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Volumn 12, Issue 4, 2006, Pages 197-204

Detection of HER-2/neu gene amplification in breast carcinomas using quantitative real-time PCR - A comparison with immunohistochemical and FISH results

Author keywords

Breast carcinoma; FISH; HER 2 neu DNA amplification; HER 2 neu protein; Immunohistochemistry; LightCycler RT PCR system; Quantitative RT PCR

Indexed keywords

ANTIBODY; CB11 ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

EID: 33847043534     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02893412     Document Type: Article
Times cited : (33)

References (43)
  • 1
    • 0026576399 scopus 로고
    • HER-2/neu in node-negative breast cancer: Prognostic significance of overexpression influenced by the presence of in situ carcinoma
    • Allred DC, Clark GM, Molina R, et al: HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma. J Clin Oncol 10: 599-605, 1992
    • (1992) J Clin Oncol , vol.10 , pp. 599-605
    • Allred, D.C.1    Clark, G.M.2    Molina, R.3
  • 2
    • 9944234506 scopus 로고    scopus 로고
    • Comparison of automated and manual determination of HER2 status in breast cancer for diagnostic use: A comparative methodological study using Ventana BenchMark automated staining system and manual tests
    • Bánkfalvi A, Boecker W, Reiner A: Comparison of automated and manual determination of HER2 status in breast cancer for diagnostic use: a comparative methodological study using Ventana BenchMark automated staining system and manual tests. Int J Oncol 25: 929-935, 2004
    • (2004) Int J Oncol , vol.25 , pp. 929-935
    • Bánkfalvi, A.1    Boecker, W.2    Reiner, A.3
  • 3
    • 3142723629 scopus 로고    scopus 로고
    • Relationship between HER2 status and proliferation rate in breast cancer assessed by immunohistochemistry, fluorescence in situ hybridisation and standardised AgNOR analysis
    • Bánkfalvi A, Giuffre G, Ofner D, et al: Relationship between HER2 status and proliferation rate in breast cancer assessed by immunohistochemistry, fluorescence in situ hybridisation and standardised AgNOR analysis. Int J Oncol 23: 1285-1292, 2003
    • (2003) Int J Oncol , vol.23 , pp. 1285-1292
    • Bánkfalvi, A.1    Giuffre, G.2    Ofner, D.3
  • 4
    • 85044702633 scopus 로고    scopus 로고
    • HER-2 diagnostics
    • In Hungarian
    • Bánkfalvi Á: HER-2 diagnostics. Magy Onkol 46: 11-15, 2002 [In Hungarian]
    • (2002) Magy Onkol , vol.46 , pp. 11-15
    • Bánkfalvi, A.1
  • 5
    • 0022600388 scopus 로고
    • The neu oncogene encodes an epidermal growth factor receptor-related protein
    • Bargmann CI, Hung MC, Weinberg RA: The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature 319: 226-230, 1986
    • (1986) Nature , vol.319 , pp. 226-230
    • Bargmann, C.I.1    Hung, M.C.2    Weinberg, R.A.3
  • 6
    • 0035162262 scopus 로고    scopus 로고
    • Evaluating HER2 amplification and overexpression in breast cancer
    • Bartlett JM, Going JJ, Mallon EA, et al: Evaluating HER2 amplification and overexpression in breast cancer. J Pathol 195: 422-428, 2001
    • (2001) J Pathol , vol.195 , pp. 422-428
    • Bartlett, J.M.1    Going, J.J.2    Mallon, E.A.3
  • 8
    • 33847064416 scopus 로고    scopus 로고
    • PCR is a powerful tool to assess HER2/neu positivity in breast cancer
    • Beyser K, Reiser A, Gross C, et al: PCR is a powerful tool to assess HER2/neu positivity in breast cancer. Eur J Cancer 158: 419-429, 2001
    • (2001) Eur J Cancer , vol.158 , pp. 419-429
    • Beyser, K.1    Reiser, A.2    Gross, C.3
  • 9
    • 0038216586 scopus 로고    scopus 로고
    • Predicting the HER2 status of breast cancer from basic histopathology data: An analysis of 1500 breast cancers as part of the HER2000 international study
