Randomised placebo-controlled trial on the effectiveness of nasal salmon calcitonin in the treatment of lumbar spinal stenosis

European Spine Journal

Volumn 16, Issue 2, 2007, Pages 207-212

  Tafazal, Suhayl I ^a   Ng, Leslie ^a   Sell, Philip ^a  

^a UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

Author keywords

Lumbar spinal stenosis; Nasal salmon calcitonin; Neurogenic claudication

Indexed keywords

PLACEBO; SALCATONIN; SODIUM CHLORIDE;

AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONSERVATIVE TREATMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COURSE EVALUATION; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; INTERMITTENT CLAUDICATION; LEG PAIN; LOW BACK PAIN; LUMBAR SPINE; MALE; MEDICAL ASSESSMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; OSWESTRY DISABILITY INDEX; OUTCOME ASSESSMENT; PHYSICAL DISABILITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHINORRHEA; SCORING SYSTEM; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; VERTEBRAL CANAL STENOSIS; VISUAL ANALOG SCALE; WALKING;

ADMINISTRATION, INTRANASAL; AGED; BONE DENSITY CONSERVATION AGENTS; CALCITONIN; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LUMBAR VERTEBRAE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PAIN MEASUREMENT; SEVERITY OF ILLNESS INDEX; SPINAL STENOSIS;

EID: 33847093395     PISSN: 09406719     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00586-006-0154-4     Document Type: Article

References (15)

1. Simotas A (2001) Nonoperative treatment for lumbar spinal stenosis. Clin Orthop 1(384):153-161
2. Porter RW, Hibbert C (1983) Calcitonin treatment for neurogenic claudication. Spine 8(6):585-592
3. Pratt RK, Fairbank JC, Virr A (2002) The reliability of the Shuttle Walking Test, the Swiss Spinal Stenosis Questionnaire, the Oxford Spinal Stenosis Score, and the Oswestry Disability Index in the assessment of patients with lumbar spinal stenosis. Spine 27(1):84-91
4. Fairbank J, Pynsent P (2000) The Oswestry Disability Index. Spine 25(22):2940-2953
5. Greenough CG, Fraser RD (1992) Assessment of outcome in patients with low back pain. Spine 17(1):36-41
6. Ellerington MC, Hillard TC, Whitcroft SI et al (1996) Intranasal salmon calcitonin for the prevention and treatment of postmenopausal osteoporosis. Calcif Tissue Int 59(1):6-11
7. Walpin LA, Singer FR (1979) Paget's disease, reversal of severe paraparesis with calcitonin. Spine 4:213-219
8. Douglas DL, Duckworth T, Kanis JA et al (1981) Spinal cord dysfunction in Paget's disease of bone. Has medical treatment a vascular basis? J Bone Joint Surg Br.63B(4):495-503
9. Podichetty VK, Segal AM, Lieber M, Mazanec DJ (2004) Effectiveness of Salmon calcitonin nasal spray in the treatment of lumbar canal stenosis. Spine 29(21):2343-2349
10. Porter RW, Miller CG (1988) Neurogenic claudication and root claudication treated with calcitonin. A double-blind trial. Spine 13(9):1061-1064
11. Streifler J, Hering R, Gadoth N (1989) Calcitonin for pseudoclaudication in lumbar spinal stenosis. J Neurol Neurosurg Psychiatry 52(4):543-544
12. Eskola A, Pohjolainen T, Alaranta H et al (1992) Calcitonin treatment in lumbar spinal stenosis: a randomized, placebo controlled, double-blind, cross-over study with one year follow-up. Calcif Tissue Int 50:400-403
13. Onel D, Sari H, Donmez C (1993) Lumbar spinal stenosis: clinical/radiologic therapeutic evaluation in 145 patients: conservative treatment or surgical intervention? Spine 18:291-298
14. Gennari C (1983) Clinical aspects of calcitonin in pain. Triangle 22(2/3):156-163
15. Eskola A, Alaranta H, Pohjolainen T et al (1989) Calcitonin treatment in lumbar spinal stenosis: clinical observations. Calcif Tissue Int 45:372-374