Clot structure modification by fondaparinux and consequence on fibrinolysis: A new mechanism of antithrombotic activity

Thrombosis and Haemostasis

Volumn 97, Issue 1, 2007, Pages 27-31

  Varin, Rémi ^a   Mirshahi, Shahsultan ^b   Mirshahi, Pezhman ^a,c,d   Kierzek, Gerald ^e   Sebaoun, David ^c,d   Mishal, Zohar ^f   Vannier, Jean Pierre ^a   Borg, Jeanne Yvonne ^a   Simoneau, Guy ^g   Soria, Claudine ^a   Soria, Jeannette ^c,d  

^a UNIVERSITÉ DE ROUEN   (France)

^b Stago R and D   (France)

^c INSERM   (France)

^d Laboratoire d'Onco Hématologie   (France)

^e HÔTEL DIEU   (France)

^f CNRS   (France)

^g HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Clot structure; Fibrin network; Fibronolysis; Fondaparinux

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN; BLOOD CLOTTING FACTOR 10A INHIBITOR; FONDAPARINUX; LOW MOLECULAR WEIGHT HEPARIN; THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR; THROMBOMODULIN;

ANTICOAGULATION; ARTICLE; BIOAVAILABILITY; BLOOD CLOT LYSIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; FIBRINOLYSIS; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; VENOUS THROMBOEMBOLISM;

ANTITHROMBIN III; BLOOD COAGULATION; FIBRIN; FIBRINOLYSIS; FIBRINOLYTIC AGENTS; KINETICS; POLYSACCHARIDES; PROTEIN CONFORMATION; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR;

EID: 33847072643     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-07-0394     Document Type: Article

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