    • Bilous M, Ades C, Armes J, et al: Predicting the HER2 status of breast cancer from basic histopathology data: an analysis of 1500 breast cancers as part of the HER2000 international study. Breast 12: 92-98, 2003
    • (2003) Breast , vol.12 , pp. 92-98
    • Bilous, M.1    Ades, C.2    Armes, J.3
  • 10
    • 0001650264 scopus 로고    scopus 로고
    • Clinical significance of HER-2/neu overexpression: Part I
    • DiGiovanna MP: Clinical significance of HER-2/neu overexpression: Part I. Principles and Practice of Oncology 13: 1-10, 1999
    • (1999) Principles and Practice of Oncology , vol.13 , pp. 1-10
    • MP, D.1
  • 11
    • 1542503725 scopus 로고    scopus 로고
    • HER-2 testing and trastuzumab therapy for metastatic breast cancer: A cost-effectiveness analysis
    • Elkin EB, Weinstein MC, Winer EP, et al: HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis. J Clin Oncol 22: 854-863, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 854-863
    • Elkin, E.B.1    Weinstein, M.C.2    Winer, E.P.3
  • 12
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long term follow up
    • Elston CW, Ellis IO: Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long term follow up. Histopathology 19: 403-410, 1991
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 13
    • 9144267697 scopus 로고    scopus 로고
    • Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma
    • Esteva FJ, Sahin AA, Smith TL, et al: Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma. Cancer 100: 499-506, 2004
    • (2004) Cancer , vol.100 , pp. 499-506
    • Esteva, F.J.1    Sahin, A.A.2    Smith, T.L.3
  • 14
    • 1142263115 scopus 로고    scopus 로고
    • Real-time quantitative PCR of microdissected paraffin-embedded breast carcinoma
    • Gjerdrum LM, Sorensen BS, Kjeldsen E, et al: Real-time quantitative PCR of microdissected paraffin-embedded breast carcinoma. J Mol Diagn 6: 42-51, 2004
    • (2004) J Mol Diagn , vol.6 , pp. 42-51
    • Gjerdrum, L.M.1    Sorensen, B.S.2    Kjeldsen, E.3
  • 15
    • 0024217624 scopus 로고
    • Immunohistochemical distribution of c-erbB-2 in infiltrating and in situ breast cancer
    • Gusterson BA, Machin LG, Gullick WJ, et al: Immunohistochemical distribution of c-erbB-2 in infiltrating and in situ breast cancer. Int J Cancer 42: 842-845, 1988
    • (1988) Int J Cancer , vol.42 , pp. 842-845
    • Gusterson, B.A.1    Machin, L.G.2    Gullick, W.J.3
  • 16
    • 0142169919 scopus 로고    scopus 로고
    • Strong HER-2/neu protein overexpression by immunohistochemistry often does not predict oncogene amplification by fluorescence in situ hybridization
    • Hammock L, Lewis M, Phillips C, et al: Strong HER-2/neu protein overexpression by immunohistochemistry often does not predict oncogene amplification by fluorescence in situ hybridization. Hum Pathol 34: 1043-1047, 2003
    • (2003) Hum Pathol , vol.34 , pp. 1043-1047
    • Hammock, L.1    Lewis, M.2    Phillips, C.3
  • 17
    • 0033109529 scopus 로고    scopus 로고
    • HER-2/neu gene amplification by fluorescence in situ hybridization allows risk-group assessment in node negative breast cancer
    • Harbeck N, Ross JS, Yurdseven S, et al: HER-2/neu gene amplification by fluorescence in situ hybridization allows risk-group assessment in node negative breast cancer. Int J Oncol 14: 663-671, 1999
    • (1999) Int J Oncol , vol.14 , pp. 663-671
    • Harbeck, N.1    Ross, J.S.2    Yurdseven, S.3
  • 18
    • 0033996013 scopus 로고    scopus 로고
    • HER-2/neu protein expression in breast cancer evaluated by immunohistochemistry; a study of interlaboratory agreement
    • Jacobs TW, Gown AM, Yaziji H, et al: HER-2/neu protein expression in breast cancer evaluated by immunohistochemistry; a study of interlaboratory agreement. Am J Clin Pathol 113: 251-258, 2000
