Application of drug selective electrode in the drug release study of pH-responsive microgels

Journal of Controlled Release

Volumn 118, Issue 1, 2007, Pages 87-94

  Tan, Jeremy P K ^a   Tam, Kam C ^a,b  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Drug selective electrode; Emulsion polymerization; In vitro release; MAA; pH responsive microgel

Indexed keywords

DRUG ELECTRODES; DRUG SELECTIVE ELECTRODE; IN VITRO RELEASE; METHACRYLIC ACID-ETHYL ACRYLATE (MAA-EA); PH-RESPONSIVE MICROGEL;

DIALYSIS; DIFFUSION; EMULSION POLYMERIZATION; PH EFFECTS; POLYVINYL CHLORIDES;

DRUG PRODUCTS;

ACRYLIC ACID ETHYL ESTER; CATION; METHACRYLIC ACID; METHACRYLIC ACID ETHYL ACRYLATE; PLASTICIZER; POLY(ETHYLENE CO VINYL ACETATE CO CARBON MONOXIDE); POLYMER; POLYVINYLCHLORIDE; PROCAINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SELECTIVE ELECTRODE; DRUG STABILITY; ELECTRODE; GEL; MICROGEL; PH; PRIORITY JOURNAL; REPRODUCIBILITY;

ACRYLATES; ANESTHETICS, LOCAL; HYDROGEN-ION CONCENTRATION; ION-SELECTIVE ELECTRODES; MEMBRANES, ARTIFICIAL; METHACRYLATES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PARTICLE SIZE; PLASTICIZERS; POLYVINYL CHLORIDE; PROCAINE; REPRODUCIBILITY OF RESULTS;

EID: 33847099613     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.11.017     Document Type: Article

References (20)

1. Langer R. Drug delivery: drugs on target. Science 293 (2001) 58-59
2. Mathiowitz E. Encyclopedia of Controlled Drug Delivery (1999), John Wiley and Sons
3. Lopez V.C., Hadgraft J., and Snowden M.J. The use of colloidal microgels as a transdermal drug delivery system. Int. J. Pharm. 292 (2005) 137-147
4. Pillay V., and Fassihi R. In vitro release modulation from crosslinked pellets for site-specific drug delivery to the gastrointestinal tract. I. Comparison of pH-responsive drug release and associated kinetics. J. Control. Release 59 (1999) 229-242
5. Kim B., and Peppas N.A. In vitro release behavior and stability of insulin in complexation hydrogels as oral drug delivery carriers. Int. J. Pharm. 266 (2003) 29-37
6. Kurkuri M.D., and Aminabhavi T.M. Poly(vinyl alcohol) and poly(acrylic acid) sequential interpenetrating network pH-sensitive microspheres for the delivery of diclofenac sodium to the intestine. J. Control. Release 96 (2004) 9-20
7. Sutani K., Kaetsu I., Uchida K., and Matsubara Y. Stimulus responsive drug release from polymer gel. Controlled release of ionic drug from polyampholyte gel. Radiat. Phys. Chem. 64 (2002) 331-336
8. Soppimath K.S., Kulkarni A.R., and Aminabhavi T.M. Chemically modified polyacrylamide-g-guar gum-based crosslinked anionic microgels as pH-sensitive drug delivery systems: preparation and characterization. J. Control. Release 75 (2001) 331-345
9. Yang M., Cui F., You B., Wang L., Yue P., and Kawashima Y. A novel pH-dependent gradient-release delivery system for nitrendipine. II. Investigations of the factors affecting the release behaviors of the system. Int. J. Pharm. 286 (2004) 99-109
10. Govender T., Stolnik S., Garnett M.C., Illum L., and Davis S.S. PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J. Control. Release 57 (1999) 171-185
11. Madeline T.L., and Peppas N.A. Molecular design and in vitro studies of novel pH-sensitive hydrogels for the oral delivery of calcitonin. Macromolecules 32 (1999) 6646-6651
12. Foss A.C., Goto T., Morishita M., and Peppas N.A. Development of acrylic-based copolymers for oral insulin delivery. Eur. J. Pharm. Biopharm. 57 (2004) 163-169
13. Katsu T., Mori Y., Furuno K., and Gomita Y. Mexiletine-sensitive membrane electrode for medical application. J. Pharm. Biomed. Anal. 19 (1999) 585-593
14. Bouklouze A.A., El Jammal A., Vire J.C., and Patriarche G.J. Comparative study of three polymeric membrane electrodes selective to tizanidine. Anal. Chim. Acta 257 (1992) 41-48
15. Aboul-Enein H.Y., and Sun X.X. A novel ion selective PVC membrane electrode for determination of propranolol in pharmaceutical formulation. Analusus 28 (2000) 855-858
16. Stefan R.I., Aboul-Enein H.Y., and Baiulescu G.E. Amiodarone-selective membrane electrode. Sens. Actuators, B 37 (1996) 141-144
17. Takisawa N., Hall D.G., Wyn-Jones E., and Brown P. The construction and characteristics of drug-selective electrodes. J. Chem. Soc., Faraday Trans. 1 84 (1988) 3059-3070
18. Alizadeh N., and Mehdipour R. Drug-selective electrode for ketamine determination in pharmaceutical preparations and electrochemical study of drug with BSA. J. Pharm. Biomed. Anal. 30 (2002) 725-731
19. Watanabe K., Okada K., Oda H., Furuno K., Gomita Y., and Katsu T. New cocaine-selective membrane electrode. Anal. Chim. Acta 316 (1995) 371-375
20. Srinivasan K., and Rechnitz G.A. Selectivity studies on liquid membrane, ion-selective electrodes. Anal. Chem. 41 (1969) 1203-1208