Effects of dietary L-carnitine and coenzyme Q10 at different supplemental ages on growth performance and some immune response in ascites-susceptible broilers

Archives of Animal Nutrition

Volumn 61, Issue 1, 2007, Pages 50-60

  Geng, Ailian ^a   Li, Baoming ^a   Guo, Yuming ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Broilers; Coenzyme Q10; Growth performance; Immune response; L carnitine

Indexed keywords

CARNITINE; DRUG DERIVATIVE; UBIDECARENONE; UBIQUINONE; VITAMIN B COMPLEX;

AGE; ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; ASCITES; BIRD DISEASE; CHICKEN; DIET SUPPLEMENTATION; DISEASE PREDISPOSITION; DOSE RESPONSE; DRUG POTENTIATION; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MALE; RANDOMIZATION;

AGE FACTORS; ANIMAL FEED; ANIMALS; ASCITES; CARNITINE; CHICKENS; DIETARY SUPPLEMENTS; DISEASE SUSCEPTIBILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; MALE; POULTRY DISEASES; RANDOM ALLOCATION; UBIQUINONE; VITAMIN B COMPLEX;

AVES; GLYCINE MAX; ZEA MAYS;

EID: 33847101945     PISSN: 1745039X     EISSN: 14772817     Source Type: Journal    
DOI: 10.1080/17450390601117041     Document Type: Article

References (30)

1. Arafa HMM, Abd-Allah ARA, El-Mahdy MA, Ramadan LA, Hamada FMA. 2003. Immunomodulatory effects of L-carnitine and q10 in mouse spleen exposed to low-frequency high-intensity magnetic field. Toxicology 187:171-181.
2. Bliznakov EG. 1978. Immunological senescence in mice and its reversal by coenzyme Q10. Mech Aging Dev 7:189-197.
3. Buyse J, Janssens GPJ, Decuypere E. 2001. The effects of dietary L-carnitine supplementation on the performance, organ weights and circulating hormone and metabolite concentrations of broiler chickens reared under a normal or low temperature schedule. Br Poult Sci 42:230-241.
4. Cawthon D, Beers K, Bottje WG. 2001. Electron transport chain defect and inefficient respiration may underlie pulmonary hypertension syndrome (ascites)-associated mitochondrial dysfunction in broilers. Poult Sci 80:474-484.
5. Çelik L, Öztürkcan O. 2003. Effects of dietary supplemental L-carnitine and ascorbic acid on performance, carcass composition and plasma L-carnitine concentration of broiler chicks reared under different temperature. Arch Anim Nutr 57:27-38.
6. De Simone C, Ferrari M, Lozzi A, Meli D, Ricca D, Sorice F. 1982. Vitamins and immunity: Influence of L-carnitine on the immune system. Acta Vitaminologica et Enzymologica 4:135-140.
7. Deufel T. 1990. Determination of L-carnitine in biological fluids and tissues. J Clin Chem Clin Biochem 28:307-311.
8. Dionyssopoulou E, Vassiliadis S, Evangeliou A, Koumantakis EE, Athanassakis I. 2005. Constitutive or induced elevated levels of L-carnitine correlate with the cytokine and cellular profile of endometriosis. J Reprod Immunol 65:159-170.
9. Famularo G, De Simone C. 1995. A new era for carnitine. Immuno Today 16:211-213.
10. Famularo G, De Simone C, Arrigoni-Martelli E, Jirillo E. 1995. Carnitine and septic shock patients. AIDS 6:203-205.
11. Folkers K, Wolaniuk A. 1985. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res 11:539-545.
12. Folkers K, Morita M, Mcree J Jr. 1993. The activities of coenzyme Q10 and vitamin B6 for immune responses. Biochem Biophys Res Commun 193:88-92.
13. 10 supplementation on performance and ascites mortality of broilers. Arch Anim Nutr 58:473-482.
14. 10. Poult Sci 83:1588-1594.
15. Huchzermeyer FW, De Ruyck AMC. 1986. Pulmonary hypertension syndrome associated with ascites in broilers. Vet. Record 119:94-96.
16. Jain NC. 1986. Schalm's veterinary hematology. 4th ed. Philadelphia: Lea and Febiger. pp 31-41.
17. Janssens GPJ, Mast J, Goddeeris M, Cox E, Hesta M, De Wilde ROM. 2000. Enhanced specific antibody response to bovine serum albumin in pigeons due to L-carnitine supplementation. Br Poult Sci 41:448-453.
18. Julian RJ. 1993. Ascites in poultry. Avian Pathol 22:419-454.
19. Kreukniet MB, Nieuwland GB, Van Der Zijpp AJ. 1994. Phagocytic activity of two lines of chickens divergently selected for antibody production. Vet Immunol Immunopatholo 44:377-387.
20. Majeed T, De Simone C, Famularo G, Marcellini S, Behan PO. 1995. Abnormalities of carnitine metabolism in chronic fatigue syndrome. Euro J Neurol 2:425-428.
21. Mast J, Buyse J, Goddeeris BM. 2000. Dietary L-carnitine supplementation increases antigen-specific immunoglobulin G production in broiler chickens. Br J Nutr 83:161-166.
22. Maxwell MH, Robertson GW. 1997. World broiler ascites survey. Poult Inter 36:16-30.
23. Monti D, Cossarizza A, Troiano L, Arrigoni-Martelli E, Franceschi C. 1989. Immunomodulatory properties of L-aectylcarnitine on lymphocytes from young and old humans. In: De Simone C, Arrigoni-Martelli E, editors. Stress immunity and ageing. A role for L-acetylcarnitine. Amsterdam: Elsevier. pp 83-96.
24. Nakamura K, Noguchi K, Aoyama T, Nakajlma T, Tanimura N. 1996. Protective effect of ubiquinone (coenzyme Q9) on ascites in broiler chickens. Br Poult Sci 37:189-195.
25. Rabie MH, Szilagyi M, Gippert T. 1997. Effects of dietary L-carnitine supplementation and protein level on performance and degree of meatiness and fatness of broilers. Acta Biol Hung 48:221-229.
26. Rabie MH, Szilagyi M. 1998. Effects of L-carnitine supplementation of diets differing in energy levels on performance, abdominal fat content, and yield and composition of edible meat of broilers. Br J Nutr 80:391-400.
27. Rodehutscord M, Timmler R, Dieckmann A. 2002. Effect of L-carnitine supplementation on utilization of energy and protein in broiler chicken fed different dietary fat levels. Arch Anim Nutr 56:431-441.
28. Tanner HA. 1992. Energy transformations in the biosynthesis of the immune system: their relevance to the progression and treatment of AIDS. Med Hypotheses 38:315-321.
29. Wang SP. 2001. Determination of immunoglobulins, transferrin and apolipoproteins by turbidimetric immunoassay. China Sports Med J 20:392-395 [in Chinese].
30. Wu JS, Zhang RJ, Zhou YP, Zheng SJ, Yang HC, Guo YP. 1997. Optimal conditions for the chicken lymphocyte transformation test in whole blood assays. Acta Veterinaria et Zootechnica Sinica 28:212-216 [in Chinese].