The pathophysiology of chronic ischemic heart disease

Clinical Cardiology

Volumn 30, Issue SUPPL., 2007, Pages I-4-I-9

  Pepine, Carl J ^a   Nichols, Wilmer W ^a  

^a Division of Cardiovascular Medicine   (United States)

Author keywords

Atheroma; Atherothrombosis; Cardiac ischemia; Coronary perfusion; Energies; Ischemic preconditioning; NSTEMI; STEMI; Susceptible myocardium; Unstable angina pectoris; Vascular remodeling

Indexed keywords

ANTITHROMBIN III; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5 LEIDEN; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; CALCIUM ANTAGONIST; CALCIUM ION; CARDIOLIPIN ANTIBODY; DIMER; FASUDIL; FIBRINOGEN; FIBRINOGEN RECEPTOR; HEMOGLOBIN; LOW DENSITY LIPOPROTEIN; NICORANDIL; NITRIC ACID DERIVATIVE; PLASMINOGEN ACTIVATOR INHIBITOR 1; POTASSIUM ION; PROTEIN C; PROTEIN S; SODIUM ION; THROMBIN RECEPTOR; THROMBOMODULIN; TISSUE PLASMINOGEN ACTIVATOR; VON WILLEBRAND FACTOR;

ANGINA PECTORIS; ATHEROMA; ATHEROSCLEROTIC PLAQUE; BLOOD; CHRONIC DISEASE; CLINICAL PRACTICE; CORONARY ARTERY BLOOD FLOW; DIASTOLIC BLOOD PRESSURE; ENDOTHELIUM INJURY; HEART MUSCLE; HEART MUSCLE OXYGEN CONSUMPTION; HEART RATE; HUMAN; ION CURRENT; ISCHEMIC HEART DISEASE; ISCHEMIC PRECONDITIONING; OXYGEN SUPPLY; PATHOPHYSIOLOGY; QUALITY OF LIFE; REVIEW; SYMPTOM; SYSTEMATIC REVIEW; TREATMENT PLANNING; VASCULAR SMOOTH MUSCLE;

EID: 33847066275     PISSN: 01609289     EISSN: None     Source Type: Journal    
DOI: 10.1002/clc.20048     Document Type: Review

References (22)

1. Libby P, Theroux P: Pathophysiology of coronary artery disease. Circulation 2005;111:3481-3488
2. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, et al.: From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation 2003;108:1772-1778
3. Pepine CJ, Kerensky RA, Lambert CR, Smith KM, von Mering GO, et al.: Some thoughts on the vasculopathy of women with ischemic heart disease. J Am Coll Cardiol 2006;47:S30-S35
4. Esper RJ, Nordaby RA, Vilarino JO, Paragano A, Cacharron JL, et al.: Endothelial dysfunction: a comprehensive appraisal. Cardiovasc Diabetol 2006;5:4
5. Schoenhagen P, Nissen SE, Tuzcu EM: Coronary arterial remodeling: from bench to bedside. Curr Atheroscler Rep 2003;5:150-154
6. Kinlay S: What has intravascular ultrasound taught us about plaque biology? Curr Atheroscler Rep 2001;3:260-266
7. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ: Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987;316:1371-1375
8. Pepine CJ, Nichols WW, Pauly DF: Estrogen and different aspects of vascular disease in women and men. Circ Res 2006;99:459-461
9. Fujii K, Mintz GS, Carlier SG, Costa JR Jr, Kimura M, et al.: Intravascular ultrasound profile analysis of ruptured coronary plaques. Am J Cardiol 2006;98:429-435
10. Ferro G, Duilio C, Spinelli L, Liucci GA, Mazza F, et al.: Relation between diastolic perfusion time and coronary artery stenosis during stress-induced myocardial ischemia. Circulation 1995;92:342-347
11. Fukuda D, Yoshiyama M, Shimada K, Yamashita H, Ehara S, et al.: Relation between aortic stiffness and coronary flow reserve in patients with coronary artery disease. Heart 2006;92:759-762
12. Boutouyrie P, Tropeano AI, Asmar R, Gautier I, Benetos A, et al.: Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study. Hypertension 2002;39:10-15
13. O'Rourke MF, Nichols WW: Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension. Hypertension 2005;45:652-658
14. Hoffman JI: A critical view of coronary reserve. Circulation 1987;75:I6-I11
15. Watanabe H, Ohtsuka S, Kakihana M, Sugishita Y: Decreased aortic compliance aggravates subendocardial ischaemia in dogs with stenosed coronary artery. Cardiovasc Res 1992;26:1212-1218
16. Ohtsuka S, Kakihana M, Watanabe H, Sugishita Y: Chronically decreased aortic distensibility causes deterioration of coronary perfusion during increased left ventricular contraction. J Am Coll Cardiol 1994;24:1406-1414
17. Saeki A, Recchia F, Kass DA: systolic flow augmentation in hearts ejecting into a model of stiff aging vasculature. Influence on myocardial perfusion-demand balance. Circ Res 1995;76:132-141
18. Isoyama S, Maruyama Y, Ashikawa K, Sato S, Suzuki H, et al.: Effects of afterload reduction on global left ventricular and regional myocardial functions in the isolated canine heart with stenosis of a coronary arterial branch. Circulation 1983;67:139-147
19. Leung MC, Meredith IT, Cameron JD: Aortic stiffness affects the coronary blood flow response to percutaneous coronary intervention. Am J Physiol Heart Circ Physiol 2006;290:H624-H630
20. Arant CB, Wessel TR, Olson MB, Bairey Merz CN, Sopko G, et al.: Hemoglobin level is an independent predictor for adverse cardiovascular outcomes in women undergoing evaluation for chest pain: results from the National Heart, Lung, and Blood Institute Women's Ischemia Syndrome Evaluation Study. J Am Coll Cardiol 2004;43:2009-2014
21. Massberg S, Schulz C, Gawaz M: Role of platelets in the pathophysiology of acute coronary syndrome. Semin Vasc Med 2003;3:147-162
22. Lee TM, Lin MS, Tsai CH, Chang NC: Effect of ischaemic preconditioning on regional release of inflammatory markers. Clin Sci (Lond) 2005;109:267-276