    • (2000) Am J Clin Pathol , vol.113 , pp. 251-258
    • Jacobs, T.W.1    Gown, A.M.2    Yaziji, H.3
  • 19
    • 0033973884 scopus 로고    scopus 로고
    • Determination of Her-2/Neu status in breast carcinoma: Comparative analysis of immunohistochemistry and fluorescent in situ hybridization
    • Jimenez RE, Wallis T, Tabasczka P, Visscher DW: Determination of Her-2/Neu status in breast carcinoma: comparative analysis of immunohistochemistry and fluorescent in situ hybridization. Mod Pathol 13: 37-45, 2000
    • (2000) Mod Pathol , vol.13 , pp. 37-45
    • Jimenez, R.E.1    Wallis, T.2    Tabasczka, P.3    Visscher, D.W.4
  • 20
    • 0033785293 scopus 로고    scopus 로고
    • HER-2/neu assessment in breast cancer by immunohistochemistry and fluorescence in situ hybridization: Comparison of results and correlation with survival
    • Kakar S, Puangsuvan N, Stevens JM, et al: HER-2/neu assessment in breast cancer by immunohistochemistry and fluorescence in situ hybridization: comparison of results and correlation with survival. Mol Diagn 5: 199-207, 2000
    • (2000) Mol Diagn , vol.5 , pp. 199-207
    • Kakar, S.1    Puangsuvan, N.2    Stevens, J.M.3
  • 21
    • 1342322682 scopus 로고    scopus 로고
    • Effects of Herceptin treatment on global gene expression patterns in HER2-amplified and nonamplified breast cancer cell lines
    • Kauraniemi P, Hautaniemi S, Autio R, et al: Effects of Herceptin treatment on global gene expression patterns in HER2-amplified and nonamplified breast cancer cell lines. Oncogene 23: 1010-1013, 2004
    • (2004) Oncogene , vol.23 , pp. 1010-1013
    • Kauraniemi, P.1    Hautaniemi, S.2    Autio, R.3
  • 22
    • 0035863284 scopus 로고    scopus 로고
    • Her-2/neu analysis in archival tissue samples of human breast cancer: Comparison of immunohistochemistry and in situ hybridization
    • Lebeau A, Deimling D, Kaltz C, et al: Her-2/neu analysis in archival tissue samples of human breast cancer: Comparison of immunohistochemistry and in situ hybridization. J Clin Oncol 19: 354-363, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 354-363
    • Lebeau, A.1    Deimling, D.2    Kaltz, C.3
  • 23
    • 0042662574 scopus 로고    scopus 로고
    • Histological tumor grade correlates with HER2/c-erB-2 status in invasive breast cancer: A comparative analysis between immunohistochemical (CB11 clone and Herceptest)
    • Lopez-Guerrero JA, Navarro S, Noguera R, et al: Histological tumor grade correlates with HER2/c-erB-2 status in invasive breast cancer: a comparative analysis between immunohistochemical (CB11 clone and Herceptest), FISH and differential PCR procedures. Arkh Patol 65: 50-55, 2003
    • (2003) FISH and differential PCR procedures. Arkh Patol , vol.65 , pp. 50-55
    • Lopez-Guerrero, J.A.1    Navarro, S.2    Noguera, R.3
  • 24
    • 0347694720 scopus 로고    scopus 로고
    • Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells
    • Lu Y, Zi X, Zhao Y, Pollak M: Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells. Biochem Biophys Res Commun 313: 709-715, 2004
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 709-715
    • Lu, Y.1    Zi, X.2    Zhao, Y.3    Pollak, M.4
  • 25
    • 11144357873 scopus 로고    scopus 로고
    • Discordant results obtained for different methods of HER-2/neu testing in breast cancer - a question of standardization, automation and timing
    • Luftner D, Henschke P, Kafka A, et al: Discordant results obtained for different methods of HER-2/neu testing in breast cancer - a question of standardization, automation and timing. Int J Biol Markers 19: 1-13, 2004
    • (2004) Int J Biol Markers , vol.19 , pp. 1-13
    • Luftner, D.1    Henschke, P.2    Kafka, A.3
