Effects of in ovo exposure to PCBs 126 and 77 on mortality, deformities and post-hatch immune function in chickens

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 70, Issue 6, 2007, Pages 547-558

  Lavoie, E T ^a   Grasman, K A ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b CALVIN COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,3',4,4' TETRACHLOROBIPHENYL; 3,3',4,4',5 PENTACHLOROBIPHENYL; PHYTOHEMAGGLUTININ;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BIRD; CELLULAR IMMUNITY; CONTROLLED STUDY; DEFORMITY; EGG; FEMALE; FERTILE PERIOD; HATCHING; IMMUNE FUNCTION TEST; IMMUNOTOXICITY; INCUBATION TIME; JUVENILE ANIMAL; LYMPHOCYTE PROLIFERATION; MALE; MITOGENESIS; MORTALITY; NONHUMAN; ORGANOGENESIS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SHEEP ERYTHROCYTE; SKIN MANIFESTATION; SKIN TEST; SYNOVIAL BURSA; THYMUS;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; BURSA OF FABRICIUS; CELL PROLIFERATION; CHICK EMBRYO; CHICKENS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LYMPHOCYTES; MALE; OVUM; PHYTOHEMAGGLUTININS; POLYCHLORINATED BIPHENYLS; POULTRY DISEASES; SPLEEN; THYMUS GLAND; WATER POLLUTANTS, CHEMICAL;

AVES; GALLUS GALLUS; OVIS ARIES; SPONDIAS PURPUREA;

EID: 33847048592     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390600882226     Document Type: Article

References (49)

