Differential regulation of glucocorticoid synthesis in murine intestinal epithelial versus adrenocortical cell lines

Endocrinology

Volumn 148, Issue 3, 2007, Pages 1445-1453

  Mueller, Matthias ^a   Atanasov, Atanas ^a   Cima, Igor ^a,c   Corazza, Nadia ^a   Schoonjans, Kristina ^b   Brunner, Thomas ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CYTOCHROME P450; GLUCOCORTICOID; LIVER RECEPTOR HOMOLOG 1; PHORBOL ESTER; STEROID 11BETA MONOOXYGENASE; STEROIDOGENIC FACTOR 1;

ADRENAL CORTEX CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; EPITHELIUM CELL; HORMONE SYNTHESIS; IMMUNOREGULATION; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEROIDOGENESIS; TRANSCRIPTION REGULATION;

ADRENAL CORTEX; ANIMALS; CELL LINE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYCLIC AMP; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HOMEODOMAIN PROTEINS; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RESPONSE ELEMENTS; STEROID 11-BETA-HYDROXYLASE; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 33847042331     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0591     Document Type: Article

References (39)

1. Sapolsky RM, Romero LM, Munck AU 2000 How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev 21:55-89
2. Parker KL, Rice DA, Lala DS, Ikeda Y, Luo X, Wong M, Bakke M, Zhao L, Frigeri C, Hanley NA, Stallings N, Schimmer BP 2002 Steroidogenic factor 1: an essential mediator of endocrine development. Recent Prog Horm Res 57:19-36
3. Chrousos GP 1995 The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 332:1351-1362
4. Ashwell JD, Lu FW, Vacchio MS 2000 Glucocorticoids in T cell development and function. Annu Rev Immunol 18:309-345
5. Vacchio MS, Papadopoulos V, Ashwell JD 1994 Steroid production in the thymus: implications for thymocyte selection. J Exp Med 179:1835-1846
6. Ito N, Ito T, Kromminga A, Bettermann A, Takigawa M, Kees F, Straub RH, Paus R 2005 Human hair follicles display a functional equivalent of the hypothalamic-pituitary-adrenal axis and synthesize cortisol. FASEB J 19:1332-1334
7. Thiboutot D, Jabara S, McAllister JM, Sivarajah A, Gilliland K, Cong Z, Clawson G 2003 Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1). J Invest Dermatol 120:905-914
8. Takeda Y, Miyamori I, Yoneda T, Iki K, Hatakeyama H, Blair IA, Hsieh FY, Takeda R 1994 Synthesis of corticosterone in the vascular wall. Endocrinology 135:2283-2286
9. Gomez-Sanchez CE, Zhou MY, Cozza EN, Morita H, Eddleman FC, Gomez-Sanchez EP 1996 Corticosteroid synthesis in the central nervous system. Endocr Res 22:463-470
10. Davies E, MacKenzie SM 2003 Extra-adrenal production of corticosteroids. Clin Exp Pharmacol Physiol 30:437-445
11. Cima I, Corazza N, Dick B, Fuhrer A, Herren S, Jakob S, Ayuni E, Mueller C, Brunner T 2004 Intestinal epithelial cells synthesize glucocorticoids and regulate T cell activation. J Exp Med 200:1635-1646
12. Hanley NA, Rainey WE, Wilson DI, Ball SG, Parker KL 2001 Expression profiles of SF-1, DAX1, and CYP17 in the human fetal adrenal gland: potential interactions in gene regulation. Mol Endocrinol 15:57-68
13. Ikeda Y, Swain A, Weber TJ, Hentges KE, Zanaria E, Lalli E, Tamai KT, Sassone-Corsi P, Lovell-Badge R, Camerino G, Parker KL 1996 Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development. Mol Endocrinol 10:1261-1272
14. Fayard E, Auwerx J, Schoonjans K 2004 LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis. Trends Cell Biol 14:250-260
15. 1 cyclin-mediated cell proliferation. Mol Cell 15:499-509
16. Schoonjans K, Dubuquoy L, Mebis J, Fayard E, Wendling O, Haby C, Geboes K, Auwerx J 2005 Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation. Proc Natl Acad Sci USA 102:2058-2062
17. Mueller M, Cima I, Noti M, Fuhrer A, Jakob S, Dubuquoy L, Schoonjans K, Brunner T 2006 The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine. J Exp Med 203:2057-2062
18. Moore CC, Brentano ST, Miller WL 1990 Human P450scc gene transcription is induced by cyclic AMP and repressed by 12-O- tetradecanoylphorbol-13-acetate and A23187 through independent cis elements. Mol Cell Biol 10:6013-6023