  • 26
    • 20444457037 scopus 로고    scopus 로고
    • Polysomy 17 in HER-2/neu status elaboration in breast cancer: Effect on daily practice
    • Ma Y, Lespagnard L, Durbecq V, et al: Polysomy 17 in HER-2/neu status elaboration in breast cancer: effect on daily practice. Clin Cancer Res 11: 4393-4399, 2005
    • (2005) Clin Cancer Res , vol.11 , pp. 4393-4399
    • Ma, Y.1    Lespagnard, L.2    Durbecq, V.3
  • 27
    • 33644545384 scopus 로고    scopus 로고
    • Real-time PCR complements immunohistochemistry in the determination of HER-2/neu status in breast cancer
    • doi:10.1186/1472-6890-6-2
    • Nistor A, Watson PH, Pettigrew N, et al: Real-time PCR complements immunohistochemistry in the determination of HER-2/neu status in breast cancer. BMC Clin Pathol 6:2 doi:10.1186/1472-6890-6-2, 2006
    • (2006) BMC Clin Pathol , vol.6 , pp. 2
    • Nistor, A.1    Watson, P.H.2    Pettigrew, N.3
  • 28
    • 0035064429 scopus 로고    scopus 로고
    • Comparison of HER2/neu status assessed by quantitative polymerase chain reaction and immunohistochemistry
    • O'Malley FP, Parkes R, Latta E, et al: Comparison of HER2/neu status assessed by quantitative polymerase chain reaction and immunohistochemistry. Am J Clin Pathol 115: 504-511, 2001
    • (2001) Am J Clin Pathol , vol.115 , pp. 504-511
    • O'Malley, F.P.1    Parkes, R.2    Latta, E.3
  • 29
    • 0026772869 scopus 로고
    • C-myc, c-erbB-2, and Ki-67 expression in normal breast tissue and in invasive and noninvasive breast carcinoma
    • Pavelic ZP, Pavelic L, Lower EE, et al: C-myc, c-erbB-2, and Ki-67 expression in normal breast tissue and in invasive and noninvasive breast carcinoma. Cancer Res 52: 2597-2606, 1992
    • (1992) Cancer Res , vol.52 , pp. 2597-2606
    • Pavelic, Z.P.1    Pavelic, L.2    Lower, E.E.3
  • 30
    • 0036161321 scopus 로고    scopus 로고
    • HER2 testing in patients with breast cancer: Poor correlation between weak positivity by immunohistochemistry and gene amplification by fluorescence in situ hybridization
    • Perez EA, Roche PC, Jenkins RB, et al: HER2 testing in patients with breast cancer: poor correlation between weak positivity by immunohistochemistry and gene amplification by fluorescence in situ hybridization. Mayo Clin Proc 77: 148-154, 2002
    • (2002) Mayo Clin Proc , vol.77 , pp. 148-154
    • Perez, E.A.1    Roche, P.C.2    Jenkins, R.B.3
  • 31
    • 0037099732 scopus 로고    scopus 로고
    • Evaluation of HER-2/neu gene amplification and overexpression: Comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens
    • Press MF, Slamon DJ, Flom KJ, et al: Evaluation of HER-2/neu gene amplification and overexpression: comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens. J Clin Oncol 20: 3095-3105, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 3095-3105
    • Press, M.F.1    Slamon, D.J.2    Flom, K.J.3
  • 32
    • 0030870422 scopus 로고    scopus 로고
    • Identification of HER-2/neu oncogene amplification by fluorescence in situ hybridization in stage I endometrial carcinoma
    • Riben MW, Malfetano JH, Nazeer T, et al: Identification of HER-2/neu oncogene amplification by fluorescence in situ hybridization in stage I endometrial carcinoma. Mod Pathol 10: 823-831, 1997
    • (1997) Mod Pathol , vol.10 , pp. 823-831
    • Riben, M.W.1    Malfetano, J.H.2    Nazeer, T.3
  • 33
    • 0033871534 scopus 로고    scopus 로고
    • HER-2/neu testing in breast carcinoma: A combined immunohistochemical and fluorescence in situ hybridization approach
    • Ridolfi RL, Jamehdor MR, Arber JM: HER-2/neu testing in breast carcinoma: A combined immunohistochemical and fluorescence in situ hybridization approach. Mod Pathol 13: 866-873, 2000
    • (2000) Mod Pathol , vol.13 , pp. 866-873