1. Bargar T. A., Scott G. I., Cobb G. P. 2001. Uptake and distribution of three PCB congeners and endosulfan by developing white leghorn chicken embryos (Gallus domesticus). Arch Environ Contam Toxicol 41:508-514.
2. Burleson G. R., Lebrec H., Yang Y. G., Ibanes J. D., Pennington K. N., and Birnbaum L. S. 1996. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on influenza virus host resistance in mice. Fundam Appl. Toxicol 29:40-47.
3. Bustnes J. O., Hanssen S. A., Folstad I., Erikstad K. E., Hasselquist D., Skaare, J. U. 2004. Immune function and organochlorine pollutants in arctic breeding glaucous gulls. Arch Environ Contam Toxicol 47:530-541.
4. Bustnes J. O. 2006. Pinpointing potential causative agents in mixtures of persistent organic pollutants in observational field studies: A review of glaucous gull studies. J Toxicol Environ Health A 69:97-108.
5. Corrier D. E., and DeLoach J. R. 1990. Evaluation of cell-mediated, cutaneous basophil hypersensitivity in young chickens by an interdigital skin test. Poult Sci 69:403-408.
6. De Heer C., Verlaan A. P. J., Penninks A. H., Vos J. G., Schuurman H. J., and Van Loveren H. 1994. Time course of 2,3,7,8-tetrachlorodibenzo-p- dioxin (TCDD)-induced thymic atrophy in the Wistar rat. Toxicol Appl Pharmacol 128:97-104.
7. De Swart R., Ross P., Vedder L., Timmerman H., Heisterkamp S., Van Loveren H., Vos J. G., Reijnders P. J. H., and Osterhaus A. 1994. Impairment of immune function in harbor seals (Phoca vitulina) feeding on fish from polluted waters. Ambio 23:155-159.
8. Esser C., Lai Z. W., and Gleichmann E. 1994. Proliferation inhibition and CD4/CD8 thymocyte subset skewing by in vivo exposure of C57BL/6 mice to Ah receptor binding 3,3,4,4′-tetrachlorobiphenyl. Exp Clin Immunogen 11:75-85.
9. Fairbrother A., Smits J., Grasman K. A. 2004. Avian Immunotoxicology. J Toxicol Environ Health B 7:105-137.
10. Faith R. E., and Moore J. A. 1977. Impairment of thymus-dependent immune functions by exposure of the developing immune system to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD). J Toxicol Environ Health 3:451-464.
11. Fowles J. R., Fairbrother A., Trust K. A., Kerkvliet N. I. 1997. Effects of aroclor 1254 on the thyroid gland, immune function, and hepatic cytochrome P450 activity in mallards. Environ Res 75: 119-129.
12. Fox L. A., and Grasman K. A. 1999. Effects of PCB 126 on primary immune organ development in chicken embryos. J. Toxicol. Environ. Health 58:101-112.
13. Friend, M. and D. O. Trainer. 1970. Polychlorinated biphenyl: interaction with duck hepatitis virus. Science 170:1314.
14. Goff K. F. 2002. Developmental effects of PCBs on apoptosis and the primary immune organs in white leghorn chicken embryos. Ph.D. Dissertation. Dayton, OH: Wright State University.
15. Goff K. F., Hull B. E., and Grasman K. A. 2005 Effects of PCB 126 on primary immune organs and thymocyte apoptosis in chicken embryos. J. Toxicol. Environ. Health. Part A.65:485-500.
16. Grasman K. A., Fox G. A., Scanlon P. F., and Ludwig J. P. 1996. Organochlorine-associated immunosuppression in prefledgling Caspian terns and herring gulls from the Great Lakes: An ecoepidemiological study. Environ Health Persp 104:829-842.
17. Grasman K. A., and Whitacre L. L. 2001. Effects of PCB 126 on the thymocytes surface marker expression and immune organ development in chicken embryos. J Toxicol Environ Health, Part A 62:191-206.
18. Grasman K. A., Fox G. A. 2001. Associations between altered immune function and organochlorine contamination in young Caspian terns (Sterna caspia) from Lake Huron, 1997-1999. Ecotoxicology 10:101-114.
19. Grasman K. A. 2002. Assessing immunological function in toxicological studies of avian wildlife. Integr Comp Biol 42, 34-42.
20. Harper N., Connor K., Steinberg M., and Safe S. 1995. Immunosuppressive activity of polychlorinated biphenyl mixtures and congeners: nonadditive (antagonistic) interactions. Fundam Appl Toxicol 27:131-139.
21. Harris S. J., Cecil H. C., Bitman J., and Lillie R. J. 1976. Antibody response and reduction in bursa of fabricius and spleen weights of progeny of chickens fed PCBs. Poult Sci 55:1933-1940.
22. Henshel D. S., Hehn B., Wagey R., Vo M., Steeves J. D. 1997. The relative sensitivity of chicken embryos to yolk- or air-cell-injected 2,3,7,8-tetrachlorodibenzo-p-dioxin. Environ Tox Chem 16: 725-732.
23. Holladay S. D., Lindstrom P., Blaylock B. L., Comment C. E., Germolec D. R., Heindell J. J., and Luster M. I. 1991. Perinatal thymocyte antigen expression and postnatal immune development altered by gestational exposure to tetrachlorodibenzo-p-dioxin (TCDD). Teratology 44:385-393.
24. Hollander M., Wolfe D. A. 1973. Nonparametric Statistical Methods. John Wiley and Sons, New York, New York, USA.
25. Hovi T., Suni J., Hortling L., Vaheri A. 1978. Stimulation of chicken lymphocytes by T- and B-cell mitogens. Cell Immunol 39:70-78.
26. Jepson P. D., Bennett P. M., Deaville R., Allchin C. R., Baker, J. R., Law R. J. 2005. Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom. Environ Tox Chem, 24: 238-248.
27. Kosutzky J., Kosutzka E., Lencuchova L. 1993. Long-term exposure to PCB in broiler chickens-metabolic and immunotoxic effects. Vet Med 38:287-296.
28. Latimer J. W., Siegel H. S. 1974. Immune response in broilers fed technical grade DDT. Poult Sci 53:1078-1084.