19. Bens M, Bogdanova A, Cluzeaud F, Miquerol L, Kerneis S, Kraehenbuhl JP, Kahn A, Pringault E, Vandewalle A 1996 Transimmortalized mouse intestinal cells (m-ICc12) that maintain a crypt phenotype. Am J Physiol 270:C1666-C1674
20. Lee HK, Lee YK, Park SH, Kim YS, Lee JW, Kwon HB, Soh J, Moore DD, Choi HS 1998 Structure and expression of the orphan nuclear receptor SHP gene. J Biol Chem 273:14398-14402
21. Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, Mangelsdorf DJ 2000 Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell 6:507-515
22. Ikeda Y, Lala DS, Luo X, Kim E, Moisan MP, Parker KL 1993 Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. Mol Endocrinol 7:852-860
23. Tillman JB, Crone DE, Kim HS, Sprung CN, Spindler SR 1993 Promoter independent down-regulation of the firefly luciferase gene by T3 and T3 receptor in CV1 cells. Mol Cell Endocrinol 95:101-109
24. Chau YM, Crawford PA, Woodson KG, Polish JA, Olson LM, Sadovsky Y 1997 Role of steroidogenic-factor 1 in basal and 3′,5′-cyclic adenosine monophosphate-mediated regulation of cytochrome P450 side-chain cleavage enzyme in the mouse. Biol Reprod 57:765-771
25. Kasibhatla S, Brunner T, Genestier L, Echeverri F, Mahboubi A, Green DR 1998 DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1. Mol Cell 1:543-551
26. Wang XL, Bassett M, Zhang Y, Yin S, Clyne C, White PC, Rainey WE 2000 Transcriptional regulation of human 11β-hydroxylase (hCYP11B1). Endocrinology 141:3587-3594
27. Watanabe N, Inoue H, Fujii-Kuriyama Y 1994 Regulatory mechanisms of cAMP-dependent and cell-specific expression of human steroidogenic cytochrome P450scc (CYP11A1) gene. Eur J Biochem 222:825-834
28. Denner K, Rainey WE, Pezzi V, Bird IM, Bernhardt R, Mathis JM 1996 Differential regulation of 11β-hydroxylase and aldosterone synthase in human adrenocortical H295R cells. Mol Cell Endocrinol 121:87-91
29. Black SM, Szklarz GD, Harikrishna JA, Lin D, Wolf CR, Miller WL 1993 Regulation of proteins in the cholesterol side-chain cleavage system in JEG-3 and Y-1 cells. Endocrinology 132:539-545
30. Krylova IN, Sablin EP, Moore J, Xu RX, Waitt GM, Mackay JA, Juzumiene D, Bynum JM, Madauss K, Montana V, Lebedeva L, Suzawa M, Williams JD, Williams SP, Guy RK, Thornton JW, Fletterick RJ, Willson TM, Ingraham HA 2005 Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell 120:343-355
31. Li Y, Choi M, Cavey G, Daugherty J, Suino K, Kovach A, Bingham NC, Kliewer SA, Xu HE 2005 Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1. Mol Cell 17:491-502
32. Wang W, Zhang C, Marimuthu A, Krupka HI, Tabrizizad M, Shelloe R, Mehra U, Eng K, Nguyen H, Settachatgul C, Powell B, Milburn MV, West BL 2005 The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1. Proc Natl Acad Sci USA 102:7505-7510
33. Ortlund EA, Lee Y, Solomon IH, Hager JM, Safi R, Choi Y, Guan Z, Tripathy A, Raetz CR, McDonnell DP, Moore DD, Redinbo MR 2005 Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. Nat Struct Mol Biol 12:357-363
34. Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, Galardi C, Wilson JG, Lewis MC, Roth ME, Maloney PR, Willson TM, Kliewer SA 2000 A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell 6:517-526
35. Lee YK, Moore DD 2002 Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner. J Biol Chem 277:2463-2467
36. Morohashi K, Hatano O, Nomura M, Takayama K, Hara M, Yoshii H, Takakusu A, Omura T 1995 Function and distribution of a steroidogenic cell-specific transcription factor, Ad4BP. J Steroid Biochem Mol Biol 53:81-88
37. Sasano H, Shizawa S, Suzuki T, Takayama K, Fukaya T, Morohashi K, Nagura H 1995 Ad4BP in the human adrenal cortex and its disorders. J Clin Endocrinol Metab 80:2378-2380
38. Rosenberg D, Groussin L, Jullian E, Perlemoine K, Bertagna X, Bertherat J 2002 Role of the PKA-regulated transcription factor CREB in development and tumorigenesis of endocrine tissues. Ann NY Acad Sci 968:65-74
39. Lee YK, Choi YH, Chua S, Park YJ, Moore DD 2006 Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation. J Biol Chem 281:7850-7855