    • Ridolfi, R.L.1    Jamehdor, M.R.2    Arber, J.M.3
  • 34
    • 0033500183 scopus 로고    scopus 로고
    • The HER2/neu (c-erbB-2) gene and protein in breast cancer
    • Ross JS, Fletcher JA: The HER2/neu (c-erbB-2) gene and protein in breast cancer. Am J Clin Pathol 112 (Suppl 1): 553-567, 1999
    • (1999) Am J Clin Pathol , vol.112 , Issue.SUPPL. 1 , pp. 553-567
    • Ross, J.S.1    Fletcher, J.A.2
  • 35
    • 0027517374 scopus 로고
    • Clinical significance of HER-2/neu oncogene amplification in primary breast cancer. The South Australian Breast Cancer Study Group
    • Seshadri R, Figaira FA, Horsfall DJ, et al: Clinical significance of HER-2/neu oncogene amplification in primary breast cancer. The South Australian Breast Cancer Study Group. J Clin Oncol 11: 1936-1942, 1993
    • (1993) J Clin Oncol , vol.11 , pp. 1936-1942
    • Seshadri, R.1    Figaira, F.A.2    Horsfall, D.J.3
  • 36
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, et al: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177-182, 1987
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 37
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon DJ, Godolphin W, Jones LA, et al: Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244: 707-712, 1989
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3
  • 38
    • 0026500084 scopus 로고
    • C-erbB-2 overexpression and histological type of in situ and invasive breast carcinoma
    • Somerville JE, Clarke LA, Biggart JD: C-erbB-2 overexpression and histological type of in situ and invasive breast carcinoma. J Clin Pathol 45: 16-20, 1992
    • (1992) J Clin Pathol , vol.45 , pp. 16-20
    • Somerville, J.E.1    Clarke, L.A.2    Biggart, J.D.3
  • 39
    • 7744220150 scopus 로고    scopus 로고
    • Real-time PCR quantification of c-erbB-2 gene is an alternative for FISH in the clinical management of breast carcinoma patients
    • Suo Z, Daehli KU, Lindboe CF, et al: Real-time PCR quantification of c-erbB-2 gene is an alternative for FISH in the clinical management of breast carcinoma patients. Int J Surg Pathol 12: 311-318, 2004
    • (2004) Int J Surg Pathol , vol.12 , pp. 311-318
    • Suo, Z.1    Daehli, K.U.2    Lindboe, C.F.3
  • 40
    • 0031982086 scopus 로고    scopus 로고
    • Cytoplasmic staining of c-erbB-2 is not associated with the presence of detectable c-erbB-2 mRNA in breast cancer specimens
    • Taylor SL, Platt-Higgins A, Rudland PS, et al: Cytoplasmic staining of c-erbB-2 is not associated with the presence of detectable c-erbB-2 mRNA in breast cancer specimens. Int J Cancer 76: 459-463, 1998
    • (1998) Int J Cancer , vol.76 , pp. 459-463
    • Taylor, S.L.1    Platt-Higgins, A.2    Rudland, P.S.3
  • 41
    • 85039195845 scopus 로고    scopus 로고
    • th European Breast Cancer Conference, Hamburg, 395, 2004
    • th European Breast Cancer Conference, Hamburg, 395, 2004
  • 42
    • 0023736334 scopus 로고
    • Neu protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer
    • Van de Vijver M, Peterse JL, Mooi WJ, et al: Neu protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer. N Engl J Med 319: 1239-1245, 1988
    • (1988) N Engl J Med , vol.319 , pp. 1239-1245
    • Van de Vijver, M.1    Peterse, J.L.2    Mooi, W.J.3
  • 43
    • 0037352352 scopus 로고    scopus 로고
    • p38MAPK induces cell surface alpha4 integrin downregulation to facilitate erbB-2-mediated invasion
    • Woods Ignatoski KM, Grewal NK, Markwart S, et al: p38MAPK induces cell surface alpha4 integrin downregulation to facilitate erbB-2-mediated invasion. Neoplasia 5:128-134, 2003
    • (2003) Neoplasia , vol.5 , pp. 128-134
    • Woods Ignatoski, K.M.1    Grewal, N.K.2    Markwart, S.3


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