29. Lavoie E. T., Grasman K. A. 2005. Isolation, cryopreservation and mitogenesis of peripheral blood lymphocytes from chickens (Gallus domesticus) and herring gulls (Larus argentatus). Arch Environ Contam Toxicol 48:552-558.
30. Ludwig J. P., Kurita-Matsuba H., Auman H. J., Ludwig M. E., Summer C. L., Giesy J. P., Tillitt D. E., Jones P. D. 1996. Deformities, PCBs, and TCDD-equivalents in double crested cormorants (Phalacrocorax auritus) and Caspian terns (Hydroprogne caspia) of the upper Great Lakes 1986-1991: Testing a cause-effect hypothesis. J Great Lakes Res 22:172-197.
31. Luster M. I., Portier C., Pait D., Rosenthal G., Germolec D. R., Corsini E., Blaylock B. L., Pollock P., Kouchi Y., Craig W., White K., Munson A. E., Comment C. E. 1993. Risk assessment in immunotoxicology. II. Relationships between immune and host resistance tests. Fundam ApplToxicol 21:71-82.
32. Natt M. P., Herrick C. A. 1952. A new blood diluent for counting the erythrocytes and leucocytes of the chicken. Poult Sci 31: 735-738.
33. Peden-Adams M. K., Alonso C., Godard W., Mashburn J., Hoover C., Charbonneau C., Henshel D., Dickerson R. 1998. Effects of environmentally relevant concentrations of 2,3,7,8-TCDD on domestic chicken immune function and CYP450 activity: F1 generation and egg injection studies. Chemosphere 37:1923-1939.
34. Pekarik C., Weseloh D. V., Barrett G. C., Simon M., Bishop C. A., Pettit K. E. 1998. An atlas of contaminants in the eggs of fish-eating colonial birds of the Great Lakes (1993-1997), volume II: Accounts by chemical. Technical report series no.321, Canadian Wildlife Service, Ontario Region.
35. Powell D. C., Aulerich R. J., Meadows J. C., Tillitt D. E., Giesy J. P., Stromborg K. L., Bursian S. J. 1996. Effects of 3,3′,4,4′,5- pentachlorobiphenyl (PCB 126) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) injected into the yolks of chicken (Gallus domesticus) eggs prior to incubation. Arch Environ Contam Toxicol 31:404-409.
36. Ross P., De Swart R., Reijnders P. J. H., Van Loveren H., Vos J. G., Osterhaus A. 1995. Contaminant-related suppression of delayed-type hypersensitivity and antibody responses in harbor seals fed herring from the Baltic sea. Environ Health Perspect 103:162-167.
37. Ross P., De Swart R., van der Vliet H., Willemsen L., de Klerk A., van Amerongen G., Groen J., Brouwer J., Schipholt I., Morse D. C., Van Loveren H., Osterhaus A., Vos J. G. 1997. Impaired cellular immune response in rats exposed perinatally to Baltic Sea herring oil or 2,3,7,8-TCDD. Arch Toxicol 17:563-574.
38. Sagerup K., Henriksen E. O., Skorping A., Skaare J. U., Gabrielsen G. W. 2000. Intensity of parasitic nematodes increases with organochlorine levels in glaucous gull. J Appl Ecol 3:532-539.
39. Sanderson J. T., Kennedy S. W., Giesy J. P. 1998. In vitro induction of ethoxyresorufin-o-deethylase and porphyrins by halogenated aromatic hydrocarbons in avian primary hepatocytes. Environ Toxicol Chem 17:2006-2018.
40. Segre M., Arena S. M., Greeley E. H., Melancon M. J., Graham D. A., French J. J. B. 2002. Immunological and physiological effects of chronic exposure of Peromyscus leucopus to Aroclor 1254 at a concentration similar to that found at contaminated sites. Toxicology 174:163-172.
41. Smialowicz R. J., DeVito M. J., Riddle M. M., Williams W. C., Birnbaum L. S. 1997. Opposite effects of 2,2′,4,4′,5,5′- hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antibody response to sheep erythrocytes in mice. Fundam Appl Toxicol 37:141-149.
42. Stadecker M. J., Lukic M., Dvorak A., Leskowitz S. 1977. The cutaneous basophil response to phytohemagglutinin in chickens. J Immunol 118:1564-1568.
43. Thomas P. T., Hinsdill R. D. 1978. Effect of polychlorinated biphenyls on the immune responses of Rhesus monkeys and mice. Toxicol Appl Pharmacol 44:41-51.
44. Tryphonas H. 1995. Immunotoxicity of PCBs (Aroclors) in relation to Great Lakes. Environ Health Perspect 103:35-46.
45. Van Loveren H. V., Ross P. S., Osterhaus A. D. M. E., Vos J. G. 2000. Contaminant-induced immunosuppression and mass mortalities among harbor seals. Toxicol Lett 112-113:319-324.
46. Van den Berg M., Craane B. L. H. J., Sinnige T., van Mourik S., Dirksen S., Boudewin T., van der Gaag M., Lutke-Schipholt I. J., Spenkelink B., Brouwer A. 1994. Biochemical and toxic effects of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in the cormorant (Phalacrocorax carbo) after in ovo exposure. Environ Toxicol Chem 13: 803-816.
47. Van den Berg M., Birnbaum L. S., Bosveld A. T. C., Brunstrom B., Cook M., Feeley, Giesy J. P., Hanberg A., Hasegawa R., Kennedy S. W., Kubiak T., Larsen J. C., Rolaf van Leeuwen F. X., Djien Liem A. K., Nolt C., Peterson R. E., Poellinger L., Safe S., Schrenk D., Tillitt D. E., Tysklind M., Younes M., Waern F., Zachharewski T. 1998. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Persp 106:775-792.
48. Weisglas-Kuperus N. S., Patankin G., Berbers T., Sas P., Mulder P., Sauer P., Hooijkaas H. 2000. Immunologic effects of background exposure to polychlorinated biphenyls and dioxins in Dutch preschool children. Environ Health Persp 108:1203-1207.
49. Wu P. J., Greeley E. H., Hansen L. G., Segre M. 1999. Immunological, hematological and biochemical responses in immature white-footed mice following maternal Aroclor 1254 exposure: a possible bioindicator. Arch Environ Contam Toxicol 36:469-476.