Discrimination of HERG carrier from non-carrier adult patients with borderline prolonged QTc interval

Computers in Cardiology

Volumn 32, Issue , 2005, Pages 125-128

  Couderc, J P ^a   Zareba, W ^a   Moss, A J ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROCARDIOGRAPHY; GENES; PATIENT TREATMENT; REGRESSION ANALYSIS; SENSITIVITY ANALYSIS; WAVE EFFECTS;

LETHAL ARRHYTHMIC EVENT; LONG QT SYNDROME (LQTS); REPOLARIZATION DURATION; T WAVE MORPHOLOGY;

MEDICAL PROBLEMS;

EID: 33847095125     PISSN: 02766574     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/CIC.2005.1588050     Document Type: Conference Paper

References (15)

1. Moss AJ, Schwartz PJ, Crampton RS, Locati E, Carleen E. The long QT syndrome: a prospective international study. Circulation 1985 Jan;71(1):17-21.
2. Yamaguchi M, Shimizu M, Ino H, Terai H, Uchiyama K, Oe K, et al. T wave peak-to-end interval and QT dispersion in acquired long QT syndrome: a new index for arrhythmogenicity. Clin Sci (Lond) 2003 Dec;105(6):671-6.
3. Lupoglazoff JM, Denjoy I, Berthet M, Hainque B, Vaksmann G, Klug D, et al. [T wave abnormalities on Holter monitoring of congenital long QT syndrome: phenotypic marker of a mutation of LQT2 (HERG)]. Arch Mal Coeur Vaiss 2001 May;94(5):470-8.
4. Couderc JP, Fareh S, Chevalier P, Fayn J, Kirkorian G, Rubel P, et al. Stratification of time-frequency abnormalities in the signal-averaged high-resolution ECG in postinfarction patients with and without ventricular tachycardia and congenital long QT syndrome. J Electrocardiol 1996;29 Suppl:180-8.
5. Moss AJ, Zareba W, Benhorin J, Locati EH, Hall WJ, Robinson JL, et al. ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome. Circulation 1995 Nov 15;92(10):2929-34.
6. Krahn AD, Klein GJ, Yee R. Hysteresis of the RT interval with exercise: a new marker for the long-QT syndrome? Circulation 1997 Sep 2;96(5):1551-6.
7. Kaufman ES, Priori SG, Napolitano C, Schwartz PJ, Iyengar S, Elston RC, et al. Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. J Cardiovasc Electrophysiol 2001 Apr;12(4):455-61.
8. Burattini L, Zareba W, Rashba EJ, Couderc JP, Konecki J, Moss AJ. ECG features of microvolt T-wave alternans in coronary artery disease and long QT syndrome patients. J Electrocardiol 1998;31 Suppl:114-20.
9. Couderc JP, Zareba W, Burattini L, Konecki JA, Moss AJ. Beat-to-beat repolarization variability in amplitude and duration in LQTS patients with the SCN5A sodium channel gene mutation. J Electrocardiol 1998;31 Suppl:134.
10. Couderc JP, Zareba W, Burattini L, Moss AJ. Beat-to-Beat repolarization variability in LQTS patients with the SCN5A sodium channel gene mutation. Pacing Clin Electrophysiol 1999 Nov;22(11):1581-92.
11. Moss AJ, Schwartz PJ, Crampton RS, Tzivoni D, Locati EH, MacCluer J, et al. The long QT syndrome. Prospective longitudinal study of 328 families. Circulation 1991 Sep;84(3):1136-44.
12. Badilini F, Erdem T, Zareba W, Moss AJ. ECGScan: a method for conversion of paper electrocardiographic printouts to digital electrocardiographic files. J Electrocardiol. In press 2005.
13. Couderc JP, Zareba W, Moss A.J. Drug-Induced Changes of Ventricular Repolarization: New Incentives for Quantifying T Wave Morphology. International Journal of Bioelectromagnetism; IEEE Computer Society Press; 2003 p. 167-70.
14. Lupoglazoff JM, Denjoy I, Berthet M, Neyroud N, Demay L, Richard P, et al. Notched T waves on Holter recordings enhance detection of patients with LQt2 (HERG) mutations. Circulation 2001 Feb 27;103(8):1095-101.
15. [15]Restier L, Fayn J, Rubel P, Millat G, Adeleine P, Rousson R, et al. Abnormal 3D ECG in long QT syndrome patients: A new phenotypic marker for HERG mutation. Circulation 110 (Supp)[17], III-622. 2004.