinction of glandular versus squamos lesions in cervicovaginal specimens

Cancer

Volumn 111, Issue 1, 2007, Pages 54-57

  Garcia, Monica T ^a   Acar, B Cenk ^a   Jorda, Merce ^a   Gomez Fernandez, Carmen ^a   Ganjei Azar, Parvin ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b JACKSON MEMORIAL HOSPITAL   (United States)

Author keywords

Atypical glandular cells of uncertain significance; Cytology; High grade squamous intraepithelial lesion; Liquid based PAP test; p63 immunocytochemistry

Indexed keywords

PROTEIN P63;

ADENOCARCINOMA; ARTICLE; CANCER GRADING; DIFFERENTIAL DIAGNOSIS; ENDOMETRIAL DISEASE; FEMALE; FOLLOW UP; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE; UTERINE CERVIX; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CYTOLOGY; VAGINA;

ADENOCARCINOMA; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; NEOPLASMS, GLANDULAR AND EPITHELIAL; NEOPLASMS, SQUAMOUS CELL; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS; VAGINAL NEOPLASMS;

EID: 33847141773     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22419     Document Type: Article

References (15)

1. Wang BY, Gil J, Kaufman D, Gan L, Kohtz DS, Burstein DE. p63 in pulmonary epithelium pulmonary squamous neoplasm and other pulmonary tumors. Human Pathol. 2002;33:921-926.
2. Takeuchi Y, Tamura A, Kamiya M, Fukuda T, Ishikawa O. Immunohistochemical analyses of p63 expression in cutaneous tumours. Br J Derm. 2005;153:1230-1232.
3. Quade BJ, Yang A, Wang Y, et al. Expression of the p53 homologue p63 in early cervical neoplasia. Gynecol Oncol. 2001;80:24-29.
4. Wang TY, Chen BF, Yang YC, et al. Histologic and Immunophenotypic classification of cervical carcinomas by expression of the p53 homologue p63: a study of 250 cases. Hum Pathol. 2001;32:479-486.
5. Comperat E, Camparo P, Haus R, et al. Immunohistochemical expression of p63, p53 and MIB-1 in urinary bladder carcinoma. A tissue microarray study of 158 cases. Virchows Arch. 2006;448:319-324.
6. Weinstein MH, Signoretti S, Loda M. Diagnostic utility of immunohistochemical staining for p63, a sensitive marker for prostatic basal cells. Mod Pathol. 2002;15:1302-1308.
7. Matos I, Dufloth R, Alvarenga M, Zeferino LC, Schmitt F. p63, cytokeratin and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas. Virchows Arch. 2005;447:688-694.
8. Maruya S, Kies MS, Williams M, et al. Differential expression of p63 isotypes (DeltaN and TA) in salivary gland neoplasms: biological and diagnostic implications. Hum Pathol. 2005;36:821-827.
9. Kawahara A, Harada H, Yokoyama T, Kage M. p63 Expression of clear myoepithelial cells in epithelial-myoepithelial carcinoma of the salivary gland: a useful marker for naked myoepithelial cells in cytology. Cancer. 2005;105:240-245.
10. Shtilbans V, Szporn AH, Wu M, Burstein DE. p63 immunostaining in destained bronchoscopic cytological specimens. Diagn Cytopathol. 2005;32:198-203.
11. Wu M, Szporn AH, Zhang D, et al. Cytopathology applications of p63 and TTF-1 immunostaining in differential diagnosis of lung cancers. Diagn Cytopathol. 2005;33:223-227.
12. Davis-Devine S, Day SJ, Freund GG. Test performance comparison of inform HPV and hybrid capture 2 high-risk HPV DNA tests using the SurePath liquid-based Pap test as the collection method. Am J Clin Pathol. 2005;124:24-30.
13. Solomon D, Davey D, Kurman R, et al. The 2001 Bethesda System: terminology for reporting results of cervical cytology. JAMA. 2002;287:2114-2119.
14. Comment in: JAMA. 2002;287:2140-2141.
15. Nadji M, Ganjei P. Immunocytochemistry in diagnostic cytology: a 12-year perspective. Am J Clin Pathol. 1990;94:470-475.