Specific stabilization of DNA triple helices by indolo[2,1-b]quinazolin-6,12-dione derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 6, 2007, Pages 1769-1772

  Chen, Grace Shiahuy ^a   Bhagwat, Bhalchandra V ^b   Liao, Pei Yin ^b   Chen, Hui Ting ^b   Lin, Shwu Bin ^c   Chern, Ji Wang ^b  

^a PROVIDENCE UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

DNA triplex; Indolo 2,1 b quinazolin 6,12 dione; Thermal denaturation; Triplex stabilizing agents; Tryptanthrin

Indexed keywords

ALIPHATIC AMINE; AMINE; DNA; FLUORINE; INDOLO[2,1 B]QUINAZOLINE 6,12 DIONE DERIVATIVE; NITROGEN; QUINAZOLINE DERIVATIVE; TRYPTANTHRINE; UNCLASSIFIED DRUG;

ARTICLE; DNA CONFORMATION; DNA HELIX; DNA SYNTHESIS; DRUG CONFORMATION; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR STABILITY; NONHUMAN; STRUCTURE ANALYSIS;

CHEMISTRY, PHYSICAL; CIRCULAR DICHROISM; DNA; INDOLES; LIGANDS; NUCLEIC ACID CONFORMATION; PHYSICOCHEMICAL PHENOMENA; QUINAZOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33847063197     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.079     Document Type: Article

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